这些发现提供了更多证据，表明了在可食用动物身上使用氟喹诺酮类药物会带来哪些问题。
The findings add to the growing body of evidence suggestive of the problems of using fluoroquinolonones in food-producing animals.
目的是探讨外排泵在嗜麦芽窄食单胞菌中对氟喹诺酮类药物的耐药性中的作用。
The objective is to explore the role of efflux pump in drug resistance to fluoroquinolones in Stenotrophomonas maltophilia.
结论应高度重视氟喹诺酮类药物的不良反应。
CONCLUSION Attach the highly importance to ADRs of the fluoroquinolones.
使用抗生素，特别是使用氟喹诺酮类药物，是一个危险因素。
Antibiotic use, especially use of fluoroquinolones, is a risk factor.
CCCP等能量抑制剂可加强细菌对氟喹诺酮类药物的摄取量。
The energy resistance inhibiter, such as CCCP, can intensify bacterial ingestion to fluoroquinolone drugs.
结果：归纳总结出氟喹诺酮类药物的不良反应发生的一般规律和有关特征。
RESULTS: The general rule and characteristics of occurrence of adverse reactions resulted from quinolones have been summarized.
目的：探讨主动外排泵在嗜麦芽寡养单胞菌对氟喹诺酮类药物耐药中的作用。
Objective:To explore the role of efflux pump in drug resistance to fluoroquinolones in Stenotrophomonas maltophilia.
注意：不要以为氟喹诺酮类药物对假单胞菌都有相同的功效，因为这不是事实；
NOTES: do not assume that all fluoroquinolones have equal efficacy against Pseudomonas, because they don't;
结果氟喹诺酮类药物具有不错的市场应用前景，但需注意可能的不良反应及耐药性的发生。
Results the results indicate that fluoroquinolone had perfect market prospect, however, the possible adverse drug reactions and resistance should be paid much attention.
第三代喹诺酮类药物，即氟喹诺酮类药物，具有抗菌谱广、抗菌作用强、作用迅速、副作用少等优点。
F-quinolones, as the third generation of quinolones, have many advantages such as broad antimicrobial spectrum, strong and fast antimicrobial effects and a few side-effects.
本文简要回顾了部分氟喹酮类药物的PK/PD研究，并对莫西沙星等主要氟喹诺酮类药物PK/PD参数进行总结。
In this article, we review PK/PD investigation of fluoroquinolones, and give a summary of PK/PD parameter of moxifloxacin and some other fluoroquinolones.
目的：研究不同药物浓度、不同化学结构的氟喹诺酮类药物对突变选择窗(MSW)内筛选的大肠埃希菌耐药突变体的靶位耐药基因的影响。
OBJECTIVE To investigate the effect of drug concentration, drug structure of fluoroquinolones on the resistant gene of Escherichia coli mutants selected in the mutant selection window (MSW).
目的：研究不同药物浓度、不同化学结构的氟喹诺酮类药物对突变选择窗(MSW)内筛选的大肠埃希菌耐药突变体的靶位耐药基因的影响。
OBJECTIVE To investigate the effect of drug concentration, drug structure of fluoroquinolones on the resistant gene of Escherichia coli mutants selected in the mutant selection window (MSW).
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