泊洛沙姆407是医药领域应用非常广泛的一种辅料。
Poloxamer 407 is used widely in the field of medicine as one kind of adjuvants.
结论泊洛沙姆407作为抗癌药物肝癌内注射的缓释载体是可行的。
Conclusion The P407 gel is an ideal sustained-release preparation vehicle for anticancer drugs and can be intrahepatically injected.
在注射给药方面，泊洛沙姆188可作为增溶剂、乳化剂以及基因药物的载体。
As a safe excipient, poloxamer 188 is often used as solubilizing agent, emulsifying agent and gene carrier in injection.
目的探讨泊洛沙姆407凝胶肝内注射的可行性，了解其肝内注射后的动态变化。
To study the feasibility of poloxamer 407(P407)gel for intrahepatic injection and to know the dynamic changes of P407 gel in liver.
结果表明，EC、HPC和泊洛沙姆等因素对药物释放有显著影响，这3种因素间不存在相互作用。
Factors such as ec, HPC and poloxamer were found to have significant effects on drug release from the SR tablets and no interactions were observed between these three factors.
目的考察壳聚糖对泊洛沙姆为基质的温敏性原位凝胶流变学特性的影响，为两者的配伍使用提供依据。
Objective To study the effects of chitosan on the rheological properties of in-situ gel composed of poloxamers in vitro.
方法：以利巴韦林作为模型药物，以17.7%的泊洛沙姆407作为凝胶基质制备具有适宜相转变温度的局部应用的体温敏感凝胶。
METHODS Ribavirin was selected as a model drug and the 17.7% poloxamer 407 was selected as the base meteral to develop a kind of in situ thermosensitive gels for ophthalmic use.
方法：以利巴韦林作为模型药物，以17.7%的泊洛沙姆407作为凝胶基质制备具有适宜相转变温度的局部应用的体温敏感凝胶。
METHODS Ribavirin was selected as a model drug and the 17.7% poloxamer 407 was selected as the base meteral to develop a kind of in situ thermosensitive gels for ophthalmic use.
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