• 综述探讨了脂肪细胞因子胰岛素活性中的作用研究了运动训练脂肪细胞因子的影响。

    This review explores the role of adipocytokines in insulin action and examines the effect of exercise training on adipocytokine content.

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  • 诺贝特烟酸非酒精脂肪肝患者肝内甘油三酯含量低密度脂蛋白动力学胰岛素活性影响

    Effect of Fenofibrate and Niacin on Intrahepatic Triglyceride Content, Very Low-Density Lipoprotein Kinetics, and Insulin Action in Obese Subjects with Nonalcoholic Fatty Liver Disease.

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  • 作用机制影响胰岛素信号通道各蛋白磷酸化表达及PKB活性因素有关。

    The mechanism may be involved in their affecting the phosphorylation and expression of insulin signaling proteins as well as PKB activity.

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  • 目的建立红细胞胰岛素受体酪氨酸蛋白激酶(IRTK)的活性测定

    Objective: to establish a method of detecting insulin receptor tyrosine kinase (IRTK) activity from erythrocytes.

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  • 通过体外活性筛选动物试验,首次发现唐古特瑞香95%乙醇提取物具有明显改善胰岛素抵抗作用。

    The in vitro and in vivo test indicated that the 95% ethanol extracts of Daphne tangutica Maxim showed obvious antidiabetic activity in amending insulin resistance.

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  • 目的探讨代谢综合征患者血浆纤溶活性及与胰岛素抵抗关系

    Objective: To investigate the relationship between plasma fibrinolytic activity and insulin resistance in patients with the metabolism syndrome.

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  • 寻找PTP1B特异性抑制剂,通过抑制PTP1B活性提高胰岛素信号通路的敏感性,对糖尿病肥胖症治疗有着重要的应用前景

    Inhibition of PTP1B's activity could improve the sensitivity of insulin signaling. The discovery of highly effective inhibitors of PTP1B has a promising application in diabetes and obesity therapy.

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  • 目的研究胰岛素剂量低血糖持续时间血清活性影响,确定低血糖损伤脏器

    Objective: to study the effects of insulin dosage and duration of hypoglycemia on serum enzyme activity in rabbits, and determine organ damage due to hypoglycemia.

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  • 阿斯匹林治疗可能通过普通病原性途径炎症胰岛素抵抗氧化应激、环氧化酶活性影响心血管疾病癌症

    Aspirin therapy may influence cardiovascular disease and cancer through its effect on common pathogenic pathways, such as inflammation, insulin resistance, oxidative stress, and Cox enzyme activity.

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  • 胰岛素诱导脂肪酸合成酶活性升高转录水平上调节的。

    The change of FAS activity during insulin induction is at the transcriptional level.

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  • 目的探讨胰岛素注射液启封无菌保存期,以及保存期内药物活性变化。

    Objective To study the asepsis period and immunological activity of insulin injection after removing seal.

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  • 结论冠心病患者纤溶系统活性异常胰岛素抵抗有关

    Conclusion it was suggested that the abnormal activities of fibrinolytic system is associated with insulin resistance in CHD.

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  • 啉锌显著抑制HO活性,阻止胰岛素心肌细胞保护作用。

    Znpp could inhibit HO activity and blockade the myocardial protective mechanism of insulin.

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  • GLUT4的亚细胞分布基因表达量以及功能活性,都将直接影响胰岛素作用下葡萄糖跨膜转运。

    The subcellular distribution, gene expression, and inherent activity of GLUT4 directly affect the glucose transmembrane transportation induced by insulin.

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  • 通过大量有代表性文献简要综述了胰岛素活性研究背景、研究进展作用机理等。

    Basing on the lots of representative literatures, this review summarized the researching background, development and acting mechanisms on the insulin - mimetic effects of vanadium.

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  • 通过大量有代表性文献简要综述了钒胰岛素活性研究背景研究进展作用机理等。

    Basing on the lots of representative literatures, this review summarized the researching background, development and acting mechanisms on the insulin-mimetic effects of vanadium.

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  • 两者胰岛素抵抗胰岛素缺陷提高了血小板活性

    Both insulin resistance and insulin deficiency increase platelet reactivity.

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  • 肝脏胰岛素抵抗表现为脂代谢异常,如甘油三酯释放增加肝脏脂肪变性,FOXO1转录活性增加有密切关系。

    Increased triglyceride release and hepatic steatosis are the common features of hepatic insulin resistance, which deeply associated with increased FOXO1 transcription.

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  • 高血糖症可以损害免疫系统胰岛素具有抗炎以及其他抗感染活性

    Hyperglycemia may impair the immune system, and insulin may have anti-inflammatory and other anti-infective activities.

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  • 目的设计合成胰岛素增敏活性的系列化合物

    Aim To design and synthesize compounds with insulin-sensitizing activity.

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  • 目的设计合成具备胰岛素增敏活性的系列化合物

    OBJECTIVE To design and synthesize compounds with insulin-sensitizing activity.

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  • 对丁酸转化前后红白血病细胞k- 562的表面胰岛素受体数量胰岛素受体酪氨酸蛋白激酶活性细胞内源性底物进行了研究

    In this paper, the quantity of insulin receptors and the receptor tyrosine kinase activity and its endogenous substrates were comparatively studied in K-562 cells before and after transformation.

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  • 目的探讨胰岛素受体酪氨酸激酶(TK)活性变化胰岛素抵抗(IR)发生中的作用。

    Objective to investigate the change of insulin receptor tyrosine kinase (TK) activity in the pathogenesis of insulin resistance (IR).

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  • 结论高血压患者RAS活性增加血浆胰岛素浓度增加密切相关,RAS活性增加可能胰岛素抵抗(IR)原因之一

    Conclusion the increased activity of RAS is correlated with the hyperinsulinemia and may be one of the causes of insulin resistance (IR).

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  • 目的探讨慢性乙型肝炎(慢性乙肝)患者外周血红细胞胰岛素活性(EIDEA)改变间接反映其肝脏胰岛素灭活功能的改变。

    Objective to investigate the change of the insulin degrading enzyme activity of erythrocytes (EIDEA) in patients with chronic hepatitis b, and to reveal the ability of the liver for degrading insulin.

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  • 脂联素脂肪细胞特异分泌一种生物活性分子,肥胖胰岛素抵抗等多种疾病相关

    Adiponectin is a specific secretory protein produced by adipocytes. Plasma adiponectin levels are intimately associated with obesity and insulin resistance.

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  • Src介导PP2A第307位酪氨酸磷酸化响应EGF或者胰岛素,最终导致PP2A的活性显著下降(4)。

    Phosphorylation of PP2A at Tyr307 by Src occurs in response to EGF or insulin and results in a substantial reduction of PP2A activity (4).

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  • 富铭酵母中的有部分有机形式GTF(葡萄糖耐量因子)存在。高活性GTF协助胰岛素维持正常耐量

    Chromium in the yeast partly exists in an organic species-glucose tolerance factor (GTF). The GTF with high activity can assist insulin to play a certain role in maintaining normal glucose tolerance.

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  • UCP2调节脂肪酸氧化,控制活性产生,抑制胰岛素分泌

    UCP2 limits production of reactive oxygen species (ROS) and inhibits insulin secretion and regulates fatty acid oxidation.

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  • UCP2调节脂肪酸氧化,控制活性产生,抑制胰岛素分泌

    UCP2 limits production of reactive oxygen species (ROS) and inhibits insulin secretion and regulates fatty acid oxidation.

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