甲基-D-天冬氨酸受体,神经节的乙酰胆碱受体。
N-methyl-D-aspartate receptor, and ganglionic acetylcholine receptor in 1 patient each.
然而,大脑中有大量门冬氨酸受体的白鼠在摄入少量酒精后,记忆力则会增强。
However, rats which did show high Numbers of NMDA receptors exhibited memory improvement when given small amounts of alcohol.
目的:探讨局灶性脑缺血再灌注损伤后谷氨酸受体NMDAR1蛋白表达的变化及意义。
AIM:To study the changes and significance of the protein expression of N methyl D asparate receptor 1(NMDAR1) in rats after local ischemia reperfusion injury.
白鼠试验表明,如果它们大脑中没有足够的门冬氨酸受体,即使摄入少量酒精,记忆也不会得到改善。
Testing done on rats showed if they did not have enough NMDA receptors, their memory did not improve when given low alcohol doses.
目的:观察新生大鼠缺氧缺血性脑损伤后,海马发育过程中N -甲基- D -天冬氨酸受体的远期表达变化。
AIM: to observe the long-term expression of N-methyl-D-aspartate (NMDA) receptor during the hippocampal development of neonatal rats with hypoxic-ischemic brain damage.
目的:探讨谷氨酸及其N -甲基(酰)- D -门冬氨酸受体(NMDAR1)在大鼠前额叶执行控制功能中的作用机制。
AIM: To study the effect and mechanism of glutamic acid (glu) and NMDAR1 in prefrontal cortex executive control of rats.
目的:观察慢性复合应激对大鼠学习与记忆的影响及应激后脑海马内N-甲基-D-天冬氨酸受体亚基NR2A,NR2B表达的变化。
AIM: To study the effects of chronic multiple stress on learning and memory and changes of N-methyl-D-asparagic acid (NMDA) receptor subunits NR2A and NR2B expression in hippocampus of rats.
与之相反,L -甲硫氨酸增加了甲基化水平,从而减弱了正常老鼠中糖皮质激素受体基因的表达,导致了恐惧、焦虑和对压力的强烈反应。
By contrast, L-methionine increased the level of methylation and thus reduced the expression of the gene in animals with loving mothers, and led to fear, anxiety and a heightened response to stress.
CD 24并不具有胞质内结构域,但通过Siglec - g传递的信号就包括了一个免疫受体酪氨酸相关抑制性基序immune receptor tyrosine - based inhibitorymotif (ITIM)。
CD24 does not contain a cytosolic domain, and signals through Siglec-G, which contains an immune receptor tyrosine-based inhibitory motif (ITIM).
中国的非小细胞肺癌病人中吉非替尼敏感的表皮生长因子受体酪氨酸激酶区域的突变。
Gefitinib-sensitive mutations of the epidermal growth factor receptor tyrosine kinase domain in chinese patients with non-small cell lung cancer.
这种蛋白质中在关键位置上含有苯基丙氨酸,它在与MC1R受体结合时起到很重要的作用。
These proteins have a phenylalanine in a key position that plays an essential role in binding on MC1R receptors.
目的研究大鼠脑局灶性缺血再灌注模型中N甲基D天冬氨酸(NMDA)受体随时间的变化。
Objective To study the changes of N methyl D aspartate(NMDA) receptor in the rat brain during reperfusion after local ischemia.
PDGF受体酪氨酸激酶抑制剂在胰腺癌中是否有作用? ?
Is PDGF tyrosine kinase inhibitor effective in pancreatic cancer?
受体酪氨酸蛋白激酶是细胞信号转导进行的关键信号酶,在生长因子调控细胞生长、发育与功能的过程中起着重要的生理作用。
Receptor tyrosine protein kinase is one of key kinases in cell signal transduction and plays an important role in the process of cell growth, development and functions regulated by growth factors.
目的探讨胰岛素受体酪氨酸激酶(TK)活性变化在胰岛素抵抗(IR)发生中的作用。
Objective to investigate the change of insulin receptor tyrosine kinase (TK) activity in the pathogenesis of insulin resistance (IR).
目的:建立红细胞胰岛素受体酪氨酸蛋白激酶(IRTK)的活性测定法。
Objective: to establish a method of detecting insulin receptor tyrosine kinase (IRTK) activity from erythrocytes.
胍丁胺是左旋精氨酸在左旋精氨酸脱羧酶催化下脱羧基的产物,是咪唑啉受体的内源性配体。
Agmatine formed by the decarboxylation of L-Arginine by the enzyme L-arginine decarboxylase, has been postulated to be an endogenous ligand for imidazoline receptors (I-R).
目的观察瘦素对大鼠肝细胞瘦素受体蛋白、基因表达及酪氨酸磷酸化的影响。
Objective to investigate effects of leptin on gene and protein expression and tyrosine phosphorylation of leptin receptor in rat hepatocytes.
详细介绍了VEGF受体酪氨酸激酶抑制剂的研究进展。
The inhibitor of VEGF receptor tyrosine kinase was introduced in detail.
对丁酸钠转化前后的人红白血病细胞林k- 562的表面胰岛素受体数量、胰岛素受体酪氨酸蛋白激酶活性及细胞内源性底物进行了研究。
In this paper, the quantity of insulin receptors and the receptor tyrosine kinase activity and its endogenous substrates were comparatively studied in K-562 cells before and after transformation.
因谷氨酸代谢异常,过度释放和对突触后受体的高频刺激,引起了兴奋性神经毒性,导致神经元死亡。
The abnormal metabolism and excess release of Glutamic acid as well as high-frequency stimulation to the postsynaptic receptor induce excitatory neural toxicity, resulting in the death of neurons.
目的探讨兴奋性氨基酸受体拮抗剂磷酸甲基谷氨酰氨酸(GAPA)对胆红素神经毒性的影响。
Objective To explore the effect of NMDA receptor antagonist glutamyl amino methyl phosphonic acid (GAPA) on the bilirubin neurotoxicity.
目的谷氨酸NMDA受体拮抗剂地卓西平(MK801)对大鼠急性吗啡依赖戒断性情绪反应的影响。
ObjectiveTo investigate the effect of NMDA receptor antagonist MK801 on the negative affection induced by withdrawal from acute morphine dependence in rats.
产生LTP的生物学基础之一是海马神经元突触上的N -甲基- D -天门冬氨酸(NMDA)受体。
And the N-methyl-D-aspartate (NMDA) receptor on the synaptosome in hippocampus is one of the biological bases of LTP.
目的探索肝硬化时肝组织细胞胰岛素受体(IR)和酪氨酸蛋白激酶(TPK)含量的变化规律。
Objective to investigate the relationship between the expression of insulin receptor (ir) and the content of tyrosine protein kinase (TPK) in patients with hepatic cirrhosis.
新受体可与先前报道的以谷氨酸为靶向的尿基受体和以合成叶酸的喋啶为靶向的受体相比。
The new receptors are compared with previously reported urea-based receptors targeting the glutamic acid residue and receptors targeting the pteridine substructure of folic acid.
酪氨酸激酶型受体、G蛋白偶联受体和离子通道型受体是细胞表面三类主要受体。
Receptor tyrosine kinases (RTK), G protein-coupled receptors (GPCR) and ion channel receptors are main cell surface receptors.
PTK787因其对肿瘤抑制的出色疗效、口服生物利用度高等特点而成为VEGF受体酪氨酸激酶抑制剂中的佼佼者。
PTK787 is the most promising VEGF receptor- tyrosine kinase inhibitor in pipeline because of its potency in tumor inhibition and oral bioavailability.
PTK787因其对肿瘤抑制的出色疗效、口服生物利用度高等特点而成为VEGF受体酪氨酸激酶抑制剂中的佼佼者。
PTK787 is the most promising VEGF receptor- tyrosine kinase inhibitor in pipeline because of its potency in tumor inhibition and oral bioavailability.
应用推荐