目的建立气管注入细菌致兔急性肺损伤(ALI)模型，为研究细菌致ali的致病机制及其治疗提供理论依据。
Objective: to establish the rabbit model of acute lung injury (ALI) by intratracheal instillation of Escherichia coli, and to study the pathogenesis of bacteria-induced ALI.
粪肠球菌是顽固性和继发性根管感染中最易分离到的细菌，其主要致病机制之一是形成生物膜。
Enterococcus faecalis (E. faecalis) is most frequent isolated from teeth with failed endodontic treatment. Biofilm-formation is one of the most important pathogenic mechanisms in post-treatment teeth.
与病毒相比，真菌、细菌弱致病菌及其诱导抗病机制的研究相对滞后。
The study of resistance mechanism induced by fungi and bacteria lagged behind that of virus.
对嗜肺军团菌分泌系统及效应蛋白的研究不仅能够帮助阐明病原细菌的致病机理，还有助于推动对宿主免疫机制的更深层次的研究。
Researching on T4BSS and effectors could not only help investigate the pathogenesis of intracellular bacterial pathogens, but also promote the comprehension about innate immune responses of hosts.
对嗜肺军团菌分泌系统及效应蛋白的研究不仅能够帮助阐明病原细菌的致病机理，还有助于推动对宿主免疫机制的更深层次的研究。
Researching on T4BSS and effectors could not only help investigate the pathogenesis of intracellular bacterial pathogens, but also promote the comprehension about innate immune responses of hosts.
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