介绍了计算机模拟蛋白质折叠问题的背景、模型和意义。
We mainly introduce the background, model and importance of computer simulation for protein folding.
分子动力学模拟：模拟蛋白质在折叠时的旋转一直是一种组合上的噩梦。
Molecular Dynamics Simulations : Simulating the gyrations that proteins make as they fold has been a combinatorial nightmare.
这是因为模拟蛋白质折叠时所进行的计算，其类型能被图形处理器很好的适应。
That is because GPUs are well suited to the types of calculations involved when simulating protein folding.
介绍了用分子动力学模拟与热力学积分法相结合 ，模拟蛋白质与配体的绝对结合自由能的方法 。
Molecular dynamics simulation and thermodynamic integration method were used to calculate the absolute binding free energy of the protein- ligand complex.
在模拟蛋白质折叠的遗传算法基础上，采用晶格模型，设计了一个用于蛋白质折叠模拟的软件系统，并举例说明该系统的用法。
On the basis of genetic algorithms for protein folding, a software system of protein folding simulation with lattice model is designed.
斯科尔斯和他的研究小组利用激光脉冲模拟太阳光的吸收，研究了海藻的聚光蛋白复合物。
Scholes and his team studied the light-harvesting protein complexes within algae by using laser pulses to mimic absorption of sunlight.
科学家试图理解蛋白质折叠的一种方式是通过在计算机上进行模拟。
One way scientists try to understand protein folding is by simulating it on computers.
通过模拟有助人体、自然存在的金属元素，诸如钙、铁、锌，并结合相同的分子与蛋白质，铅会导致大脑损伤。
Lead causes brain damage by mimicking helpful metals found naturally in the body, such as calcium, iron and zinc, and binding with the same molecules and proteins.
过去他一直在比对人和病毒的基因，看病毒是否能演化模拟出人的蛋白质。
He had been comparing the virus genes with human genes to see if the virus might have evolved to mimic our own proteins.
经过实验技术和计算机模拟，他们展现了这种蛋白的确切结构。
The research team present a definitive structure of the protein, which was obtained using experimental techniques and computer simulation.
一种新的研究揭示了，有一种新的药物治疗——模拟抗氧化剂的抑制作用——促进蛋白——能够杀死胰腺癌细胞。
A novel drug therapy - that mimics the suppression of an antioxidant-promoting protein - kills pancreatic cancer cells, new research reveals.
研究人员已经发明了精敏的新技术，来模拟化学药品，在紧密结合的沉默基因表达的DNA -蛋白复合体上做标记。
Researchers have devised clever new techniques to mimic the chemical marks on tightly wound DNA-protein complexes that silence gene expression.
这种分子模拟，意即当免疫系统对口腔感染有反应时，它也同时攻击了机体的蛋白质，因此导致了动脉疾病的发生。
This molecular mimicry means that when the immune system reacts to oral infection, it also attacks host proteins, causing arterial disease.
用从苹果中提取的蛋白和果胶，加入绿原酸和儿茶素， 组成模拟体系；
Simulated system was made by adding chlorogenic acid and catechin to both protein and pectin extracted from apple.
目的：观察模拟失重条件下由骨形态发生蛋白2诱导的ROS17/2.8细胞中MEK1激酶活性的变化。
OBJECTIVE: To investigate the effects of simulated weightlessness on the activity of MEK1 induced by BMP-2 in ROS17/2.8 cells.
蛋白质结构构象呈现明显的规律，研究其在特定构象空间的分布对蛋白质结构预测和模拟具有重要意义。
Research on conformational space of protein structure in which proteins take clear regulation plays a key role in protein structure prediction and simulation.
模拟结果显示：模型蛋白分子的某些折叠中间态会陷入局部能量最低状态而无法完成折叠；
The thermodynamic feasible status of the model protein, as described by HP model, and its folding intermediates were captured.
结论筛选的该噬菌体克隆展示肽可模拟JEVE蛋白的部分抗原性。
Conclusion This peptide displayed on positive phage may mimic partial antigenicity of JEV E protein.
由于其独特的结构和性能，近年来在蛋白质结构模拟、分子链构象研究、生物医学等领域被广泛地加以研究。
Due to their unique structures and properties, synthetic polypeptides recently have been studied widely in the field of protein simulation, macromolecular conformational study and biomedicine.
根据超分子化学基本原理，利用谱学方法和显微技术，以胶原蛋白、多糖等生物大分子为超分子模板，建立体外模拟体系。
Based on the primary principles of supramolecular chemistry, biomacromolecules such as polysaccharides or proteins are used as supramolecular template to found simulation systems in vitro.
综述了植物蛋白，特别是大豆蛋白制作模拟干酪的研究进展。
Research advance in cheese analogs processing from plant proteins, especially soybean protein, was reviewed in this paper.
简要地介绍了模拟退火算法，遗传算法，人工神经网络和图论算法在蛋白质结构预测中的应用。
The paper briefly introduces some modern optimum algorithms of simulated annealing, genetic algorithms, neural networks and graphic algorithms in and applied in prediction of protein structure.
结论模拟失重可诱导PC 12细胞NO的合成，增加蛋白质氧化损伤程度。
Conclusions Simulated weightlessness may induce the (over) production of NO, and resulted in increased protein oxidative damage in PC12 cells.
利用脂肪氧合酶、亚油酸和大豆分离蛋白构建的模拟体系，研究了脂质氧化诱导的大豆蛋白质聚集的机理。
A model system consisting of linoleic acid, lipoxygenase and soybean protein isolate was established to investigate the mechanism of aggregation of soybean proteins induced by lipid oxidation.
首先采用点电荷模拟，形成离子交换剂内孔配基模拟表面，构筑蛋白质-介质配基模拟表面体系。
Firstly, based on the analysis of pore radius and ligand distribution, the net of charged points were used to construct a simulated system of protein - adsorbent porous surface of ion exchangers.
通过在位于顾客蛋白结合区该位点制造突变，可模拟乙酰化或者去乙酰化氨基酸。
Mutations were made at this site, which is located in a region where client proteins bind, to mimic either an acetylated or a non-acetylated amino acid.
这一模拟系统可以预测荧光蛋白表达是如何因启动子化学抑制剂水平不同而发生变化的。
The simulation was able to predict how fluorescent protein expression varied with levels of promoter-inhibiting chemicals.
这一模拟系统可以预测荧光蛋白表达是如何因启动子化学抑制剂水平不同而发生变化的。
The simulation was able to predict how fluorescent protein expression varied with levels of promoter-inhibiting chemicals.
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