• 用端重复序列扩增法(TRAP)半定量方法测定细胞染毒前后端粒酶活性变化

    The changes of telomerase activity after treatment was detected and quantified by telomeric repeat amplification protocol (TRAP) semi_quantitative analysis.

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  • 目的探讨香烟烟雾溶液染毒人正常细胞细胞DNA损伤及其修复效应。

    Objective to study the DNA damage and repair of normal lung interstitial cells and human lung adenocarcinoma cells exposed to cigarette smoke.

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  • 染毒细胞DNA链断裂迁移长度显著增加且存在剂量效应关系

    The movements of DNA migration in the BALF and lung cells increased with a dose effect relationship.

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  • 结果染毒浓度增加染毒时间的延长,骨髓细胞DNA迁移率迁移度增加

    Results DNA damage of bone marrow cells increased with the increase of benzene concentration and time of treatment.

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  • 目的研究HSP70乐果染毒u 87细胞中的保护作用

    Objective To investigate the protective effect of HSP70 in U87 cell line treated with dimethoate.

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  • 目的探讨二硫化染毒小鼠心肌细胞凋亡影响

    Objective to study the effect of carbon disulfide infection of mice myocardial cell apoptosis.

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  • 结果:随染毒剂量增加染料木素L 5178y细胞毒性增大。

    Results: Cytotoxicity of genistein for L5178Y cells increased dose-dependently.

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  • 细胞整体水平显示铅染毒巨噬细胞吞噬功能明显降低

    The phagocytosis of macrophages of lead-treated significantly decreased both at cellular and whole animal levels.

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  • 结果各水样处理H4IIE细胞,H4IIE细胞增殖染毒时间剂量增加而呈下降趋势。

    Result After exposed to the extracts, the proliferation of H4IIE cell decreased according to the exposure time and dose.

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  • 结果染毒小鼠脾、肾组织细胞DNA出现损伤损伤程度染毒剂量具有一定相关性

    Results DNA of spleen, liver, lung and kidney cells was significantly damaged after exposure, and there were some correlation between exposure concentration and damage degree.

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  • MTT法测定氰戊酯对MLTC-1细胞活力影响,确定染毒剂量。

    The cell viability of MLTC-1 cells affected by fenvalerate was analyzed using the method of MTT. 3.

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  • 目的应用胸腺dna染毒丙烯腈(AN)小鼠细胞研究anDNA作用,研究AN作用分子机制

    Objective to study the cross-link effect on DNA and the toxic mechanism of acrylonitrile (an) using calf thymus DNA and spermatids of an exposed mice.

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  • 目的观察及砷氟联合染毒SGC 790 1细胞基因组dna损伤作用及特点

    Objective To study the features of DNA damage induced by arsenic, fluoride and their combination in cultured SGC 7901 cells.

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  • 方法:通过建立新生大鼠皮层神经元原代培养,用不同浓度醋酸染毒给予牛磺酸干预,观察神经细胞生长和存活情况。

    Methods:Put taurine and different concentrations of lead acetate in cultures of cortex neurons and observe the length of dendites and the growth activity of neurons.

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  • 采用染色体畸变试验,检测染毒小鼠骨髓淋巴细胞染色体畸变改变。

    Before and after the mice were contaminated with various dosage of Wanelin, the rate of chromosome aberration of marrow lymphocytes were tested by chromosome aberration assay.

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  • 目的利用三氯乙烯TCE染毒小鼠模型研究TB淋巴细胞细胞因子TCE诱发过敏反应中的作用。

    Objective To investigate the effects of T and B lymphocytes and cytokines on allergic reaction induced by trichloroethylene(TCE)in mice.

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  • 目的研究甲醛联合染毒小鼠脾脏胸腺淋巴细胞DNARNA合成影响

    Objective To explore the effect of combined exposure of formaldehyde and benzene on DNA and RNA synthesis in spleen and thymic lymphocytes in mice.

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  • 结论亚急性BHT剂量染毒造成大鼠肝等脏器功能性器质性损伤,BHT诱发细胞凋亡的产生。

    Conclusion BHT may cause functional and organic damage of lung and liver, and it can induce apoptosis to pulmonary macrophage in rats.

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  • 结果随着染毒时间延长,腰髓前角神经细胞膜上的嵌入蛋白质由分布紊乱成簇聚集

    Results: as the extending of inhaling time inserting proteins distribution changed from turbulence to cluster.

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  • 染毒时间延长,同一染毒剂量组内细胞增殖活性变化率有下降趋势一定染毒时间-效应关系

    Cell proliferation rate declines with the prolongation of exposure time to DMF, and time-effect relationship exists.

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  • 随着TOCP染毒时间延长细胞mdaCAT含量均呈明显的时间—效应关系

    With the TOCP treatment time prolonged, intracellular MDA and CAT levels showed obvious time-effect relationship.

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  • 高剂量染毒组动物主动脉弓、心肌、和大脑皮质透射电镜观察结果显示:主动脉弓内皮细胞出现肿胀细胞变形部分染色质溶解、染色质聚现象;

    The endothelial cells of aortic arch were swelling, the nuclei of which was twisted, a part of chromatin was dissolved and migrated to the cell edge.

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  • 染毒细胞突起结构逐渐消失细胞体积变小、形态变圆。

    After the treatment of rotenone cell ecptomas vanished gradually and cell bodies became smaller and smoother.

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  • 采用流式细胞术检测,G2/M细胞百分数增加,1/50LD50染毒时与对照组比较差异具有显著性(P<0.05)。

    The percentage of cells at G2/M phase was increased with the increasing of MeHg, and the 1/50 LD50 group had significant difference compared with control group (P<0.05).

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  • 目的研究HSP70乐果染毒U87细胞中的保护作用

    [Objective] To investigate the protective effect of HSP70 in U87 cell line treated with dimethoate.

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  • 目的]观察香烟烟雾染毒致胎鼠眼畸形作用及对视杯、视泡上皮细胞间充质细胞凋亡的影响

    Objective To study the affection of the hyperthmia and cigarette smoking on the neonate rats neurobehavioral.

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  • 目的]观察香烟烟雾染毒致胎鼠眼畸形作用及对视杯、视泡上皮细胞间充质细胞凋亡的影响

    Objective To study the affection of the hyperthmia and cigarette smoking on the neonate rats neurobehavioral.

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