该基因编码的一种蛋白质,也被称为趋化因子受体CXCR4,同样有助于艾滋病毒感染免疫细胞。
The gene codes for a protein, also called CXCR4, that also helps HIV infect immune cells.
嗜酸性粒细胞通过趋化作用对过敏反应中的组胺、免疫复合物和嗜酸性粒细胞趋化因子(肥大细胞脱粒肽)做出反应。
They respond chemotactically to histamine, immune complexes, and eosinophil chemotactic factor of anaphylaxis, a substance released by degranulating mast cells.
两种最为有效的中性粒细胞趋化因子是细菌产物和补体系统片断。
The two most significant chemotactic agents for neutrophils are bacterial products and components of the complement system.
单核细胞趋化蛋白- 1是引起慢性炎症的主要趋化因子并且在心力衰竭的发病学中起着重要作用。
Monocyte chemoattractant protein-1 is the main chemotactic factor for the pathogenesis of chronic inflammation and plays an important role in the pathogenesis of heart failure.
最近越南的临床研究报道,H5N1感染病人比普通流感病毒感染产生更高水平的细胞因子和趋化因子——参与炎症的分子信使。
A recent clinical study in Vietnam showed that H5N1 patients had higher levels of cytokines and chemokines-molecular messengers involved in inflammation-than patients with seasonal flu had.
部分趋化因子通过趋化和调节免疫效应细胞的功能来发挥抗肿瘤免疫作用。
Some chemokine can be used in anti-tumor immunotherapy by its chemotactic function on tumor cells.
目的探讨慢性移植肾肾病大鼠模型肾组织中单核细胞趋化因子1(MCP 1)和RANTES的表达及意义。
Objective To investigate the expression of monocyte chemoattractant protein 1 (MCP-1) and RANTES and their significance in the pathogenesis of chronic allograft nephropathy.
目的观察重组人单核细胞趋化因子- 1 (MCP- 1)对骨肉瘤细胞种植的预防作用,并探索其作用剂量。
Objective to observe the preventing function of recombinant human MCP-1 (Monocyte Chemoattractant Protein-1) on the plantation of human osteosarcoma cells and to study the dose.
本文主要综述炎症细胞、细胞因子、趋化因子、黏附分子等炎症因子对脑组织损伤的影响。
This paper would review the role of inflammatory cells and mediators such as cytokines, chemotactic factors, adhesion molecules on cerebral tissue injury.
目的研究次级淋巴组织趋化因子(SLC)基因转染对小鼠恶性黑色素瘤细胞生物学特性的影响。
Objective To investigate the effects of secondary lymphoid organ chemokine (SLC) gene transfer on the biological characteristics of murine melanoma cells.
结论西替利嗪可能通过抑制角质形成细胞趋化因子的表达而发挥抗皮肤过敏炎症作用。
Conclusion Cetirizine may exert the anti-allergic inflammatory effects of skin by inhibiting the expression of chemokines in human keratinocytes.
目的探讨中性粒细胞趋化因子(CINC)在重症急性胰腺炎(SAP)发病机制中的作用。
Objective to investigate the role of cytokine-induced neutrophil chemoattractant (CINC) in the pathogenesis of severe acute pancreatitis (SAP).
应用四色荧光活化流式细胞术(FACS)检测CD 34 +细胞其粘附分子及趋化因子受体CXCR -4的表达谱。
Four color fluorescence activated cell sorting (FACS) analysis was applied to detect the expression profiles of adhesion molecules and chemokine receptor CXCR 4 on CD34 bright cells.
目的研究细胞趋化因子受体5(CCR5)在乙型病毒性肝炎(HB)免疫发病机制中的作用。
Objective To investigate the role of CC chemokine receptor 5(CCR5) in the immunological pathogenesis of hepatitis B(HB). ?
目的探讨人次级淋巴组织趋化因子浓度梯度对肿瘤细胞免疫逃逸的影响。
Objective To explore the effects of SLC concentration gradient on suppression of tumor immune escape.
结论:趋化因子的上调与巨噬细胞的聚集、胰岛移植物的破坏有关。
Conclusion Upregulated chemokines were associated with macrophage recruitment and destruction of islet xenografts.
近年来的研究发现,器官特异性表达的趋化因子及癌细胞表达的受体介导的趋化运动在肿瘤的侵袭和转移过程中发挥着重要的作用。
Recent data indicated that chemotaxis, which involves the chemokines expressed at specific organs and their receptors expressed on tumor cells, plays a crucial role in tumor invasion and spreading.
目的分析小鼠胸腺树突状细胞株(MTDC)中化学趋化因子的类型。
Objective To analyze the types of chemokines expressed in murine medullary thymic dendritic cell line (MTDC).
在细菌感染的早期,这些细胞的数量增多,控制细菌的繁殖,并分泌产生细胞因子和趋化因子。
These cells can have several roles during the early stage of an infection including controlling bacterial replication and producing cytokines and chemokines that activate and recruit additional cells.
结果:研究表明许多肿瘤细胞表达趋化因子CXCL12和受体CXCR4,与肿瘤细胞的迁移与转移有密切关系。
Results: Researchs indicated that various tumor cells expressed chemotactic factor CXCL12 and its receptor CXCR4, which was closely related to migration and metastasis of tumor cells.
目的:探讨趋化因子受体CXCR4表达水平对人肺癌细胞转移潜能的影响。
Objective: to study the effect of the expression levels of Chemokine receptor CXCR4 on the metastatic potential of human lung cancer.
目的:探讨大鼠脊髓损伤后中性粒细胞趋化因子(CINC -1)表达的变化规律。
AIM: to study the changes of expression of cytokine induced neutrophil chemoattractant (CINC 1) in rats after spinal cord injury.
目的观察趋化因子sdf- 1促内皮祖细胞增殖、迁移和管型形成的作用。
Objective to explore the effect of chemokine SDF-1 on the proliferation, migration and in vitro of human endothelial progenitor cells (EPCs).
前言:目的:研究内毒素作用于新生大鼠后,肺组织趋化因子-基质细胞衍生因子(CX CL12)表达的变化及可能作用。
Objective: To investigate the expression of CXCL 12 and its potential functions in neonatal rat lung caused by lipopolysaccharide (LPS).
趋化因子受体CCR5是HIV?1 进入靶细胞的辅助受体,因而成为开发抗艾滋病药物的新靶点。
CCR5, one of the coreceptors of HIV?1, is a new target of anti-HIV therapy.
趋化因子及其受体是肿瘤细胞生物学行为的重要调节因素。
Chemokines and chemokine receptors are important regulatory factors in tumor behaviors.
有证据表明特殊趋化因子通路可能促进单核细胞在发炎的组织中聚集,但在动脉粥样硬化的动脉中缺乏显著证据。
Evidence that particular chemokine pathways may cooperate to promote monocyte accumulation into inflamed tissues, particularly atherosclerotic arteries, is still lacking.
有证据表明特殊趋化因子通路可能促进单核细胞在发炎的组织中聚集,但在动脉粥样硬化的动脉中缺乏显著证据。
Evidence that particular chemokine pathways may cooperate to promote monocyte accumulation into inflamed tissues, particularly atherosclerotic arteries, is still lacking.
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