目的观察原癌基因表达在哮喘气道重塑中的作用。
AIM to explore the role of proto oncogenes in the process of airway remodeling in asthma.
结论:MET原癌基因表达水平与食管鳞癌细胞分化相关。
Conclusion: The mRNA overexpression of MET proto-oncogene is correlated with tumor differentiation in ESCC.
目的:从基因水平了解正常胃和胃癌组织原癌基因和抑癌基因表达的分子机制。
Objective: To study the expressions of pro-onc and tumor suppressor genes in gastric cancer by cDNA expression array.
目的:探讨肝癌患者外周血淋巴细胞染色体脆性部位与原癌基因表达率的相关性。
Objective to explore the correlation between chromosome fragile site in peripheral blood lymphocytes and proto-oncogene expression rate in patients with hepatocellular carcinoma.
目的应用基因微矩阵技术分析原发性食管癌基因表达谱,筛选与食管癌进展相关基因。
OBJECTIVE: This study was to investigate the differentially expressed genes between primary esophageal squamous cell carcinoma and normal esophageal mucosa using cDNA microarray.
中医药在抑制血管生成、促进细胞凋亡、调节内分泌系统和抑制癌基因表达方面对癌前病变的干预作用。
Traditional Chinese medicine (TCM) has shown effects on precancerous changes through inhibiting angiogenesis, promoting apoptosis, modulating endocrine system and restraining oncogene expression.
其作用机理为抗氧化作用,抗细胞增殖,诱导细胞调亡,干预细胞转导和增强抑癌基因表达,干预细胞周期等。
The mechanism are antioxidation, cell proliferation suppression, apoptosis induction, cell signal transduction disturbing and tumor suppression gene activity enhancing, cell cycle disturbing etc.
同样,在公开的乳腺癌基因表达数据库中,SF3B 3过表达与总生存率显著相关,SF 3b1则无此作用。
Similarly, in publicly available breast cancer gene expression data sets, overexpression of SF3B3, but not SF3B1, was significantly correlated with overall survival.
抑癌基因p53编码转录因子p53蛋白在调控癌基因表达、dna合成和损伤修复以及细胞凋亡中起关键作用。
The tumor suppressor gene p53 codes for a transcription factor, p53 protein, plays a critical regulation role in oncogene expression, DNA synthesis and repair systems, and cell apoptosis.
利用随机矩阵理论(RMT)方法除去肺癌基因表达数据中的噪声,并将去噪后的数据分别用模块方法和等级聚类方法进行处理。
We used random matrix theory (RMT) to remove the noises in lung cancer gene expression data and used the modules approach and the hierarchical clustering approach to construct the gene networks.
虽然许多原癌基因和肿瘤抑制基因被广泛表达,这些基因的突变与特定的器官或细胞类型的癌有关。
Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.
VEGF121的表达受到组织缺氧,炎症因子和肿瘤组织产生的致癌基因的诱导(1-3)。
VEGF121 expression is induced by hypoxia, inflammatory cytokines and through oncogene products in tumors (1-3).
初始细胞的癌基因的表达往往会通过诱导细胞凋亡、衰老来阻止细胞的增值的,而其实现上述功能的具体途径仍有待澄清。
Expression of an oncogene in a primary cell can, paradoxically, block proliferation by inducing senescence or apoptosis through pathways that remain to be elucidated.
FHIT是一种重要的抑癌基因,在多种肿瘤中被发现表达缺失。
FHIT is an important tumor suppressor gene, in a variety of tumors expression was found missing.
同一种原癌基因在不同种动物生精周期的相同阶段表达也不尽相同。
In different kinds of animals, the same proto_oncogene showed different expressions in the same phase of spermatogenic cycle.
人抑癌基因,其编码的蛋白,含有其的表达载体和由该载体转化的细胞。
Human cancer suppressor gene, protein encoded therein, expression vector containing the same, and cell transformed by the vector.
程序性细胞死亡因子4 (PDCD4)基因是首先在细胞凋亡中因一种表达特异的蛋白质而鉴别出来的一种新的抑癌基因。
Programmed cell death factor 4 (PDCD4) gene is a new anti-oncogene, which is firstly identified as a specific protein expressed in cell apoptosis.
目的:探讨骨肿瘤复发后组织起源及相关癌基因蛋白表达的变化。
Objective: to investigate the changes in histogenesis and expressions of related oncogene protein in recurrent bone tumor.
目的探讨抑癌基因pten蛋白在大肠癌的表达及临床意义。
Objective To explore the expression and clinical significance of PTEN gene in large intestine carcinoma.
而某些癌基因和抑癌基因对HIF-1表达及活性的影响最终决定着肿瘤的预后。
The influencing of some oncogene and anti-oncogene to the expression and activity of HIF-1 determines neoplastic prognosis ultimately.
目的探讨抑癌基因DPC4和PTEN蛋白在大肠癌的表达及临床意义。
Objective To explore the expression and clinical significance of PTEN and DPC4 gene in large intestine carcinoma.
免疫组化检测癌基因蛋白表达。
The protein expression of oncogene was assayed with immunohistochemistry.
结论:胃炎康加维酶素可能是通过抑制胃黏膜癌基因蛋白的异常表达而发挥治疗胃癌前病变的作用。
Conclusion:The effect of Weiyankang plus gastrone on precancerosis of gastric cancer may due to repress the abnormal expression of oncogene proteins in gastric mucosa.
胃癌的发生与多基因异常表达密切相关,其中抑癌基因甲基化是胃癌发生、展的重要机制之一。
The genesis of gastric cancer resulted from abnormal expression of many genes, and methylation of the tumor suppressor genes is one of the major mechanisms of gastric carcinogenesis.
目的:检测癌基因d52家族新基因PC - 1在细胞周期各时相的表达变化。
Objective: To investigate the expression of PC-1, the new gene of tumor protein D52 family, during cell cycle.
目的体外构建和表达可调控性人抑癌基因pten重组腺病毒。
Objective to construct and express a recombinant adenovirus vector which can regulate expression of human tumor suppressor gene PTEN.
目的:本文研究癌基因stk15在喉鳞状细胞癌中的表达情况,探讨STK15与喉鳞状细胞癌的相关性。
Objective: to investigate the expression of oncogene STK15 in laryngeal squamous cell carcinoma, to find out the correlation of STK15 and laryngeal squamous cell carcinoma.
目的探讨癌基因蛋白表达在骨巨细胞瘤生物学行为与预后方面的意义。
Objective to study the correlation of expression of oncogene proteins with the invasion and recurrence of giant cell tumor (GCT) of bone and its various cytologic grades.
目的探讨抑癌基因pten在脑胶质瘤组织中的表达情况及其临床意义。
Objective to investigate the expression of tumor suppressor PTEN mRNA in human glioma and to elucidate its clinical significance.
目的探讨抑癌基因pten在脑胶质瘤组织中的表达情况及其临床意义。
Objective to investigate the expression of tumor suppressor PTEN mRNA in human glioma and to elucidate its clinical significance.
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