本发明公开了一种新的多肽——人类半乳糖激酶11。
The present invention discloses a novel polypeptide-human galactokinase 11.
环腺苷酸结合蛋白激酶的调节亚基:一个磷酸化蛋白激酶磷酸化酶激酶。
Cyclic AMP binds to the regulatory subunit of protein kinase A: Protein kinase A phosphorylates phosphorylase kinase.
科学家成功分离出这种小小的酶分子,基因学上称之为局部粘着激酶。
The scientists successfully identified the small enzyme molecule responsible, a gene called focal adhesion kinase.
糖酵解的关键酶——丙酮酸激酶,如果它有遗传缺陷,就导致会atp缺乏、红细胞寿命缩短和溶血性贫血。
Inherited deficiency of pyruvate kinase, a key glycolytic enzyme, causes ATP deficiency, which leads to reduced RBC life span and hemolytic anemia.
与此同时,特拉华州威尔明顿的Incyte制药公司,提出了自己的激酶抑制剂小范围试验的良结果。
Meanwhile, Incyte, a pharmaceutical company in Wilmington, Delaware, presented promising results from a smaller trial of its own kinase inhibitor. And a paper published in September by the.
而且多次从酶家族P38激酶中寻求新目标的尝试也失败了,尽管动物试验的结果比较积极。
And several attempts to carve a new target from a family of enzymes called p38 kinases have also failed, despite favourable results in animal models.
这个激酶从自我磷酸的组氨酸上转移磷酸基,因此(为什么是这样)通常是可逆的,这个激酶也作为一个去磷酸酶。
The kinase transfers the phosphate from an autophosphorylated histidine and thus (why thus?) is often reversible, with the kinase acting as a phosphatase as well.
后者以LIM范围编码了一个新奇的蛋白质激酶,并且在大脑中强烈地表达。
The latter encodes a novel protein kinase with LIM domains and is strongly expressed in the brain.
在小鼠模型中,GNA11突变诱导了自发转移性肿瘤,激活了丝裂原活化蛋白激酶途径。
Mutations in GNA11 induced spontaneously metastasizing tumors in a mouse model and activated the mitogen-activated protein kinase pathway.
肌病患者通常会有肌痛、肌无力的症状,同时血中肌酶(肌酸激酶)升高。
Patients with myopathy generally have muscle pain, tenderness or weakness, and an elevation of a muscle enzyme in the blood (creatine kinase).
因此,本研究的目的是调查金雀异黄素,一种蛋白质酪氨酸激酶抑制剂,对有急性或慢性糖尿病炎症小鼠(诱导脲佐菌素)的影响。
Therefore, the aim of this study is to investigate the effects of genistein, a protein tyrosine kinase inhibitor, on acute and chronic inflammation in diabetic mice (induced by streptozotocin).
这些药物的作用机制是阻断酪氨酸激酶启动信号级联反应,后者可以促进肿瘤细胞生长。
The drugs work by preventing an enzyme called tyrosine kinase from launching a signaling cascade that fuels tumor cell growth.
他们通过这种软件读取了186,879份论文的摘要,生成了一个最有希望用于试验的激酶目录单。
They used the software to read the abstracts of 186,879 papers and produced a list of the most promising kinases for experiments.
Cerepro被固定在一个腺病毒(一种能够携带双链形式的DNA病毒)上来传染基因,这个基因负责产生胸苷激酶这种蛋白质。
Cerepro harnesses an adenovirus, a type of virus which carries its DNA in double-stranded form, to transmit a gene responsible for the production of a protein called thymidine kinase.
它结合并激活蛋白激酶c,对很多细胞和组织产生影响(1,2)。
It binds and activates protein kinase c, causing a wide range of effects in cells and tissues (1, 2).
相反,没有GCN2激酶的小鼠没有肝重量减少,只有69%的腹部脂肪组织减少。
In contrast, the mice without the GCN2 kinase kept a steady liver mass and lost only 69 percent of the adipose tissue on their abdomens.
对有肺癌的实验鼠进行实验,研究发现依赖性蛋白激酶1 (Cdk1)让DNA停止修复。
In experiments on mice with lung tumours the researchers showed that blocking a molecule called Cdk1 also stopped DNA repair.
良好的分离纯化技术是开发纳豆激酶保健品的关键。
The proper technology in purification is a key in development nattokinase production.
目的:建立红细胞胰岛素受体酪氨酸蛋白激酶(IRTK)的活性测定法。
Objective: to establish a method of detecting insulin receptor tyrosine kinase (IRTK) activity from erythrocytes.
检测开始时、先用试剂盒提供的PKA双酰胺罗丹明110肽底物进行一个标准的激酶反应。
The assay begins with a standard kinase reaction performed in the provided reaction Buffer with a provided Bisamide Rhodamine 110 peptide substrate (PKA R110 substrate).
是一个新的肿瘤相关基因,其结构上与受体蛋白相似,具有一个蛋白激酶结构域。
Novel Oncogene with Kinase-domain (NOK) is a novel tumor-related gene, coding receptor like protein with a kinase domain.
这个基因编码一种蛋白质激酶,并受环状GMP小分子的调节。该基因以前有过研究,但不知道它有一定的睡眠调节作用。
This gene, which encodes a protein kinase and is regulated by a small molecule called cyclic GMP, has been previously studied but not suspected to play a role in sleep regulation.
链激酶和尿激酶溶栓是重要的,是天冬酰胺酶在治疗白血病细胞生长剂。
Streptokinase and urokinase are important in thrombolytics, and asparaginase is used as a cytostatic agent in the treatment of leukemia.
重组人蛋白激酶CK2可作为一种较为简便筛选和开发有效的CK 2抑制剂的分子靶点。
The recombinant human protein kinase CK2 may be used as a molecular target for simpler screening and development of more effective inhibitors of CK2.
蛋白激酶与蛋白磷酸酶在细胞信号传递中起着重要作用。
Protein kinases and phosphatases play a central role in cellular signaling.
该单克隆抗体用与人类己糖激酶i蛋白氨基酸序列对应的人工合成肽段免疫动物而制成。
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the sequence of human hexokinase I.
但ERBB3是一种假激酶,它仅通过与其他有激酶活动的蛋白相互作用才能发挥功能。
But ERBB3 is a pseudo-kinase; it functions only by binding with other proteins that have kinase activity.
但ERBB3是一种假激酶,它仅通过与其他有激酶活动的蛋白相互作用才能发挥功能。
But ERBB3 is a pseudo-kinase; it functions only by binding with other proteins that have kinase activity.
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