结论：进行甲氨蝶呤血药浓度监测有利于掌握好甲氨蝶呤和四氢叶酸钙的救援剂量，从而保证化疗的有效性和安全性。
CONCLUSIONS: MTX serum concentration monitoring is helpful for mastering the rational rescue dosage of MTX and calcium folinate so as to ensure the efficacy and safety of the chemotherapy.
方法100例患者随机分为甲氨蝶呤组和对照组，后者服用与甲氨蝶呤外形、颜色、味道相同的安慰剂。
Methods 100 patients were randomly divided into the methotrexate group and the control group, which is taking shape with methotrexate, color, taste the same placebo.
服用甲氨蝶呤患者比不用甲氨蝶呤的CAD事件可能性降低46％。
Patients on methotrexate had 46 percent lower likelihood of CAD events than those not on methotrexate.
服用甲氨蝶呤患者比不用甲氨蝶呤的CAD事件可能性降低46％。
Patients on methotrexate had 46 percent lower likelihood of CAD events than those not on methotrexate.
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