端粒是高度重复的，从基因上来说没有意义的DNA序列，我们称之为垃圾 DNA。
Now a telomere is a highly repetitious and genetically meaningless sequence of DNA, what we were calling junk DNA.
无论如何，如果我们检查这些螺旋状DNA的末端，我们会发现每条人类染色体的末端都有一个被称作“端粒”的 DNA序列。
Anyway, if we examine these ends of these coils of DNA, we will find a sequence of DNA at each end of every human Chromosome, called a telomere.
该团队取得了突破性的成功，他们确定了个体身上有个基因序列与端粒的长短密切相关。
In a significant breakthrough, the team successfully identified that a particular gene sequence was associated with differences in telomere length between individuals.
布莱克本和绍斯塔克发现，端粒中一种独特的DNA序列能保护染色体免遭老化。
Blackburn and Szostak discovered that a unique DNA sequence in the telomeres protects the chromosomes from degradation.
布莱克本和卓斯塔克测定，端粒中一段特殊的DNA序列在细胞分裂染色体自我复制时保护了染色体免受损耗。
Blackburn and Szostak determined that it was a specific DNA sequence in the telomeres that kept chromosomes from fraying whenever they were copied when a cell splits in two.
伊丽莎白·布莱克本和杰克·卓斯塔克发现，由于端粒上有独特的DNA序列，从而能防止染色体的退化。
Elizabeth Blackburn and Jack Szostak discovered that a unique DNA sequence in the telomeres protects the chromosomes from degradation.
通过对血液样本的分析，Samani教授和Spector教授发现，有些人具有与其年龄不相称的过短染色体端粒，而一种特定的基因序列在这些人中更常见。
From blood samples, Samani and Spector found a particular gene sequence was more common in people who had unusually short telomeres for their age.
RNA包含CCCCAA序列，其是制造端粒的模板，而蛋白质则为酶活性提供所需的物质。
The RNA contained the CCCCAA sequence which acted as a "template" for building telomeres, while the protein supplied the material for the enzymatic activity.
它是通过重组其它染色体上的DNA序列来加长端粒的，我们对其研究的并不透彻。
The less understood ALT pathway lengthens telomeres through recombination with DNA sequences from other chromosomes.
目的：建立端粒重复序列扩增(TRAP)-银染色技术，探讨端粒酶活性检测在肿瘤诊断中的意义。
Objectives: to establish a method of telomere repeat amplification protocol (TRAP) silver stain technique, and to investigate the significance of telomerase activity detection in tumor diagnosis.
方法取19例颅内肿瘤和5例脑外伤患者脑脊液标本，应用改良的银染端粒重复序列扩增法(TRAP)进行端粒酶活性检测。
Methods a modified telomeric repeat amplification protocal (TRAP) by silver staining was performed in 19 cases of intracranial tumors and 5 cases of brain injuries.
用端粒重复序列扩增法（TRAP）半定量方法测定细胞染毒前后端粒酶活性的变化；
The changes of telomerase activity after treatment was detected and quantified by telomeric repeat amplification protocol (TRAP) semi_quantitative analysis.
细胞染色体末端具有特殊序列，该序列具有维持染色体稳定的功能，被命名为“端粒”。
The specific structure at the end of the chromosome named "telomere" is essential for chromosome stability.
端粒重复序列扩增酶联免疫吸附法测定端粒酶活性；
Telomerase activity was also examined by telomeric repeat amplification protocol enzyme-linked immunosorbent assay (TRAP-ELISA).
方法采用端粒重复序列扩增法一酶联免疫（PCR-TRAP）检测70例肺癌手术患者癌组织中的端粒酶活性，并与70例肺部良性疾病患者对照组的检测结果进行比较。
Methods Use PCR-TRAP detection of 70 cases of lung cancer patients' telomerase activity in cancer tissue. and 70 patients with benign lung disease and the results were compared.
通过对它的研究，人们发现并且掌握了核酶的分子机制、RNA的自我拼接、端粒的结构和功能、DNA序列重组等机理。
Some investigations on the ciliated protozoan have provided the insights into the mechanism of ribozymes, self-splicing RNA, telomere structure and function, DNA sequence reorganization and so on.
方法采用端粒重复序列扩增文件-酶标法（TRAP-ELISA）测定尖锐湿疣皮损中端粒酶的活性，并与正常皮肤和恶性肿瘤对照比较。
Methods The telomerase activity was detected by TRAP( telomeric repeat amplification protocol) -ELISA which based upon PCR amplification of the initial telomerase product and detected by ELISA.
端粒是保护染色体末端的非编码重复DNA序列。
Telomeres are sections of noncoding, repeating DNA that protect chromosome ends.
端粒是染色体末端的特化结构，由简单呈串联线性排列的核酸重复序列及相关蛋白质组成。
Telomeres, the specialized structure of chromosomes ends, consist of tandem arrays of DNA repeats and related proteins.
端粒酶（网站链接 ）包含一个重要的核糖核酸成分，是补充端粒重复序列。
The telomerase ( web link ) contains an essential RNA component which is complementary to the telomere repeat sequence.
端粒酶是真核生物中一种逆转录酶，它能将端粒区的g重复序列加到染色体末端以维持端粒长度的稳定。
Telomerase is a ribonucleoprotein enzyme maintaining the length of the telomeres by adding G-rich repeats to the end of the eukaryotic chromosomes.
方法：采用端粒重复序列扩增文件酶标法（TRAP-ELISA），对32例AML和非恶性血液系统疾病骨髓细胞端粒酶活性检测。
Methods:The telomerase activity was determined in bone marrow cells from 32 patients of acute myeloid leukemia and non-malignant hematogic disease by TRAP-ELISA.
方法：采用端粒重复序列扩增文件酶标法（TRAP-ELISA），对32例AML和非恶性血液系统疾病骨髓细胞端粒酶活性检测。
Methods:The telomerase activity was determined in bone marrow cells from 32 patients of acute myeloid leukemia and non-malignant hematogic disease by TRAP-ELISA.
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