本综述探讨了脂肪细胞因子在胰岛素活性中的作用和研究了运动训练对脂肪细胞因子的影响。
This review explores the role of adipocytokines in insulin action and examines the effect of exercise training on adipocytokine content.
非诺贝特和烟酸对非酒精脂肪肝患者肝内甘油三酯含量,极低密度脂蛋白动力学,胰岛素活性的影响。
Effect of Fenofibrate and Niacin on Intrahepatic Triglyceride Content, Very Low-Density Lipoprotein Kinetics, and Insulin Action in Obese Subjects with Nonalcoholic Fatty Liver Disease.
其作用机制与影响胰岛素信号通道各蛋白的磷酸化、表达及PKB活性等因素有关。
The mechanism may be involved in their affecting the phosphorylation and expression of insulin signaling proteins as well as PKB activity.
目的:建立红细胞胰岛素受体酪氨酸蛋白激酶(IRTK)的活性测定法。
Objective: to establish a method of detecting insulin receptor tyrosine kinase (IRTK) activity from erythrocytes.
通过体外活性筛选和动物试验,首次发现唐古特瑞香95%乙醇提取物具有明显改善胰岛素抵抗的作用。
The in vitro and in vivo test indicated that the 95% ethanol extracts of Daphne tangutica Maxim showed obvious antidiabetic activity in amending insulin resistance.
目的:探讨代谢综合征患者血浆纤溶活性及与胰岛素抵抗的关系。
Objective: To investigate the relationship between plasma fibrinolytic activity and insulin resistance in patients with the metabolism syndrome.
寻找PTP1B的特异性抑制剂,通过抑制PTP1B的活性来提高胰岛素信号通路的敏感性,对糖尿病和肥胖症治疗有着重要的应用前景。
Inhibition of PTP1B's activity could improve the sensitivity of insulin signaling. The discovery of highly effective inhibitors of PTP1B has a promising application in diabetes and obesity therapy.
目的:研究胰岛素剂量和低血糖持续时间对血清酶活性影响,确定低血糖损伤的脏器。
Objective: to study the effects of insulin dosage and duration of hypoglycemia on serum enzyme activity in rabbits, and determine organ damage due to hypoglycemia.
阿斯匹林治疗可能通过普通病原性途径,如炎症、胰岛素抵抗、氧化应激、环氧化酶活性来影响心血管疾病和癌症。
Aspirin therapy may influence cardiovascular disease and cancer through its effect on common pathogenic pathways, such as inflammation, insulin resistance, oxidative stress, and Cox enzyme activity.
胰岛素诱导后的脂肪酸合成酶活性升高是在转录水平上调节的。
The change of FAS activity during insulin induction is at the transcriptional level.
目的探讨胰岛素注射液启封后无菌保存期,以及保存期内药物活性变化。
Objective To study the asepsis period and immunological activity of insulin injection after removing seal.
结论冠心病患者的纤溶系统活性异常与胰岛素抵抗有关。
Conclusion it was suggested that the abnormal activities of fibrinolytic system is associated with insulin resistance in CHD.
原卟啉锌能显著抑制HO活性,阻止胰岛素对心肌细胞的保护作用。
Znpp could inhibit HO activity and blockade the myocardial protective mechanism of insulin.
GLUT4的亚细胞分布、基因表达量以及功能活性,都将直接降影响胰岛素作用下葡萄糖的跨膜转运。
The subcellular distribution, gene expression, and inherent activity of GLUT4 directly affect the glucose transmembrane transportation induced by insulin.
通过大量有代表性的文献,简要综述了钒的胰岛素样活性的研究背景、研究进展及作用机理等。
Basing on the lots of representative literatures, this review summarized the researching background, development and acting mechanisms on the insulin - mimetic effects of vanadium.
通过大量有代表性的文献,简要综述了钒的胰岛素样活性的研究背景、研究进展及作用机理等。
Basing on the lots of representative literatures, this review summarized the researching background, development and acting mechanisms on the insulin-mimetic effects of vanadium.
两者的胰岛素抵抗和胰岛素缺陷提高了血小板活性。
Both insulin resistance and insulin deficiency increase platelet reactivity.
肝脏胰岛素抵抗还表现为脂代谢异常,如甘油三酯释放增加和肝脏脂肪变性,这与FOXO1转录活性增加有密切关系。
Increased triglyceride release and hepatic steatosis are the common features of hepatic insulin resistance, which deeply associated with increased FOXO1 transcription.
高血糖症可以损害免疫系统,胰岛素具有抗炎以及其他抗感染活性。
Hyperglycemia may impair the immune system, and insulin may have anti-inflammatory and other anti-infective activities.
目的设计合成具胰岛素增敏活性的系列化合物。
Aim To design and synthesize compounds with insulin-sensitizing activity.
目的设计合成具备胰岛素增敏活性的系列化合物。
OBJECTIVE To design and synthesize compounds with insulin-sensitizing activity.
对丁酸钠转化前后的人红白血病细胞林k- 562的表面胰岛素受体数量、胰岛素受体酪氨酸蛋白激酶活性及细胞内源性底物进行了研究。
In this paper, the quantity of insulin receptors and the receptor tyrosine kinase activity and its endogenous substrates were comparatively studied in K-562 cells before and after transformation.
目的探讨胰岛素受体酪氨酸激酶(TK)活性变化在胰岛素抵抗(IR)发生中的作用。
Objective to investigate the change of insulin receptor tyrosine kinase (TK) activity in the pathogenesis of insulin resistance (IR).
结论高血压患者RAS活性增加与血浆胰岛素浓度增加密切相关,RAS活性增加可能是胰岛素抵抗(IR)的原因之一。
Conclusion the increased activity of RAS is correlated with the hyperinsulinemia and may be one of the causes of insulin resistance (IR).
目的探讨慢性乙型肝炎(慢性乙肝)患者外周血红细胞胰岛素酶活性(EIDEA)的改变,以间接反映其肝脏胰岛素灭活功能的改变。
Objective to investigate the change of the insulin degrading enzyme activity of erythrocytes (EIDEA) in patients with chronic hepatitis b, and to reveal the ability of the liver for degrading insulin.
脂联素是由脂肪细胞特异分泌的一种生物活性分子,与肥胖、胰岛素抵抗等多种疾病相关。
Adiponectin is a specific secretory protein produced by adipocytes. Plasma adiponectin levels are intimately associated with obesity and insulin resistance.
Src介导的PP2A第307位酪氨酸磷酸化响应EGF或者胰岛素,最终导致PP2A的活性显著下降(4)。
Phosphorylation of PP2A at Tyr307 by Src occurs in response to EGF or insulin and results in a substantial reduction of PP2A activity (4).
富铭酵母中的铬有部分以有机形式GTF(葡萄糖耐量因子)存在。高活性的GTF能协助胰岛素维持正常糖耐量。
Chromium in the yeast partly exists in an organic species-glucose tolerance factor (GTF). The GTF with high activity can assist insulin to play a certain role in maintaining normal glucose tolerance.
UCP2可调节脂肪酸氧化,控制活性氧簇的产生,抑制胰岛素分泌。
UCP2 limits production of reactive oxygen species (ROS) and inhibits insulin secretion and regulates fatty acid oxidation.
UCP2可调节脂肪酸氧化,控制活性氧簇的产生,抑制胰岛素分泌。
UCP2 limits production of reactive oxygen species (ROS) and inhibits insulin secretion and regulates fatty acid oxidation.
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