看起来正在发生的是,这些认知刺激确实抵消了跟老年痴呆症有关的神经变性的机能障碍。
What seems to be happening is that cognitive stimulation helps overcome the effect of the neurodegenerative lesions associated with dementia.
机体过量的锰暴露会导致进行性、持久性和神经变性的损害,严重者出现帕金森氏病样症状。
Overexposure to manganese can lead to progressive, permanent, neurodegenerative damage, resulting in syndromes similar to idiopathic Parkinson s disease.
RoyFreeman教授:基于临床前研究的数据和最近的临床资料,有许多生化途径在神经变性的功能障碍中发挥着关键作用。
Prof Roy Freeman: There are a number of biochemical pathways based on preclinical data and more recently clinical data which play a key role in dysfunction of nerve degeneration.
老年痴呆症是一种十分严重的大脑神经变性失调症,其特点是记忆丧失和认知衰退。
Alzheimer's disease is a severe neurodegenerative disorder of the brain that is characterized by loss of memory and cognitive decline.
在期刊的分子神经变性一文中,科学家指出,痴呆症对脑部的破坏“或许可以通过健康饮食来调理,甚至是清除。”
Scientists say the findings, published in the journal Molecular Neurodegeneration, suggest the ravages of dementia "might be slowed or avoided through healthy eating".
他们提出这些发现有助于找到治疗青光眼及其它神经变性疾病的新方法。
They suggested that these findings open the door to new treatments for glaucoma and perhaps other neurodegenerative diseases as well.
和许多神经变性疾病一样,典型的病人从20岁到50岁之间开始出现病症,而随着时间推移症状进行性加重。
As with many neurodegenerative diseases, patients typically begin to show symptoms during their mid-20s to mid-50s, and the symptoms grow progressively more debilitating with time.
这一发现暗示了治疗诸如阿尔茨海默病等神经变性疾病的方法,并使得我们对大脑功能的了解更为全面。
This finding has implications for the treatment of neurodegenerative diseases such as Alzheimer's Disease and our understanding of brain function more generally.
癫痫,慢性疼痛,神经变性疾病,和肌肉疾病可能都涉及到离子通道的突变,并且离子通道是许多药物的靶点。
Mutations in ion channels are likely to be involved in epilepsy, chronic pain, neurodegenerative diseases and muscular diseases, and ion channels are the target of many drugs.
大约十年间,科学家们一直尝试利用干细胞使神经退变性疾病中的神经细胞再生,例如帕金森病,阿尔茨默病和肌萎缩侧索硬化。
For around a decade, scientists have been trying to regrow nerve cells lost in neurodegenerative diseases such as Parkinson's, Alzheimer's and amyotrophic lateral sclerosis (ALS) from stem cells.
ALS是一种致命的神经变性情况,100,000中就有1 -2人受其影响,发病率随年龄增加而增长。
ALS is a fatal neurodegenerative condition that affects about 1 to 2 per 100,000 people. Its incidence increases with age.
目的报道一个五代母系遗传的未知神经变性疾病家系。
Objective To report a five-generation Chinese family with unidentified maternally transmitted hereditary neurodegenerative disease.
ALS是由运动神经元的变性和死亡而发生的,该运动神经元可将神经冲动从脊髓传达到身体的各块肌肉。
ALS is caused by the degeneration and death of motor neurons, the nerve cells which convey nerve impulses from the spinal cord to each of the body's muscles.
所有的患者均由确定RBD、行为神经学或运动紊乱的睡眠医学专家进行评估,以确定后来的神经变性症状。
All patients underwent evaluations by specialists in sleep medicine to confirm RBD, and behavioral neurology or movement disorders to confirm the subsequent neurodegenerative syndrome.
也有证据表明存在一个自主神经机能异常的前期,与发生于患者脑干中的神经变性过程延长并存。
There is also evidence for a prior period of dysautonomia, which is in keeping with a protracted neurodegenerative process occurring within the brainstem of these patients.
RBD发病到神经变性症状出现之间的间隔范围是15 ~50年,中位值为25年。
The median length of time between RBD onset and neurodegenerative symptoms was 25 years, ranging from 15 to 50 years.
目的:探讨大鼠坐骨神经变性轴突清除中的自噬作用。
Objective: to investigate the autophagic role of neuron axon during regeneration of rat sciatic nerves.
这些包括预防疾病,如神经变性,肿瘤等,发现疾病,个性化的医疗诊断和监测等。
These include prevention of diseases such as neural degeneration, cancer, etc., detection of diseases, personalized medical diagnostics and monitoring among others.
结论:CT不仅能诊断腰椎退变性滑脱症,而且还能显示硬膜囊和神经根的改变。
Conclusion: CT can not only diagnose lumbar degenerative spondylolisthesis but also show the changes of dural sacs and nerve roots.
一些神经营养因子也可以保护变性疾病中的易损神经元,维持其正常功能的发挥。
Some neurotrophic factors can also protect the vulnerable neurons and support their normal function in the degenerative disease.
结论:内源性兴奋毒对未成熟脑创伤性神经元变性起十分重要的作用。
Conclusion: Excitotoxic may be an important mechanism for trauma-induced neurodegeneration in immature brain.
白质小动脉缺血导致神经胶质细胞变性和白质纤维髓鞘脱失是发生白质疏松的主要原因,它可能导致或加重智能障碍。
The main reason responsble to leukoaraiosis was ischemia in white matter leading to neuroglia degeneration and demyelination. Leukoaraiosis may cause or deteriorate disturbance of intelligence.
目的:以银浸染法显示神经组织培养中的变性纤维。
Objective: To show degenerated fibers in nerve tissues culture by silver impregnation method.
提示老年黄斑变性的患者,不仅有黄斑区损害,可能在视神经至视觉中枢也存在类似的老年变性改变。
The results suggest that aging degeneration exists in macular area, and similar lesion may occur coincidentally from optic nerve to visual centre.
结果结肠慢传输型便秘的病理检查可见肠壁神经丛有变性、减少。
Results Pathological findings suggested the nerve plexus in the intestinal wall of STC degenerated and decreased.
目的探讨亚急性联合变性(SCD)患者中枢神经系统(CNS)功能受累的部位。
Objective To localize the functional involvement of the central nervous system (CNS) in patients with subacute combined degeneration (SCD).
电镜下可见铁处理大鼠神经突起空泡变性,空泡化的细胞核周线粒体变性及微管堆积。
Under electron microscope, vacuolate degeneration of neuronal processes with mitochondria degeneration and accumulation of microtubule near vacuolar nucleus were observed in iron treated rats.
这些系统降解错折叠和聚集蛋白的功能改变在比如帕金森病的许多神经变性疾病中起关键作用已逐渐被认识。
Dysfunction of the UPS has been already strongly implicated in the pathogenesis of this disease and, more recently, growing interest has been shown in identifying the role of ALP in neurodegeneration.
这些系统降解错折叠和聚集蛋白的功能改变在比如帕金森病的许多神经变性疾病中起关键作用已逐渐被认识。
Dysfunction of the UPS has been already strongly implicated in the pathogenesis of this disease and, more recently, growing interest has been shown in identifying the role of ALP in neurodegeneration.
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