• 一新的解释以往关于BCA1作用机制各不相干理论整合到一起其他肿瘤抑制因子作用机制的了解可能带来帮助。

    This explanation brings together many disparate theories about how the gene functions and could also shed light on how other tumour suppressors work.

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  • PTEN肿瘤抑制因子乳腺癌中虽表达并不是通过基因突变促进子甲基化而实现的,因此其失表达机制还不清楚。

    Expression of the PTEN tumor suppressor is frequently lost in breast cancer in the absence of mutation or promoter methylation through as yet undetermined mechanisms.

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  • 类似的相反作用其他肿瘤抑制因子中也发现H - REV107 - 1表达非小细胞肺癌病人存活期关联还是相当令人震惊

    Similar reverse functions have been identified for other tumor suppressors, but the correlation between H-REV107-1 expression and NSCLC patient survival is quite striking.

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  • 也就可以解释为什么试图通过血管生成抑制因子阻断血管生长信号而阻断肿瘤血液供应药物通常失去作用。

    She says that this could explain why cancer drugs aimed at choking off a tumor's blood supply by blocking growth signals, known as angiogenesis inhibitors, usually stop working within about 6 months.

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  • 结论HIFU治疗可以减少肿瘤局部免疫抑制因子表达,推测有利于肿瘤宿主免疫平衡恢复

    Conclusions: HIFU treatment could reduce the expression of local immunosuppressive factors. It would be helpful to the recovery of the balance between host antitumor immunity and tumor escape.

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  • TGF配体虽然早期肿瘤作为肿瘤抑制基因发挥作用,其在进展肿瘤变成有效的促转移因子

    TGF ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers.

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  • 单抗通过抑制被称为血管内皮生长因子蛋白,来抑制肿瘤组织新生血管的生长。

    Bevacizumab blocks a protein called vascular endothelial growth factor, thus inhibiting the production of new blood vessels around tumors.

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  • 结论实验表明水蛭素活性因子S180肿瘤CAM新生血管具有较强抑制作用

    ConclusionThe experiments show that hirudin active factors have strong inhibition effect on S180 Tumor and CAM angiogenesis.

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  • 研究表明干扰素可以通过抑制肿瘤依赖性转录因子表达来达到抑制肿瘤的作用,这种转录因子可以调控肿瘤细胞生长

    The present study indicates that interferon can suppress cancer growth by inhibiting expression of a cancer-dependent transcription factor that controls genes that regulate cancer cell growth.

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  • 凋亡抑制因子肿瘤进展中的作用日益受到人们的关注。

    We are attracted by the function of inhibitor of apoptosis in carcinoma progression.

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  • 目的观察妇科恶性肿瘤患者血清、腹腔液噬细胞移动抑制因子(MIF)表达及其恶性肿瘤相关性。

    Objective to investigate the expressions of macrophage migration inhibitory factor (MIF) in gynecologic malignancy tumor patients and the correlation between VEGF and CA125.

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  • 目的探讨直肠癌组织中脑特异性血管生长抑制因子1 (BAI1)基因表达情况及BAI1对肿瘤血管生成肿瘤生长作用

    Objective to explore the expression of brain-specific angiogenesis inhibitor 1 (BAI1) gene in rectal cancer tissues and its effect on growth and angiogenesis of the tumor.

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  • 摘要肿瘤化学预防,即应用天然合成或者生物化学因子逆转抑制阻止肿瘤进展浸润性肿瘤

    Cancer chemoprevention is defined as the use of natural, synthetic, or biologic chemical agents to reverse, suppress, or prevent carcinogenic progression to invasive cancer.

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  • 血管形成实体肿瘤增殖转移关键步骤一过程依赖内源性刺激因子抑制因子之间平衡

    Angiogenesis is the key step in tumors proliferation and metastasis, which depends on the net balance between endogenous stimulators and inhibitors.

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  • 本文综述包括肿瘤坏死因子抑制白细胞介素1抑制干细胞移植基因治疗生物治疗类风湿性关节炎治疗中的作用

    This article reviews the effect of biotherapy in ra including tumor necrosis factor inhibitor, IL-1inhibitor, stem cell transplantation genetic therapy and so on.

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  • 肿瘤坏死因子受体抑制可溶性重组

    Tumor Necrosis Factor Receptor Inhibitor, Human Soluble, recombinant.

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  • 目的研究T细胞细胞游走抑制因子(MIF)基因修饰瘤苗诱导肿瘤免疫反应中的作用

    Objective: To investigate the role of t cell in the antitumor immune responses induced by MIF gene modified tumor vaccine.

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  • 促进因子作用强于抑制因子时,便引起肿瘤血管的生长。

    When the effects of enhancing factors are stronger than those of inhibiting factors, it will cause unrestricted tumor neovascularization.

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  • 肿瘤血管生成肿瘤生长转移关键步骤血管生成因子抑制因子作用失衡结果

    Tumor angiogenesis, resulting from the imbalance of angiogenic cytokines and angiogenesis inhibitors, is crucial for tumor growth and metastasis.

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  • 转录因子NF-IL6特异地肿瘤组织过量表达,许多报道表明抑制功能肿瘤治疗有利。

    NF-IL6 is specifically overexpressed in tumor tissues. Many reports have shown that abrogation of transcriptional activation activity is useful for tumor therapy.

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  • 目的观察血管内皮生长因子(VEGF)抗体大鼠c6胶质瘤细胞凋亡影响肿瘤生长抑制作用。

    Objective to observe the affect of vascular endothelial growth factor (VEGF) antibody on the cell apoptosis and growth of rat C6 glioma.

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  • 内皮抑素血管生成抑制因子,它特异性作用于新生微血管内皮细胞水平肿瘤血管生成有着明显的相关性。

    Endostatin is a kind of angiogenesis inhibitor, specific effecting in the new microvascular endothelial cells. The level of endostatin and the angiogenesis of tumor have a close correlation.

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  • 目的:探讨间接酶联免疫吸附试验(ELISA检测核糖核酸酶抑制因子RI恶性肿瘤患者血清中的表达

    Objective: To detect the expression of ribonuclease inhibitor (RI) in the serum of patients with malignant tumors by indirect ELISA.

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  • 血管生成促进因子血管生成抑制因子平衡控制着肿瘤新生血管形成。

    Formation of tumor new vessels is controlled by balances between angiogenic stimulators and inhibitors.

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  • 目的克隆表达一种新的血管形成抑制因子,并研究其抗肿瘤活性。

    Objective A new angiogenesis inhibitor HIAF 1 (human inhibitor angiogenesis factor 1) was cloned, expressed in E.

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  • 内皮抑素一种新的强烈抑制血管形成抑制因子,内皮抑素水平肿瘤具有明显相关性,水平可以作为肿瘤临床预后指标

    Endostatin is a new inhibitor factor which can intensively inhibit angiogenesis. The level of endostatin is significantly related to tumor, which can be a prognostic indicator of tumor.

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  • 肿瘤抑制蛋白p21Waf1/Cip1可以作为细胞周期抑制因子

    The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression.

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  • 肿瘤坏死因子抑制已经证明成功减少AS疾病活动数量有限临床试验

    Tumor necrosis factor inhibitors have demonstrated success in reducing as disease activity in a limited number of clinical trials.

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  • 肿瘤坏死因子抑制已经证明成功减少AS疾病活动数量有限临床试验

    Tumor necrosis factor inhibitors have demonstrated success in reducing as disease activity in a limited number of clinical trials.

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