就片剂而言,最终控制的几个主要参数为:片重、硬度、脆碎度、崩解、溶出等。
As for tablets, the parameters to be controlled finally are: weight, hardness, frangibility, disintegration and stripping.
结果压片力、颗粒含水量和颗粒强度是影响片剂抗张强度、脆碎度及释放度的主要因素。
RESULTS Tableting strength, humidity in granules and granule strength were the leading factors which affect tensile strength, fragility, dissolution percentage of tablets.
方法用均匀设计法,以片剂的硬度、脆碎度、崩解时限为指标,优选辅料配比。
Methods the ratio of excipients was optimized by using uniform design, and taking the hardness and the disintegrating time of tablet as indices.
方法用均匀设计法,以片剂的硬度、脆碎度、崩解时限为指标,优选辅料配比。
Methods the ratio of excipients was optimized by using uniform design, and taking the hardness and the disintegrating time of tablet as indices.
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