这是该病的第一种生物学标志。
只有将来采用抑郁生物学标志的疾病机制研究才能明确哪一种假设是最贴切的”。
Only a future mechanism of disease study with a biologic marker for depression can clearly identify which of the . . . hypotheses is most pertinent.
结论血浆BDNF的水平可能为焦虑障碍疾病状态的生物学标志之一。
Conclusion Plasma BDNF level may be a useful biomarker for the state of anxiety disorders.
首先，生物学标志物有血清中的生物学标志物和组织中的生物学标志物。
Firstly, there are biomarkers in serum and secondly there are biomarkers in tissue.
目的研究肝纤维化的发生机制，寻找新的与肝纤维化相关的生物学标志物。
Objective to study the mechanism of liver fibrogenesis and to find new non-invasive biomarkers.
《国际肝病》：就生物学标志物而言，我们仍在努力发现候选的特异性肝癌标志物。
Hepatology Digest: in terms of biomarkers we are still struggling to find specific candidates for this cancer.
结果表明：P 53基因蛋白产物的高表达在食管癌的发生中是一个早期生物学标志。
It is suggested that the overexpression of P53 protein may be an early event in carcinogenesis of the esophagus.
然而，由于血清的获得越来越简便，人们将更加青睐于血清中更容易被检出的生物学标志。
However, due to the simplicity of getting a blood sample, easily testable biomarkers found in blood serum would be especially useful.
OPN可能是肿瘤形成过程中的早期分子事件，可作为监测肿瘤恶性进展的一个生物学标志。
OPN expression may be an early molecular event in the process of tumorigenesis and could be used as a biological marker to monitor the malignant process of osteosarcoma.
目的探讨外周血淋巴细胞HPRT基因突变作为筛选肿瘤高危人群的一个生物学标志的可能性。
Objective To explore the possibility of HPRT locus mutation in peripheral blood lymphocytes as a biomarker for screening those tumor susceptible people.
方法采用免疫组化染色检测乳腺癌患者骨髓中肿瘤细胞的生物学标志及骨髓血浆的u PA活性。
Methods Immunocytochemical staining was used to study the biologic markers of disseminated tumor cells, and U-PA activity of the plasma in the bone marrow was assayed in breast cancer patients.
研究显示大约30%的肝癌患者甲胎蛋白可能无任何升高，因此它并不是一个理想的生物学标志物。
It has been shown that around 30% of patients with liver cancer will not have any elevation in alpha - fetoprotein levels so this is not a perfect biomarker.
随着研究的不断深入，RUNX3基因有望成为胃癌诊断的一个特异性生物学标志物和基因治疗的靶点。
Along with the thorough research, RUNX3 may be a potential marker in the diagnosis and gene treatment of gastric cancer.
《国际肝病》：由于缺乏好的生物学标志物，甲胎蛋白在检出那些具有肝癌较高风险的患者方面有效用吗？
Hepatology Digest: Due to the lack of good biomarkers does alpha-fetoprotein have any utility in terms of detecting those who have higher risk of liver cancer?
非感染性炎症反应与感染的准确鉴别需要综合考虑临床表现、实验室检查、微生物学结果以及生物学标志物。
Differential diagnosis of non-infectious inflammation and sepsis requires integration of clinical manifestation, laboratory investigation including microbiologic results, and biomarkers.
综述了肿瘤分子流行病学和肿瘤易感基因生物学标志的研究现状，并展望了肿瘤分子流行病学研究的机遇和挑战。
We reviewed the advances of molecular cancer eipdemiology and biomarkers of cancer susceptibility gene. The chances and challenge of molecular cancer eipdemiology research were also discussed.
结论XRCC1A194W和A399 Q基因多态性与铅中毒易感性有关，可考虑作为铅中毒的重要易感性生物学标志。
Conclusion The polymorphisms of XRCC1 A194W and A399Q contribute to susceptibility to lead poisoning, which may be suggested as important biomarkers of susceptibility to lead poisoning.
就血清生物学标志物而言，我们仍在研究阶段，尽管关于GPC - 3有一些资料，但这仍不能成为其临床运用的最好时机。
As far as biomarkers in serum we are still in the searching stage although there is a little data regarding GPC-3 it is not yet ready for prime time clinical application.
分解代谢和合成代谢的失衡，是衰老的最常见症状，有可能是生物学衰老的有价值的标志。
This imbalance between the anabolic and catabolic hormones now appears to be the most common profile of aging and may be a valuable marker for biological aging.
它们的这些生物学功能是通过配体与受体结合的方式来发挥的，而CXCR3与CCR5是RA中趋化因子的标志性受体。
All of these biological effects are performed by binding of ligands to receptors. Elsewhere, CXCR3 and CCR5 are mark chemokine receptors in RA.
然后从沉积微相分析入手，研究了沉积相标志，包括地层岩石的颜色、沉积构造、粒度分布、古生物学等。
Then, beginning with the microfacies, signs of sediment facies, including rock's colour, sediment structure, granularity distribution, fossil and so on, are studied.
分子生物标志物的应用有助于我们早期识别生物学效应和易感人群，从而有利于毒物危险度评估，同时可用于发病机理和防治效果研究。
Molecular biomarkers can be used in early detection of biological effect, susceptible population, risk assessment and research on mechanism, treatment and prevention in diseases.
资料综合：脂肪组织来源干细胞与同样起源于中胚层的骨髓基质细胞不仅具有非常相似的生物学特性，而且在细胞表面标志谱的表达方面也非常相近。
DATA SYNTHESIS: There was similar bionomics of adipose tissue-derived stem cells and bone mesenchymal cells, and the cell-surface marker spectrum was also very similar.
诱导分化是指在分化诱导剂的存在下，恶性肿瘤细胞的形态、生物学或生物化学方面的诸多标志均向正常细胞的方向分化，甚至完全转变成正常细胞。
By derived differentiation, we mean that under the effect of differentiation inducer, malignant tumor cell has the tendency to differentiate to normal cell, even became normal cells.
然后，结合传统的标志层法、煤岩学及古生物学方法，对该区主要煤层进行对比。
Later in the paper, a correlation between the main coal-seams in this province is made, in combination with the traditional method of the key bed, coal petrography and palaeontology.
然后，结合传统的标志层法、煤岩学及古生物学方法，对该区主要煤层进行对比。
Later in the paper, a correlation between the main coal-seams in this province is made, in combination with the traditional method of the key bed, coal petrography and palaeontology.
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