携带基因的DNA线型分子构成染色体,染色体端粒位于染色体末端。
The thread-like DNA molecules that carry genes are packed into chromosomes, the telomeres being the caps on their ends.
承载着各种基因的DNA分子就象一根长长的细线,并依一定规则扭曲成染色体,而端粒就象一顶帽子那样覆盖在染色体末端。
The long, threadlike DNA molecules that carry our genes are packed into chromosomes, the telomeres being the caps on their ends.
端粒可以保护基因,这种情况恰恰像鞋带末端的塑料帽。
Telomeres protect the genes, much like the plastic tips on the ends of shoelaces.
目的:克隆并表达艰难梭菌毒素A羧基末端受体结合区基因。
AIM: to obtain the high expression of the gene coding for clostridium difficile toxin a receptor binding zone.
目前已鉴定的这一基因家族的多数成员均参与几种重要的DNA修复途径,包括碱基切除修复、同源重组修复和非同源末端重接。
Most members of the XRCC genes family participated in several DNA repair pathways, including base excision repair, homologous recombination repair and non-homologous end joining.
目的探讨泛素羧基末端水解酶l1 (uch - L1)基因的S18Y多态性在散发性阿尔茨海默病(AD)发病机制中的作用。
Objectives: To explore the role of S18Y polymorphism of Ubiquitin Carboxy-terminal Hydrolase-L1 (UCH-L1) gene in the pathogenesis of sporadic Alzhermer's disease (AD).
方法:用基因测序、氨基酸组成分析、N末端氨基酸测序、胰肽图谱、IEF、分子量、紫外扫描等各种实验手段对重组L 天冬酰胺酶及其天然品进行了全面比较。
Methods:Various analytical techniques including gene sequencing, amino acid composition, analysis of N terminal amino acid analysis, peptide mapping, IEF, molecular weight and UV scanning were used.
为了解人类LDL受体基因内含子15的遗传背景,利用长链PCR和锚定PCR分离了LDL受体基因外显子15-内含子15-外显子16和内含于15的3’末端片段。
To understand intron 15 of human LDL receptor gene, the DNA fragments from exon 15 to exon 16 and the 3' end of intron 15 were amplified with long chain PCR and anchored PCR.
方法:本课题前期阶段已将含谷氨酰胺酶基因C末端反义序列的质粒转染入胃癌细胞并命名为SGC-7901~(GA)。
Methods: The gastric carcinoma cells had been successfully transfected with plasmid containing the C' distal end antisense sequence of glutaminase gene and called SGC-7901GA in previous researches.
染色体末端的端粒对于细胞基因组的遗传稳定性至关重要。
The ends of chromosomes, the telomers, are important for the genetic stability of our cells.
结论:本文的研究结果提示X染色体长臂末端可能是卵巢早衰的特异性基因区段并与X染色体末端端粒的缺失有关。
Conclusion: The result showed that terminal deletion of Xq and telomeric deletion of X chromosome were important factors of premature ovarian failure.
用双脱氧链末端终止法测序结果表明,NS 1基因扩增片段5端的部分碱基序列并未发生改变。
The result of the nucleotide sequence determined by dideoxy chain-termination method indicated that 5 '-terminal nucleotide sequence of the amplified NS1 fragment was not changed.
目的:通过使用3末端碱基游移混合引物,减少引物末端错配,提高多变区基因片段的PCR检测阳性率。
Objective: To reduce the risk of 3 -terminal mismatch between primers and template and increase the sensitivity of polymerase chain reaction (PCR) in the detection of variable region of DNA.
“组蛋白密码”是由起调控基因转录功能的组蛋白末端的共价修饰所组成。
The "histone code" is comprised of the covalent modifications of histone tails that function to regulate gene transcription.
就像是在我们鞋带最末端的那一小块塑料一样。端粒可以帮助保护基因免于磨损或者是破裂。
Like the plastic tips on the ends of shoelaces, telomeres help to protect genes against wear and tear.
其中碳末端45 0个核苷酸的序列测定和分析提示,该7株病毒为麻疹野病毒H1基因型。
Sequence analysis of 450bp of C-terminus of the N gene indicated that all of the 7 isolates were H1 genotype.
端粒酶的活化可延长染色体的末端dna,维护基因组的稳定。
Activation of telomerase can elongate telomere length and maintain gene stability.
用双脱氧链末端终止法测序结果表明,NS1基因扩增片段5’端的部分碱基序列并未发生改变。
The result of the nucleotide sequence determined by dideoxy chain-termination method indicated that 5'-terminal nucleotide sequence of the amplified NS1 fragment was not …
用双脱氧链末端终止法测序结果表明,NS1基因扩增片段5’端的部分碱基序列并未发生改变。
The result of the nucleotide sequence determined by dideoxy chain-termination method indicated that 5'-terminal nucleotide sequence of the amplified NS1 fragment was not …
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