• 对该基因表达抑制引起成肌细胞过度增殖肌纤维肥大从而引起骨骼肌增生

    The inhibition of Myostatin expression can accelerate the myoblast proliferation and myofibril hypertrophy, which results in the skeletal muscle hyperplasia.

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  • 目的研究携带血管抑素K1-5基因腺病毒载体对其血管内皮细胞增殖抑制作用

    Objective To investigate the suppression effects of a adenovirus vector containing angiostatin K1-5 gene to the proliferation and migration of vascular endothelial cells.

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  • 目的探讨E1A基因细胞增殖抑制作用细胞周期关系及作用机制。

    Objective To investigate the effects of E1A gene on the proliferation rate and the cell cycle of human lung adenoma cell line.

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  • 结论:利用RNA干扰PPO基因反面证实PPO增殖磷酸化有关,并且细胞水平活体水平,均证实能够抑制卵巢癌细胞的生长。

    Conclusion: it is identified that the PPO gene relates to proliferation and phosphorylation from reverse and the ovarian cancer cells can be suppressed by RNA interference from in vitro to in vivo.

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  • 结论TJU103不仅可以显著抑制体外t淋巴细胞增殖效应,而且显著降低小鼠同种基因造血细胞移植模型GVHD发生率

    Conclusion TJU103 is capable of markedly inhibiting t cell proliferative response in vitro and can decrease GVHD incidence after allogeneic stem cell transplantation in mice.

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  • 目的研究B71基因小鼠前胃癌细胞MFC增殖活性抑制作用,探讨其在肿瘤免疫中的作用。

    OBJECTIVE:To investigate the suppression effect of B7 1 gene on proliferous characteristics of MFC cells.

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  • 研究发现SPATA4基因能够抑制细胞衰老细胞凋亡促进细胞周期推进细胞增殖

    This research reveals that SPATA4 gene can inhibit cellular senescence and apoptosis as well as promote the progression of cell cycle and cell proliferation;

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  • 结论胃癌细胞导入外源性FHIT基因可以抑制肿瘤细胞增殖诱导细胞凋亡引起细胞生长周期阻滞

    Conclusions: Transfecting the exogenous FHIT gene into gastric cancer cells can suppress the proliferation of tumor cells, and can also induce apoptosis and cell cycle arrest.

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  • 结论CD70基因肝癌中呈阳性表达,抑制淋巴细胞增殖活性,在肝癌细胞免疫逃逸重要作用

    ConclusionThe CD70 gene is expressed in hepatocellular carcinoma and can inhibit the proliferation of lymphocytes. The CD70 gene may play an important role in the immune escape of hepatoma cells.

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  • HBP1通过抑制细胞增殖基因mif表达抑制肿瘤细胞生长

    HBP1 inhibition of cancer cells growth is achieved at least partially by suppressing MIF expression.

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  • 大鼠模型中,表达EPO基因质粒组血清明显中和活性抑制BEF-2细胞增殖

    The serum from anemic rats treated with naked plasmid expressing human EPO showed obvious neutralizing activity to inhibit the proliferation of BEF-2 cells.

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  • 结论:稳定表达人ox40l的乳腺癌转基因细胞体外有效地活化t细胞,介导增殖分泌细胞因子抑制T细胞活化诱导的细胞死亡

    CONCLUSION: OX40L-MDA-MB-435 cells could activate t cells in vitro, promote t cell proliferation and cytokine secretion, and suppress t cell activation-induced cell death.

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  • 结论:稳定表达人ox40l的乳腺癌转基因细胞体外有效地活化t细胞,介导增殖分泌细胞因子抑制T细胞活化诱导的细胞死亡

    CONCLUSION: OX40L-MDA-MB-435 cells could activate t cells in vitro, promote t cell proliferation and cytokine secretion, and suppress t cell activation-induced cell death.

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