HMGB1与纤维蛋白酶原、基质金属蛋白酶的活化、细胞骨架重组等有关。
HMGB1 plays roles in activation of plasminogen and matrix metalloproteases, reorganization of cytoskeleton.
背景：溶纤维蛋白酶抑制剂已经证明，以减少骨外科术中主要相关步骤的出血。
Background: Antifibrinolytic agents have been shown to decrease the blood loss associated with major orthopaedic surgical procedures.
蛇毒类凝血酶属于纤维蛋白原裂解酶，是一种丝氨酸蛋白酶。
Snake venom thrombin-like enzymes belong to the fibrinogenolytic enzyme family and are serine proteases.
研究了大豆胰蛋白酶抑制剂（STI）对鲢肌肉中肌原纤维结合型丝氨酸蛋白酶（MBSP）引起的肌原纤维蛋白降解作用的影响。
The effect of soybean trypsin inhibitor (STI) on the degradation of silver carp myofibrillar proteins caused by an endogenous myofibril-bound serine proteinase (MBSP) was studied.
研究者还发现2型纤维蛋白溶酶原激活因子抑制物(PAI2)(一种丝氨酸蛋白酶抑制物)抑制结核杆菌感染的巨噬细胞内的膜联蛋白- 1的蛋白水解作用。
The researchers also found that plasminogen activator inhibitor type 2 (PAI2), a serine-protease inhibitor, inhibited proteolytic truncation of annexin-1 in macrophages infected with M. tuberculosis.
研究者还发现2型纤维蛋白溶酶原激活因子抑制物(PAI2)(一种丝氨酸蛋白酶抑制物)抑制结核杆菌感染的巨噬细胞内的膜联蛋白- 1的蛋白水解作用。
The researchers also found that plasminogen activator inhibitor type 2 (PAI2), a serine-protease inhibitor, inhibited proteolytic truncation of annexin-1 in macrophages infected with M. tuberculosis.
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