其研究结果将为合理设计新型顶体酶抑制剂,寻找男性口服避孕药奠定坚实基础。
These results provided a basis for the rational design of specific inhibitors to the target enzyme and the discovery of novel contraceptive agents with high potency.
以双盲法对22名健康男性志愿者进行青蒿琥酯片口服的耐受性和不良反应研究。
Studies on phase I clinical trials of artesunate tablet were carried out with double blind method in 22 male healthy volunteers.
目的在中国健康成年男性志愿者中,评估单次口服新型催醒药莫达芬尼片的安全性、耐受性。
Aim to evaluate the safety and tolerance of oral single-dose of wakefulness-promoting agent-modafinil in Chinese healthy volunteers.
方法采用随机二交叉设计试验,20例男性健康志愿受试者,单剂量口服受试制剂盐酸金刚乙胺颗粒和参比制剂盐酸金刚乙胺片。
METHODS A single oral dose of two preparations was given to 20 healthy male volunteers according to a randomized crossover design.
目的:研究健康男性自愿者口服国产丙硫氧嘧啶片的人体相对生物利用度及生物等效性。
AIM: To study the pharmacokinetics and relative bioavailability of propylthiouracil tablet in Chinese healthy male volunteers.
目的:建立西尼地平血药浓度的液相色谱串联质谱(LC-MS/MS)测定法,研究中国健康男性受试者口服西尼地平胶囊后的血浆药动学特点。
Objective:To establish a selective and sensitive LC-MS/MS method for the determination of cilnidipine in human plasma, and to study the pharmacokinetics in healthy volunteers.
方法18名健康男性志愿者,单剂量口服盐酸帕罗西汀片,在设计的时间点取静脉血,血药浓度采用液相色谱质谱(HPLCMS)法测定。
METHODS A single oral dose of 40 mg paroxetine hydrochloride was given to 18 healthy volunteers. The concentrations of paroxetine in plasma were assayed by HPLC-MS method.
方法18名健康男性志愿者,单剂量口服盐酸帕罗西汀片,在设计的时间点取静脉血,血药浓度采用液相色谱质谱(HPLCMS)法测定。
METHODS A single oral dose of 40 mg paroxetine hydrochloride was given to 18 healthy volunteers. The concentrations of paroxetine in plasma were assayed by HPLC-MS method.
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