最后我们选用异二丙胺锂(LDA)为碱,在干冰丙酮浴下,合成了烯醇磷酸酯,并有很高的立体选择性。
At last , we used the base: LDA, dry ice-acetone bath , to synthesize the enol phosphates and gain very high rigio-selectivity.
通过添加适量四丁基溴化铵为相转移催化剂,使用过量的亚磷酸二异丙酯以补偿其在强碱环境中的水解,从而提高了反应产率。
The yield was increased through adding tetrabutyl ammonium bromide as the phase transfer catalyst, and using excessive diisopropyl phosphite to compensate its hydrolyzation.
通过添加适量四丁基溴化铵为相转移催化剂,使用过量的亚磷酸二异丙酯以补偿其在强碱环境中的水解,从而提高了反应产率。
The yield was increased through adding tetrabutyl ammonium bromide as the phase transfer catalyst, and using excessive diisopropyl phosphite to compensate its hydrolyzation.
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