科学家现在可以克隆细胞和活化基因。
如果基因组是人类细胞部件的清单,那么某些蛋白质是生产管理者,可以依照需要激活和去活化基因。
If the genome is the parts list of the human cell, certain proteins are the production managers, activating and deactivating genes as needed.
迄今为止,截肢是如何被转变为基因活化一直像是魔法。
Until now, how amputation is translated into gene activation has been like magic.
DNA的低甲基化可能在异常组蛋白修饰的协同下引起某些T细胞基因的异常活化,导致狼疮自身免疫的发生。
DNA hypomethylation, likely to be cooperating with aberrant histone modification, may induce the activation of some t cell genes and development of autoimmunity in SLE.
结论铁合金颗粒使成骨细胞OPG基因表达下降,使破骨细胞分化、活化功能增强,这可能是导致假体松动的骨溶解机制之一。
Conclusion Titanium alloy particles decrease expression of OPG gene in human osteoblasts, and this may contribute to the differentiation of osteoclasts which may lead to the periprosthetic osteolysis.
人们很早就注意到,真核细胞中核小体核心组蛋白N-端尾部的乙酰化水平与基因活化密切相关。
It has been known for some time that the acetylation of N-termini of core histones in nucleosome is associated with gene activation.
RNA干扰是一个自然存在的机制,是机体用来使基因不活化,即把基因当作入侵的病原体。
RNA interference is a natural mechanism used by organisms to render genes inactive - presumably the genes of invading pathogens.
容纳性细胞允许转录活化蛋白的转录和翻译,其激活病毒的早期基因和溶解性周期。
Permissive cells allow the transcription and translation of the transcriptional activator protein(ZEBRA), which activates the early genes of the virus and the lytic cycle.
这种互相作用,不象是环境(细胞质)中某些因素引起基因突变或基因的活化和抑制。
It does not seem that in this interaction some factors of environment (cytoplasm) lead to the gene mutation or the activation and check of the gene.
可以认为,磁水可能通过活化调节基因,控制过氧化物酶活性,从而能提高蕃茄的抗病力。
It is considered that magnetic water maybe regulates the tene by activation and controls the activity of peroxidase which can raise the disease resistance of tomato.
因此,我们的团队决定要找出哪些讯息可以活化这些基因。
So our group set out to find the signals activate those genes.
结果从活化的人白细胞中克隆到IDO基因编码区全长,并构建了IDOEGFP融合蛋白表达载体。
Results The full-length coding sequence of IDO was cloned from activated human leukocytes and the expression vector for IDO-EGFP fusion protein was constructed.
在这个推论下,蛋白质除担负细胞结构和酵素的角色外,必定也是调控(或活化)基因表现的主要因子。
A corollary has been that proteins, in addition to their structural and enzymatic roles in cells, must be the primary agents for regulating the expression, or activation, of genes.
经磷酸化活化的丝裂原活化蛋白激酶,可参与多种细胞生命活动,如调节基因转录,诱导细胞凋亡、调节细胞周期等。
The MAPK which activated through phosphorylation involve several cell life activities, just like the control gene transcription, induce cell death, regulate cell circle and so on.
提示恶性肾肿瘤细胞中存在活化的细胞间粘附分子和血管细胞粘附分子基因,并可能影响肿瘤与宿主间的免疫反应。
These results suggest that there are active genes of ICAM-1 and VCAM-1 on malignant renal tumors and might be able to effect the host immune reaction.
甲基,细胞内小的化学基团,定位于DNA链上一定区域,像开关一样,掌管着基因的活化和关闭。
Methyls, small chemical groups within cells, latch on to certain areas along the DNA strand. The methyls serve as a kind of switch that renders genes active or inactive.
目的:研究同种异基因移植早期局部引流淋巴结和外周血t细胞的活化情况。
AIM: To study the activation of t cells from local lymph node and peripheral blood early after allotransplantation.
因此,推荐将鼠肝癌细胞代谢活化与重组基因酵母检测的方法相结合,用于环境样品中直接和间接雌激素效应物质的检测。
Therefore it is recommended to combine the yeast assay with the metabolic activation method based on H4IIE cell line to assay the direct and indirect estrogenic chemicals in environmental samples.
目的:研究舌鳞状细胞癌(TSCC)有丝分裂活化蛋白激酶(ERK)基因的表达及其与肿瘤病理分型、临床分期、颈淋巴结转移的关系。
PURPOSE: the aim of this study is to investigate the relationship between ERK1, ERK2 gene expression and tumor behavior such as invasion, metastasis in tongue squamous cell carcinoma (TSCC).
定点基因突变以及单通道夹被用于探测爪蟾卵细胞中摇动钾离子通道被去活化时的分子转移过程。
Site-directed mutagenesis and single-channel patch-clamp recording were used to explore the molecular transitions that underlie inactivation in Shaker potassium channels expressed in Xenopus oocytes.
结果建立了CHL ?3a4转基因细胞系,双核细胞微核试验证明该细胞系能代谢活化黄曲霉毒素b 1 (afb1)、杂色霉菌毒素(STC)、环磷酰胺(CPA)。
Results It was proved that a CHL 3a4 transgenic cell line was established, which could lead metabolic activation for aflatoxin B1 (AFB1), sterigmatocystin (STC) and cyclophosphamide (CPA).
目的:克隆人和小鼠的活化t细胞表达与分泌调节基因(RANTES基因)并分别构建腺病毒表达载体。
Objective: to clone the human and murine origin RANTES genes and construct the adenoviral expression vectors.
近年来,许多研究证实,血小板活化因子乙酰水解酶(PAF-AH)活性和多种心血管疾病关系密切,PAF-AH的活性和其基因型有关。
Recently, it was reported in some studys that the activity of platelet activating factor acetylhydrolase(PAF-AH) is closely related to many cardiovascular diseases.
核受体是配体活化的转录因子,能调控大量的靶基因。
Nuclear receptors (NRs) are ligand-activated transcription factors that regulate the activation of a variety of important target genes.
在正常生长条件下,热激因子处于钝化的单体状态,而当热激时,热激因子形成三聚体并与DNA结合,同时通过转录激活域的活化而激活热激基因的表达。
HSF is present in a latent state under normal conditions; it is activated upon heat stress by induction of trimerization, high affinity binding to DNA and transcriptional activity.
在正常生长条件下,热激因子处于钝化的单体状态,而当热激时,热激因子形成三聚体并与DNA结合,同时通过转录激活域的活化而激活热激基因的表达。
HSF is present in a latent state under normal conditions; it is activated upon heat stress by induction of trimerization, high affinity binding to DNA and transcriptional activity.
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