目的观察体外培养的胰岛干细胞是否可以被诱导分化为类胰岛样组织。
To observe whether the islet stem cells cultured in vitro can be induced to differentiate into pancreatic islet-like tissues.
资料选择：选择胰腺干细胞或胰岛干细胞移植治疗糖尿病的文章，排除重复研究。
Study SELECTION: The articles of pancreatic stem cell or islet stem cell transplantation for diabetes were selected, while those with repetitive study were excluded.
问题关键在于找到正确的诱导干细胞分化成心脏细胞，神经细胞，制造胰岛素的细胞或者其他细胞的生长因子的正确方法。
The key lay in finding just the right recipe of growth factors and nutrients to induce a stem cell to become a heart cell, a neuron, an insulin-making cell or something else.
然而在这项新的研究中，研究人员能够从男性的睾丸组织提取细胞，分离干细胞，使之成为能够分泌胰岛素的胰岛细胞。
In the new study, however, researchers were able to take cells from men's testicular tissue, isolate stem cells, and turn them into insulin-secreting islet cells.
研究者得出结论：这些发现表明人胚胎干细胞事实上可以在糖尿病的治疗上提供再生的胰岛素分泌细胞。
These findings suggest that human embryonic stem cells could, in fact, represent a renewable supply of insulin-producing cells for treating diabetes, the researchers conclude.
为此，调控干细胞分化为成熟的有功能的胰岛细胞成为近年来的研究热点。
So the study of regulating differentiation of stem cells toward mature, functional islets cells becomes the hotspot recently.
在实验中，科学家们已经成功地诱导胚胎干细胞分化为心肌细胞和分泌胰岛素的胰腺细胞。
In the laboratory, scientists have been able to induce embryonic stem cells to develop into heart muscle cells or insulin-producing cells of the pancreas.
巴西的一项研究显示，对1型糖尿病患者进行干细胞移植，可能会使胰腺重新开始分泌胰岛素。
Brazilian study has shown that stem cell transplants in patients with diabetes type 1 May kick start the pancreas into producing insulin again.
目的：探讨骨髓间充质干细胞(MSC)体外诱导转化为胰岛样细胞及其对坏死胰腺组织修复的可能性。
Objective To study the induction of islet-like cell from bone marrow mesenchymal stem cells (MSCs) in vitro and its repair effects on injury pancreas tissues.
之间有什么胰岛移植和干细胞研究的区别？
What is the difference between islet transplant and stem cell research?
目的：本文就近年来干细胞诱导分化为胰岛素分泌细胞的研究进展做一综述。
OBJECTIVE: This article is a review about the research progress of the differentiation from stem cells into islet-producing cells.
纳入标准：干细胞向胰岛素分泌细胞诱导分化的研究进展。
Inclusive criterion: Articles about research progress of the differentiation from stem cells into islet-producing cells were selected.
探讨小鼠骨髓干细胞有无被诱导分化为胰岛素分泌细胞的可能性。
ObjectiveTo study whether the mouse bone marrow-derived stem cells have the possibility to be induced into insulin-secreting cells.
单细胞反转录酶聚合链式反应检测胰岛素促进因子基因实验中，选择12个单个胰腺干细胞进行检测，另取12个单个未分化的干细胞作为对照。
In the detection of IPF1 gene with single cell RT-PCR, 12 single pancreatic stem cells were detected, and another 12 undifferentiated single pancreatic stem cells were taken as controls.
结论体外诱导骨髓基质干细胞定向分化为胰岛样细胞存在可行性。
Conclusion Functional islet-like cells can be differentiated from marrow mesenchymal stem cells, which may be a new procedure for clinical diabetes stem -cell therapy.
但是15个新诊断的年轻人中有14人在采用干细胞移植后几年内不需要注射胰岛素。
But 14 out of 15 young people newly diagnosed with the condition no longer needed injections - sometimes for years - following the stem cell treatment.
目的：目前在胰腺干细胞体外转分化为胰岛样细胞的转化效率，转分化胰岛样细胞的成熟度，能否代替天然胰岛的功能等问题上存在争议。
AIM: Transformation efficacy, maturity and function of replacing normal islets of in vitro differentiated pancreatic stem cells into islet-like cells are in debate.
目的：探讨骨髓间充质干细胞在胰岛移植中对胰岛移植物的潜在保护作用。
Objective: To explore the protection of bone marrow-derived mesenchymal stem cells in the islet transplantation in the potential of islet graft.
目的：探讨人骨髓源干细胞向具有功能的胰岛素分泌细胞分化的可能性。
AIM: To explore the possibility of differentiating functional insulin-producing cells from human BM-derived stem cells.
【目的】探讨小鼠骨髓干细胞有无被诱导分化为胰岛素分泌细胞的可能性。
ObjectiveTo study whether the mouse bone marrow-derived stem cells have the possibility to be induced into insulin-secreting cells.
经过干细胞移植，除一人以外，所有患者B细胞功能增强，使大多数患者可以持续脱离胰岛素。
With AHST, beta cell function was increased in all but 1 patient and induced prolonged insulin independence in the majority of the patients"."
经过干细胞移植，除一人以外，所有患者B细胞功能增强，使大多数患者可以持续脱离胰岛素。
With AHST, beta cell function was increased in all but 1 patient and induced prolonged insulin independence in the majority of the patients"."
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