RNA病毒作为疫苗载体,在可操作性和免疫效果方面有着显著的优势,近年来已成为疫苗研究领域的热点。
Using RNA virus as vaccine vector are becoming hotspots in the field of vaccine research these years for their prominent advantages such as easy manipulation and high efficiency.
杆状病毒载体将在未来药物研发、疫苗生产、基因治疗、重组杆状病毒杀虫剂等领域得到广泛应用。
The insect baculovirus, in the new century, will be applied in drug research and development, production of vaccines, gene therapy and recombinant baculovirus insecticides.
本发明提供了一种新尼古丁衍生物形式的半抗原,所述半抗原可适当地与合适的载体缀合以得到针对尼古丁成瘾的有效疫苗。
The present invention provides a hapten in the form of a novel nicotine derivative that may suitably be conjugated with an appropriate carrier to yield an effective vaccine against nicotine addiction.
目的研究壳聚糖纳米粒作为蛋白类疫苗的新载体,并评价其鼻腔给药后所产生的免疫效果。
OBJECTIVE to prepare Chitosan nanoparticles (NPs) as new carriers for vaccine delivery and to evaluate the effect of this system on the immune response for intranasal delivery.
可生物降解微球作为鼻腔免疫疫苗的载体有延长免疫时间、增强免疫作用等优点。
As a delivery system for nasal immunization vaccines, biodegradable microspheres have several advantages such as extending immunization time and enhancing immune response.
在艾滋病疫苗中拓展并合理利用载体可以优化疫苗,而弄清复制型载体与非复制型载体之间的优先次序问题也十分关键。
In the AIDS vaccine development and the rational use of vector vaccine can be optimized, and copy out-Carrier and non-replicating vector between the priorities is very critical.
近年来,基因工程疫苗如重组亚单位疫苗,细菌载体疫苗等新型疫苗的研究具有广泛应用前景。
Nowadays, genetic engineering vaccines such as recombinant subunit vaccines, bacterial deliver system vaccines have an extensive prospect in clinical applications.
默克疫苗的失败至多代表非复制型腺病毒载体疫苗的失败,决不代表其他艾滋病疫苗就没有希望。
The failure of the Merck vaccine up on behalf of the non-replicating adenovirus vector vaccine failure, not on behalf of other AIDS vaccines will be no hope.
结论已成功构建了人hsp70与MAGE - 4抗原表位基因的原核表达载体,为疫苗研究提供了依据。
Conclusion the prokaryotic expression vector for HSP70 and MAGE-4 epitope genes was successfully constructed, which provided a basis for the development of vaccine.
脂质体包裹疫苗后兼有佐剂和载体的功能。
Liposome encapsulating with vaccine has the function of adjuvant and Cartier.
方法:以鸡新城疫病毒(NDV)作为疫苗模型药物、乳酸-羟基乙酸共聚物(PLGA)为载体材料,采用W/O/W复乳-溶剂挥发法制备NDV-PLGA口服微球。
METHODS:Newcastle dis-ease virus(NDV)vaccine was used as model drug, and PLGA as carrying agent to prepare NDV-PLGA oral microspheres by W/O/W emulsifying-solvent evaporation technique.
与国际上流行的艾滋病疫苗设计理念和技术路线大不相同,中国正在进行临床试验的是复制型痘苗病毒载体,属于活疫苗。
And the international AIDS pandemic vaccine design and technology very different routes, China's ongoing clinical trials is replicating vaccinia virus vector, belonging to the vaccine.
用草莓为载体生产乙肝疫苗有如下特点:(1)改变了传统人类疫苗的接种方式,以口服草莓或草莓汁的途径来接种疫苗;
There are three advantages to produce edible vaccines using strawberry: 1) It changes the inoculation mode from injection to eating strawberry or drinking the juice;
用草莓为载体生产乙肝疫苗有如下特点:(1)改变了传统人类疫苗的接种方式,以口服草莓或草莓汁的途径来接种疫苗;
There are three advantages to produce edible vaccines using strawberry: 1) It changes the inoculation mode from injection to eating strawberry or drinking the juice;
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