首先,他引入了一种能够导致肌生成抑制素的受体受到抑制的基因,使肌肉细胞的细胞膜表面的分子收到停止生长的信息。
First, he has introduced a gene that turns out a stunted version of the myostatin receptor, the molecule that sits in the surface membrane of muscle cells and receives the message to stop growing.
这种染色体异常使控制细胞生长的关键肿瘤抑制基因失活。
Such chromosomal abnormalities inactivate tumor - suppressor genes that are critical for controlling cell growth.
探讨肿瘤抑制基因对肺腺癌细胞生长的抑制作用。
To investigate the suppression effect of tumor suppressor gene in lung adenocarcinoma cells.
已有研究显示,RNA干扰下调肝癌形成相关基因的表达能有效抑制肝癌细胞的生长。
It has been reported the growth of liver cancer can be effectively controlled by specific gene silencing by RNAi.
癌转移抑制基因是一类只抑制癌细胞的转移而不影响肿瘤的发生与生长的基因。
Tumor metastasis suppressor gene is a kind of genes that only suppresses metastasis without affecting tumorigenicity and tumor growth.
一般来说抗真菌转基因的目标是加固植物细胞壁和产生抗真菌蛋白以直接或间接抑制真菌生长。
Generally the transgenes for fungal resistance are targeted towards reinforcement of plant cell walls or inhibiting the growth of fungal pathogens by producing antifungal proteins.
结论:利用RNA干扰PPO基因,从反面证实PPO与增殖和磷酸化有关,并且从细胞水平到活体水平,均证实能够抑制卵巢癌细胞的生长。
Conclusion: it is identified that the PPO gene relates to proliferation and phosphorylation from reverse and the ovarian cancer cells can be suppressed by RNA interference from in vitro to in vivo.
第10号染色体同源丢失性磷酸酶-张力蛋白基因(PTEN)作为肿瘤抑制基因,可以负性调节肿瘤细胞的生长。
As a tumor-suppressor gene, phosphatase and tensin homology deleted on chromosome 10 (PTEN) regulates negatively the growth of tumor cells.
它在鼻咽癌细胞和组织中表达明显下调,过表达BRD7基因可抑制鼻咽癌细胞的生长和细胞周期的进程。
It is obviously down-regulated in nasopharyngeal carcinoma (NPC) cells and tissues. Over expression of BRD7 in NPC cells can inhibit cell proliferation and cell cycle progression.
UCSD研究者也对丢失肿瘤抑制基因的小鼠进行研究。肿瘤抑制基因可以阻止细胞生长。
The UCSD researchers also studied mice that were missing a tumor suppressor gene, which is a gene that ACTS to prevent cell growth.
而在胚胎试验中,他抑制了产生反转录酶的癌细胞的基因,同样发现肿瘤的生长变慢了。
As in the embryo experiments, he then silenced the cancer-cell genes that produced reverse transcriptase, and likewise found the tumours grew more slowly.
结果人LIF基因可在COS - 7细胞中进行有效表达,表达产物对HL - 60白血病细胞具有抑制生长和诱导凋亡的作用。
Results the LIF gene can express in COS-7 cells and the product exhibits following functions on HL-60 cells: inhibiting growth, inducing apoptosis.
获得敲除肌肉生长抑制素(MSTN)基因的猪胎儿成纤维细胞。
The objective of this study is to get MSTN knock-out porcine fetal fibroblast.
BDNF基因修饰的大鼠淋巴细胞的培养上清可降低H2O2和DA对PC 12细胞生长的抑制率并能抑制H2O2和DA诱导PC 12细胞凋亡。
ResultsThe supernatant of lymphocytes modified by BDNF gene decreased the growth inhibitory rate and apoptosis rate of PC12 cells induced by H2O2 and DA.
通过直接肌肉内注射进行基因转染,p X1具有诱导肝癌细胞凋亡、抑制肝癌生长的作用。
The transfection of plasmid pX1 by injection into muscle of mouse could produce the inhibitory effect on liver carcinoma growth by inducing cells…
目的:探讨更昔洛韦对转染TK基因的骨髓瘤细胞生长的抑制作用。
Objective: To illustrate the effect on myeloma cells with TK gene by GCV.
HBP1通过抑制促细胞增殖基因mif的表达抑制肿瘤细胞生长。
HBP1 inhibition of cancer cells growth is achieved at least partially by suppressing MIF expression.
转移抑制基因是一类只抑制癌细胞的转移但不影响肿瘤发生和生长的基因。
Tumor metastasis suppressor genes is a kind of genes that only suppresses tumor metastasis without affecting tumorigenesis and tumor growth.
结论:向胃癌细胞中导入外源性FHIT基因可以抑制肿瘤细胞增殖,诱导细胞凋亡并引起细胞生长周期阻滞。
Conclusions: Transfecting the exogenous FHIT gene into gastric cancer cells can suppress the proliferation of tumor cells, and can also induce apoptosis and cell cycle arrest.
结论pcna基因反义rna对胃癌细胞的生长具有明显的抑制作用。
Conclusion PCNA antisense RNA can significantly suppress the in vitro growth of gastric cancer cell line.
实验结果表明,联合应用自杀基因与细胞因子基因治疗可更有效诱导机体的抗肿瘤免疫反应,从而更显著地抑制荷瘤小鼠肿瘤的生长。
Our results demonstrated that combined transfer of suicide gene and IL-2 gene could inhibit the growth of established tumor in mice significantly and induce antitumor immunity of the host efficiently.
实验结果表明,联合应用自杀基因与细胞因子基因治疗可更有效诱导机体的抗肿瘤免疫反应,从而更显著地抑制荷瘤小鼠肿瘤的生长。
Our results demonstrated that combined transfer of suicide gene and IL-2 gene could inhibit the growth of established tumor in mice significantly and induce antitumor immunity of the host efficiently.
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