对该基因表达的抑制可引起成肌细胞的过度增殖和肌纤维的肥大,从而引起骨骼肌增生。
The inhibition of Myostatin expression can accelerate the myoblast proliferation and myofibril hypertrophy, which results in the skeletal muscle hyperplasia.
目的研究携带血管抑素K1-5基因的腺病毒载体对其对血管内皮细胞增殖的抑制作用。
Objective To investigate the suppression effects of a adenovirus vector containing angiostatin K1-5 gene to the proliferation and migration of vascular endothelial cells.
目的探讨E1A基因对人肺腺癌细胞增殖的抑制作用与细胞周期的关系及作用机制。
Objective To investigate the effects of E1A gene on the proliferation rate and the cell cycle of human lung adenoma cell line.
结论:利用RNA干扰PPO基因,从反面证实PPO与增殖和磷酸化有关,并且从细胞水平到活体水平,均证实能够抑制卵巢癌细胞的生长。
Conclusion: it is identified that the PPO gene relates to proliferation and phosphorylation from reverse and the ovarian cancer cells can be suppressed by RNA interference from in vitro to in vivo.
结论TJU103不仅可以显著抑制体外t淋巴细胞增殖效应,而且可显著降低小鼠同种异基因造血干细胞移植模型GVHD的发生率。
Conclusion TJU103 is capable of markedly inhibiting t cell proliferative response in vitro and can decrease GVHD incidence after allogeneic stem cell transplantation in mice.
目的:研究B71基因对小鼠前胃癌细胞(MFC)增殖活性的抑制作用,探讨其在肿瘤免疫中的作用。
OBJECTIVE:To investigate the suppression effect of B7 1 gene on proliferous characteristics of MFC cells.
本研究发现SPATA4基因能够抑制细胞衰老和细胞凋亡、促进细胞周期的推进与细胞增殖;
This research reveals that SPATA4 gene can inhibit cellular senescence and apoptosis as well as promote the progression of cell cycle and cell proliferation;
结论:向胃癌细胞中导入外源性FHIT基因可以抑制肿瘤细胞增殖,诱导细胞凋亡并引起细胞生长周期阻滞。
Conclusions: Transfecting the exogenous FHIT gene into gastric cancer cells can suppress the proliferation of tumor cells, and can also induce apoptosis and cell cycle arrest.
结论CD70基因在肝癌中呈阳性表达,并可抑制淋巴细胞的增殖活性,在肝癌细胞免疫逃逸中起了重要作用。
ConclusionThe CD70 gene is expressed in hepatocellular carcinoma and can inhibit the proliferation of lymphocytes. The CD70 gene may play an important role in the immune escape of hepatoma cells.
HBP1通过抑制促细胞增殖基因mif的表达抑制肿瘤细胞生长。
HBP1 inhibition of cancer cells growth is achieved at least partially by suppressing MIF expression.
在大鼠模型中,表达人EPO基因裸质粒组的血清有明显的中和活性,可抑制BEF-2细胞的增殖。
The serum from anemic rats treated with naked plasmid expressing human EPO showed obvious neutralizing activity to inhibit the proliferation of BEF-2 cells.
结论:稳定表达人ox40l的乳腺癌转基因细胞在体外能有效地活化t细胞,介导其增殖、分泌细胞因子及抑制T细胞活化诱导的细胞死亡。
CONCLUSION: OX40L-MDA-MB-435 cells could activate t cells in vitro, promote t cell proliferation and cytokine secretion, and suppress t cell activation-induced cell death.
结论:稳定表达人ox40l的乳腺癌转基因细胞在体外能有效地活化t细胞,介导其增殖、分泌细胞因子及抑制T细胞活化诱导的细胞死亡。
CONCLUSION: OX40L-MDA-MB-435 cells could activate t cells in vitro, promote t cell proliferation and cytokine secretion, and suppress t cell activation-induced cell death.
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