HPV感染后可以导致被感染细胞的过度增殖和恶性转化。
The cells infected by HPV can have over proliferation and malignant transformation.
这反过来就导致了肾脏细胞的过度增殖,形成数以千计的囊肿,最终破坏肾脏。
This, in turn, causes excess growth and proliferation of kidney cells, which results in the formation of thousands of cysts that eventually destroy the kidney.
对该基因表达的抑制可引起成肌细胞的过度增殖和肌纤维的肥大,从而引起骨骼肌增生。
The inhibition of Myostatin expression can accelerate the myoblast proliferation and myofibril hypertrophy, which results in the skeletal muscle hyperplasia.
化学活性高的自由基可使不饱和脂肪酸过度氧化,使细胞功能突变或衰退,引起组织增殖和坏死而产生置人于死地的疾病。
Chemistry high activity of free radicals can make the unsaturated fatty acid oxidation, making the cell function excessively, or recession mutations and proliferation and necrosis centralis disease.
目的:即往人们认为肿瘤发生的原因是细胞增殖分化异常而导致的细胞增殖过度。
Objective: Formerly people considered the reason of tumor happen is cell proliferate and differentiate abnormality to result in cell proliferate exorbitant.
背景与目的:肺纤维化是一种病因复杂的疾病,以成纤维细胞过度增殖、胶原蛋白沉积为特征。
Background and Objective: The pathogenesis of pulmonary fibrosis is complicated, it is characterized with myofibroblast hyperplasia and deposition of collagen protein.
结论推测凋亡增多伴随细胞过度增殖是机体维持细胞动力学稳定的一种保护性机制。
Conclusion The increase of apoptosis and hyperplasia of keratinocytes may be one of protecting mechanisms to maintain stability of cell dynamics of body.
血管平滑肌细胞过度增殖及游移所致的血管内膜增生是术后血管再通的主要障碍。
The major complication of vascular recanalization is intimal hyperplasia which in due mainly to over-proliferation and migration of smooth muscle cells(SMC).
结论:PM X能诱导NTD的发生,其机制可能是因为PMX阻断了叶酸代谢通路并导致神经上皮细胞的增殖抑制和过度凋亡。
Conclusion: NTD embryos were induced by PMX, the mechanism of which might be PMX inhibited folate metabolism pathway and led to decreased cellular proliferation and excessive cellular apoptosis.
提示银屑病皮损表皮角朊细胞的病理改变是始发于角朊细胞凋亡异常增多,继而出现角朊细胞过度增殖。
It is suggested that abnormal increased apoptosis is the primary event of epidermal pathology in psoriasis, then hyperproliferation of keratinocyte follows.
血管平滑肌细胞过度增殖及游移所致的血管内膜增生是血管成形术后再狭窄的重要原因之一。
The major complication of vascular recanalization is intimal hyperplasia which in duc mainly to over-proliferation and migration of smooth muscle cells (SMC).
鹿茸多肽可促进骨性关节炎软骨细胞增殖,并可抑制骨性关节炎软骨细胞中金属蛋白酶的过度表达,可能对治疗骨性关节炎有较好的作用。
Pilose antler peptide can promote the proliferation of OA chondrocytes of rabbits , inhibit the overexpression of MMPs of OA chondrocytes. It can possibly play a effective role in the treatment of OA.
本发明还公开了该类化合 物或其盐在治疗肿瘤中的应用,所述的用途可通过抑制有丝分裂,从而发挥其抑制细胞过度增殖的功效;
The invention also discloses the application of the compounds and the salt in treating tumor; the usage can play the role of inhibiting over proliferation of cell through inhibiting cell mitosis;
本发明还公开了该类化合 物或其盐在治疗肿瘤中的应用,所述的用途可通过抑制有丝分裂,从而发挥其抑制细胞过度增殖的功效;
The invention also discloses the application of the compounds and the salt in treating tumor; the usage can play the role of inhibiting over proliferation of cell through inhibiting cell mitosis;
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