目的探讨辛伐他汀滴丸的体外溶出速率。
OBJECTIVE To study the dissolution rate in vitro of simvastatin pills.
本文研究了阿司匹林缓释片(S-RAT)的处方组成、制备工艺、体外溶出速率试验。
The formulation, preparation process and dissolution rate in vitro of Sustained-Release Aspirin tablets(S-RAT)were studied.
增加药物溶解度和溶出速率,是齐墩果酸新制剂研究中的主要措施。
One of the most powerful means in the development of oleanolic acid new dosage forms is to increase its solubility and drug dissolution velocity.
结果显示,桑沟湾沉积物中POC、TN和TP的再溶出速率存在明显的区域差异和季节性变化。
It was indicated the release rates of POC, TN and TP from sediment manifested obvious region diversity and seasonal variation.
结果药物的晶型消失,累积溶出速率明显增加。
RESULTS the crystal form of drug disappeared in the dispersion and the cumulative dissolution increased evidently.
结论:伊曲康唑固体分散体能明显提高伊曲康唑的溶解度及体外溶出速率。
CONCLUSION Itraconazole solid dispersion can significantly increase it's solubility and dissolution rate.
目的提高硝苯地平的体外溶出速率。
Objective To prepare nifedipine solid dispersions and investigate their dissolution rate.
目的制备葛根素-聚乙二醇-6000(PEG6000)固体分散体以增加其溶出速率和溶解度。
Objective To prepare solid dispersions of puerarin with polyethylene glycol 6000 (PEG6000) to improve its dissolution and solubility.
比较片剂和丸剂中黄芩苷的溶出速率,考察成型工艺对药物溶出的影响。
The effect of confection process on medicine dissolution was examined by comparing the dissolution rate of Baicalin in tablet and pill.
目的:考察水溶性联合载体在增加难溶性药物的溶出速率上是否优于单一载体,并制备速释型固体分散体。
Objective: to investigate whether the combined carrier is superior to the single carrier in improving dissolution of poorly insoluble water drug and prepare a fast released solid dispersion.
目的:提高尼群地平的体外溶出速率。
Objective:To improve the dissolution of nitrendipine preparation.
目的对破壁前后的蒲黄进行溶出度试验,考察破壁工艺对蒲黄中有效成分总黄酮溶出速率的影响。
Objective dissolution test was applied to study the dissolution rates of total flavones from Pollen Typhae before and after wall breaking.
方法:采用溶剂法制备固体分散体,进行溶解度、溶出速率测定,导数热重分析(DTG)。
Methods: the solid dispersion was prepared by solvent method. The solubility, the dissolution rate and the derivative thermogravimetry (DTG) were determined.
据实验条件下可溶性二氧化硅、锶溶出速率,估算出盘山地区偏硅酸型矿泉水的形成时间约为26年,锶型矿泉水形成时间约为8年。
Based on rate of SiO_2 and Sr in the test it is about 26 years to form slight Si-acidic mineral water and 8 years for Sr mineral water.
三种包膜肥在水中的养分溶出速率明显低于等养分量的普通肥在水中的养分溶出速率。
The nutrition release speed of the three coated fertilizer in the water is significantly lower than the release speed of the normal fertilizer of the same amount of nutrition.
三种包膜肥在培养基中的养分溶出速率明显低于等养分量的普通肥在培养基中的养分溶出速率。
The nutrition release speed of the three coated fertilizer in the medium is significantly lower than the release speed of the normal fertilizer of the same amount of nutrition.
结果:6厂家替硝唑片的溶出速率相差很大(P<0.01)。
Results:There were significant differences in dissolubility among the products from 6 factories(P<0.01).
前言: 目的:测定速效伤风胶囊的溶出速率。
OBJECTIVE: To study on the dissolution rate of Suxiao Shangfeng capsule in order to evaluate the capsule quality.
结论药物与载体合适比例的固体分散物明显提高其体外溶出速率。
CONCLUSION The dissolution rate of NFDP can be improved greatly by solid dispersions with proper ratio of drug and carrier.
该实验中,对片剂的位置准确地进行控制,结果表明,试验仪器中剪切力的差异可以影响溶出速率。
Experiments in which the tablet location was carefully controlled reveal that the variation of shear within the testing device can affect the measured dissolution rate.
结论依托度酸固体分散体能显著提高依托度酸的溶出速率。
Conclusion Etodolac solid dispersion can significantly increase the dissolution rate.
结果:固体分散体能加快药物的溶出速率,最佳比例为1∶7。
Results: The in vitro dissolution rates of ISDN solid dispersion were faster than ISDN.
目的采用制剂技术提高难溶性药物硝苯地平体外溶出速率。
OBJECTIVE The solid dispersion method was adopted to enhance the dissolution rate of nifedipine (NFDP) which is a poorly water-soluble drug.
方法应用RCZ-8A智能药物溶出仪测定不同厂家氟罗沙星片的溶出速率;
METHODS Dissolution of fleroxacin tablets were tested with RCZ-8A dissolution tester.
前言:目的:提高磺胺甲恶唑的体外溶出速率。
Objective: To improve the dissolution of the sulfamethoxazole invitro.
比较了阿莫西林和包合物的体外溶出速率。
The dissolution rates of amoxicillin and inclusion complex were compared.
结果固体分散物体外溶出速率明显高于机械混合物及硝苯地平原料药的体外溶出速率,且随载体比例增加而增大。
RESULTS the dissolution rate of NFDP-PVP solid dispersions was much faster than that of the physical mixtures, and tended to increase with the increase of the proportion of the carrier.
结论单点溶出度测定方法不能真正反映出缓释制剂的溶出速率,难以控制其溶出性能与内在质量。
Conclusion: it is very difficult to characterize the dissolution rate and control the dissolution performance and inherent quality of sustained-release preparation by a single-point dissolution test.
目的优化葛根素磷脂复合物的制备工艺,研究其固体分散体,提高葛根素的体外溶出速率。
OBJECTIVE to optimize preparation techniques for puerarin phytosomes and explore their solid dispersions to increase the dissolution of puerarin in vitro.
结果水透膜的速率远小于片芯中药物的溶出速率及岩白菜素渗透泵片的释药速率;
RESULTS The influx of water that passed the osmotic pump tablet was greatly less than the drug dissolution rate from tablet core and the bergenin release rate.
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