随着年龄的增加,源于男性的染色体疾病也有增加。
As the addition of the age, result from chromosome disease of the male also has increase.
在这八周了,这些染色体是男性胚胎和女性胚胎的唯一区别。
For a few weeks, these chromosomes are all that differentiates male embryos from female embryos.
这使只有一条X染色体的男性处于不利地位,而女性拥有两条,所以即使一条上的免疫基因不能发挥作用,另一条上的也能起到弥补作用。
This leaves men at a disadvantage since they only have one X chromosome. Women have two, so that even when immunity genes are silenced on one the other can compensate.
该病属常染色体隐性遗传,与X-染色体关联,所以,母亲是基因携带者的男性表现为发病。
The disease is autosomal-recessive and linked to the X-chromosome, so that men whose mothers are carriers of the gene manifest the disease.
要记住的是,如果男性唯一的X染色体抵御疾病,就会表现出疾病的症状。
Remember, males will show symptoms of the disease if their only X chromosome is defective.
因为男性只有一条从母亲那里遗传来的X染色体,因此他们的TEX11基因只有一个拷贝,理论上来说,TEX11基因的任何突变都可以导致不育。
Because men have only one X chromosome that they inherit from their mother and thus only one copy of the TEX11 gene, any mutation could theoretically lead to sterility.
染色体嵌合现象并不是男性与女性之间唯一的基因差别。
X chromosome mosaicism is not the only genetic difference between males and females.
目的探讨染色体的异常对男性生育能力的影响。
Objective To investigate the influence of chromosome abnormality on male reproductive ability.
几十年来,传统的理论认为X染色体与减数分裂以及男性不育无关,因为在男性减数分裂过程中X染色体被沉默掉了。
For decades, conventional wisdom stated that the X chromosome had little to do with meiosis or infertility because the X chromosome is silenced during male meiosis.
这个小组以相隔了13代的两个男性为测试对象,在其Y染色体相同区域上选取长约10, 000, 000核苷酸片段进行了测序,并计算了两者之间的差异。
The team sequenced the same piece of DNA - 10,000,000 or so letters or 'nucleotides' from the Y chromosome - from two men separated by 13 generations, and counted the number of differences.
研究人员发现,冠有法国姓氏的法兰德斯男性与至今仍生活在他们法国故乡的男性,Y染色体上带有相同的遗传标记。
The Y chromosomes in Flemish men with French surnames, the researchers found, had the same genetic markers found in men who live today in the region of France where their ancestors originated.
他们在20号染色体上发现两个新的遗传变异,它们大大增加了男性型秃发的危险。
They found two previously unknown genetic variants on chromosome 20 that substantially increased the risk of male pattern baldness.
方法采取2477例不育男性的外周血进行染色体核型分析。
Methods Karyotypes of 2477 infertile men were analyzed by chromosome G banding and C banding analysis.
结论染色体核型分析和Y染色体微缺失是男性生精障碍重要的遗传检测指标。
Conclusion chromosome Karyotypic and Y-chromosome AZF microdeletion analysis are important genetic assays for male spermatogenesis dysfunction.
但理论上ICSC有可能将一些影响男性生育的异常染色体、变异基因或其他遗传缺陷传给下一代。
But theoretically ICSC could be some affected male fertility abnormal chromosomes, mutation genetic or other genetic defects to the next generation.
目的:探讨非特发性男性不育症与Y染色体微缺失的关系。
Objective:To explore the relationship between Y chromosome microdeletion and non-idiopathic infertility in male cases with dyszoospermia.
然后,科学家们寻访到了家系中目前仍在世的男性后裔,并要求对其Y染色体进行测序。
Then the scientists tracked down living male descendants and asked to sequence their Y chromosomes.
结论染色体异常是造成男性不育的重要遗传因素。
Conclusion The chromosomal anomalies are important inheritance factor for male sterility.
在大多数国家里男人仅仅因为拥有一条Y染色体便享有在社会和法律上的特权,这样看来,担心男性的“悲催命运”般的困境似乎是在杞人忧天。
In much of the world they still enjoy social and legal privileges simply because they have a Y chromosome. So it might seem odd to worry about the plight of men.
大多数论证认为多基因会引致雄性脱发,而其中最为重要的的是雄激素受体基因,该基因位于X性染色体(对于男性来说遗传自母亲)。
Most likely there are multiple genes that contribute towards MPB, the most important of which appears to be the Androgen Receptor gene, located on the X chromosome (inherited from the mother).
目前,已有超过200种单基因遗传性疾病被认为是由X染色体连锁遗传引起的,这些疾病只影响男性胎儿。
At present, more than 200 diseases which have been identified are X-linked, these diseases only affect male fetuses.
用G-显带法对不同时期从事医用诊断X射线男性工作者的稳定性染色体畸变进行了分析,估算其累积剂量。
The stable chromosome aberrations of medical diagnostic X-ray workers were analyzed using G-banding and evaluated their accumulative doses.
男性不育原因多样,大量研究表明Y染色体微缺失与男性不育的关系密切。
Male infertility can be induced by many factors, and extensive studies have strongly indicated that Y chromosome microdeletions are closely related to male reproductive dysfunction.
Y染色体的大部分,男性特有的区域,是从父到子原封不动地遗传的。
The major portion of the Y chromosome, the male specific region, is inherited intact from fathers to sons.
前言:目的:分析研究染色体异常在男性不育中的诊断意义。
Objective: To study the diagnostic significance of chromosome abnormality in male infertility.
男子正被用于研究,因为男性的Y染色体提供详细资料,说明男性祖先。
Men are being used in the study because male Y chromosomes provide detailed information about male ancestry.
目的:研究男性原发性无精及严重少精症患者Y染色体AZF微缺失区域与临床表型的关系。
The analysis of correlation between karyotype and AZF microdeletion on Y chromosome for patients with azoospermia and severe oligozoospermia.
目的了解男性染色体异常核型对优生优育的影响。
Methods Abnormal karyotype of chromosome in 123 males were undergone cytogenetic analysis.
目的了解男性染色体异常核型对优生优育的影响。
Methods Abnormal karyotype of chromosome in 123 males were undergone cytogenetic analysis.
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