厌氧菌能在肿瘤乏氧及坏死区选择性定植，引起溶瘤效应；
Anaerobic bacteria can selectively colonize and cause oncolysis in hypoxic and necrotic areas of solid tumors.
生物还原剂是一种具有肿瘤乏氧靶向性的前药，它会在还原性环境中被还原产生具有细胞毒性的代谢物。
Bio-reductive drugs are pro-drugs that can selectively target the hypoxia cells in tumors. In reductive environment, they are reductively metabolized to generate toxic species.
结论肿瘤乏氧与VEGF表达关系密切，乏氧可诱导VEGF表达的增高，而VEGF表达能促进肿瘤血管生成。
Conclusion tumor hypoxia had a close relationship with the expression of VEGF, and VEGF could promote tumor angiogenesis.
PET可以早期准确地反映肿瘤相关生物特征，如血管生成、凋亡、乏氧和增殖等。
The relative biological features as angiogenesis, apoptosis, hypoxic and proliferation can be reflected by PET early and correctly.
乏氧肿瘤细胞对放射治疗、化学治疗的耐受性增强。
Hypoxic tumor cells exhibit increased resistance to radiotherapy and chemotherapy.
乏氧肿瘤细胞的存在是患者恶性肿瘤治疗失败、复发和转移的重要原因之一。
The existence of hypoxic cells is one of the most important reasons for treatment failure, relapse and metastasis.
急性和慢性乏氧可能在肿瘤中导致不同的生物学效应，并且其可能对于乏氧肿瘤治疗的新疗法设计直接产生影响。
Acute and chronic hypoxia might lead to different biology within the tumour and this might have a direct effect on the design of new therapies for the treatment of hypoxic tumours.
我们知道，乏氧的肿瘤组织区域对治疗往往耐受，且与临床预后不良有关。
Areas of hypoxic tumour tissue are known to be resistant to treatment and are associated with a poor clinical prognosis.
我们知道，乏氧的肿瘤组织区域对治疗往往耐受，且与临床预后不良有关。
Areas of hypoxic tumour tissue are known to be resistant to treatment and are associated with a poor clinical prognosis.
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