游离二氧化硅致肺组织纤维化机制十分复杂，涉及多种细胞及生物活性物质参与的炎症反应、免疫反应、异物反应、细胞毒作用等。
The mechanism of fibrosis caused by free silica particles involves a lot of cells and reactions including inflammatory reaction, immunological reaction, foreign body reaction and cell toxic action.
这种作用可能与其直接细胞毒作用和激活免疫反应有关。
This effect may be related to direct cytotoxicity and immune response.
目的研究负载肿瘤抗原的树突细胞能否诱导特异性细胞毒t淋巴细胞反应。
Objective to explore the specific cytotoxic t lymphocyte (CTL) response induced by DC pulsed with tumor lysates from multiple myeloma patients.
目的探讨干预慢性迟发性超敏反应(DTH)与CD 8 +T淋巴细胞的细胞毒等效应机制对同种小鼠心脏移植后慢性排斥反应的影响。
Objective to evaluate the effect of delayed type hypersensitivity (DTH) and CD8 t lymphocyte cytotoxicity intervention on the development of chronic rejection in mouse cardiac allografts.
方法应用重导向细胞毒实验，探讨了PTA1分子对混合淋巴细胞反应中活化的NK细胞杀伤作用的影响。
Methods Redirected cytotoxicity assay (RCA) was used to detect the effect of PTA1 on cytotoxicity of NK cells generated from mixed lymphocyte culture (MLC).
目的：研究多发性骨髓瘤(MM)患者肿瘤冻融物致敏的树突细胞(DC)能否诱导特异性细胞毒t淋巴细胞(CTL)反应。
Objective: to explore the specific cytotoxic t lymphocyte (CTL) response induced by DC pulsed with tumor lysates from multiple myeloma (MM) patients.
传统肿瘤化学治疗的主要目的是杀伤癌细胞，但此类细胞毒性药物难以避免选择性差和毒副反应大等缺点。
The main aim of traditional tumour chemical therapy is to kill and wound cancer cells, but this kind of cytotoxicity drugs are hard to avoid weak selectivity, big side effect etc. , shortcomings.
摘 要：目的： 探讨利用癌症患者自体成纤维细胞作为抗原提呈细胞，诱导抗肿瘤的细胞毒T淋巴细胞（CTL）反应的可能性。
Objective: To characterize and develop a potential of activating tumor-specific cytotoxic T lymphocyte(CTL) responses with autologous fibroblasts of cancer patients.
摘 要：目的： 探讨利用癌症患者自体成纤维细胞作为抗原提呈细胞，诱导抗肿瘤的细胞毒T淋巴细胞（CTL）反应的可能性。
Objective: To characterize and develop a potential of activating tumor-specific cytotoxic T lymphocyte(CTL) responses with autologous fibroblasts of cancer patients.
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