核苷类似物是一类重要的抗病毒和抗癌药物。
Nucleoside analogs are important candidates in the searching of antiviral and anticancer drugs.
该方法适用于从酶反应混合物中分离核苷类似物。
The method was suitable for separating nucleoside analogues from enzyme reaction mixture.
核苷类似物单一疗法是目前对很多患者的标准治疗。
Nucleoside analog monotherapy is the current standard of care for many patients.
治疗时必需面对的第二个棘手的问题是是否使用干扰素或核苷类似物。
When treatment is deemed necessary the second difficult issue is whether to use interferon or analogues.
合成了系列糖苷的双杂环化合物及含有糖结构的核苷类似物，培养单晶。
Series of glycosides have been designed and synthesized, and some of the sing crystals have been prepared.
结果表明，含磷腺嘌呤核苷类似物对乳腺癌细胞增殖具有显著的抑制作用。
The results show that phosphorus adenine nucleotide analogues have significantly inhibited effects on proliferation of the breast cancer cell.
1998年首个核苷类似物药物拉米夫定推出之前，慢性乙肝病毒感染者可选的有效治疗途径一直都非常有限。
Effective treatment options for individuals with chronic hepatitis B infection were limited until 1998 when lamivudine, the first nucleoside analogue drug, was introduced.
核苷类似物联合人工肝治疗可加快肝功能好转，缩短病程，降低病死率，降低血清HBVDNA水平。
Treating with nucleosides plus ALSS could accelerate the amelioration of liver function, shorten course of disease, decrease mortality and HBV DNA level.
作为天然核苷受体的竞争性抑制剂，糖环部分化学改造的核苷类似物在过去的几十年中得到了深入的研究。
As competitive inhibitors of natural nucleoside receptors, sugar-modified nucleoside analogues have been well studied in the past few decades.
胸腺肽及核苷酸类似物如拉米呋定、法昔洛韦等。
Conclusion: interferon, thymosin and new nucleotide similitude are efficacious medicines.
氨基核苷嘌呤霉素是合成嘌呤毒素的半合成类似物中关键性的中间体。
Puromycin aminonucleoside is the key intermediate in the synthesis of semi-synthetic analogues of puromycin.
本文总结了近十几年来立体控制性合成含手性磷酸酯基的寡核苷酸类似物的进展，重点介绍了寡核苷酸硫代磷酸酯和甲基膦酸酯的立体控制性合成方法。
In this review, the progress of stereocontrolled synthesis of P-chiral analogues of oligonucleotides was summarized with the emphasis on oligonucleotide phosphorothioates and methylphosphonates.
核苷(酸)类似物药物可以有效抑制HBV的复制，目前已成为治疗HBV感染的首选药物。
Nucleos (t) -ide analogs are able to inhibit the replication of HBV efficiently. They have become the primary choice in the treatment of chronic HBV infection.
对于已经感染的患者我们给予多种核苷(酸)类似物治疗。
For patients already infected we can now treat these patients with a variety of NUCs.
嘧啶类似物bromodeoxyuridine (BrdU)之类的卤化核苷酸能够用于标记活细胞和组织中的新生dna。
Halogenated nucleotides such as the pyrimidine analog bromodeoxyuridine (BrdU) are useful for labeling nascent DNA in living cells and tissues.
卤代核苷酸如嘧啶类似物溴脱氧尿苷(BrdU)对于新生活细胞和组织中的DNA进行标记是有用的。
Halogenated nucleotides such as the pyrimidine analog bromodeoxyuridine (BrdU) are useful for labeling nascent DNA in living cells and tissues.
卤代核苷酸如嘧啶类似物溴脱氧尿苷(BrdU)对活细胞和组织中的DNA进行标记是有用的。
Halogenated nucleotides such as the pyrimidine analog bromodeoxyuridine (BrdU) are useful for labeling nascent DNA in living cells and tissues.
卤代核苷酸如嘧啶类似物溴脱氧尿苷(BrdU)对活细胞和组织中的DNA进行标记是有用的。
Halogenated nucleotides such as the pyrimidine analog bromodeoxyuridine (BrdU) are useful for labeling nascent DNA in living cells and tissues.
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