确定了制片压力、润湿剂无水乙醇和粘合剂聚乙烯吡咯烷酮为影响崩解时间和片剂硬度的主要影响因素。
The main factors that influence tablet hardness and disintegration time are wetting agent ethanol, agglutinating agent polyvinylpyrrolidone(PVP) and tablet pressure.
就片剂而言,最终控制的几个主要参数为:片重、硬度、脆碎度、崩解、溶出等。
As for tablets, the parameters to be controlled finally are: weight, hardness, frangibility, disintegration and stripping.
方法用均匀设计法,以片剂的硬度、脆碎度、崩解时限为指标,优选辅料配比。
Methods the ratio of excipients was optimized by using uniform design, and taking the hardness and the disintegrating time of tablet as indices.
方法采用正交设计法,以片剂的硬度、崩解时限为指标优选辅料配方。
Methods the combined excipients were optimized by using orthogonal design, and taking the hardness and the disintegrating time of tablet as indices.
如丸剂、片剂的外观应完整光洁、硬度适宜,无碎片,粘连、变色发霉等现象。
Such as pills, tablets should be complete and smooth appearance, hardness, suitable, no debris, adhesion, color mold and so on.
对制得的茶多酚片进行质量标准研究,该片剂外观完整光洁、色泽均匀,硬度、片重差异、崩解时限都符合标准。
The quality standard of TP tablet was investigated. The tablet had smooth faces, uniform colour, appropriate rigidity, low smash ratio, little fluctuate of tablet weight, short breakdown time.
对制得的茶多酚片进行质量标准研究,该片剂外观完整光洁、色泽均匀,硬度、片重差异、崩解时限都符合标准。
The quality standard of TP tablet was investigated. The tablet had smooth faces, uniform colour, appropriate rigidity, low smash ratio, little fluctuate of tablet weight, short breakdown time.
应用推荐