• 美国食品药品管理局批准治疗转移克隆的贝单抗,血管内皮生长因子单克隆抗体

    Bevacizumab, a monoclonal antibody targeting vascular endothelial growth factor, is approved by the US Food and Drug Administration for metastatic colon cancer.

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  • 目的:众多血管再生性因子中,血管内皮生长因子及其受体2公认促使血管生成关键性因素

    OBJECTIVE Vascular endothelial growth factor VEGF and its receptor 2 are the generally accepted key factor on the formation of blood vessel in numerous blood vessel regeneration factors.

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  • 采用化学治疗药物(贝伐单抗中和血管内皮生长因子人源化抗体)治疗导致蛋白尿肾功能损害

    Treatment with the chemotherapeutic agent bevacizumab, a humanized mab that neutralizes vascular endothelial growth factor, can lead to proteinuria and renal damage.

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  • 然而众多血管生成因子中,血管内皮细胞生长因子(VEGF)有力血管生成因子

    But in many vascular growth factors, vascular endothelial cell growth factor (VEGF) is the most important vascular growth factor.

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  • 目的血管内皮生长因子(VEGF)血管渗透因子一种重要血管生成因子主要血管内皮细胞产生

    Objective: vascular endothelial growth factor (VEGF) also is named vascular permeability factor, which is one of the important angiogenesis factors and mainly produced by vascular endothelial cells.

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  • 血管内皮生长因子(VEGF)目前发现强有力的血管形成因子

    Vascular endothelial growth factor (VEGF) has been found to be the most powerful angiogenic factor.

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  • 结论骨髓间质干细胞大鼠心脏可以转化血管内皮细胞分泌血管内皮生长因子治疗缺血性血管疾病理想细胞来源

    CONCLUSION: MSCs can be transformed into vascular endothelial cells or secrete VEGF in rat hearts, thus is the ideal cell source of therapy in ischemic cardiovascular disease.

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  • 新生血管大量形成实体生长转移中起关键作用血管内皮生长因子(VEGF)介导肿瘤血管生成的主要因素

    New vessel formation plays a key role in tumor growth and transforming, and the Vascular endothelial growth factor (VEGF) is the most important factor inducing tumor vessel formation.

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  • 第1模型通过注射了血管内皮生长因子抗体或者可溶性血管内皮生长因子受体1,从而获得的。

    The first model is generated by injection of antibodies to vascular endothelial growth factor or soluble vascular endothelial growth factor receptor 1.

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  • 血管内皮生长因子促进血管生成的重要调节因子

    Vascular endothelial growth factor VEGF plays a central role in tumor angiogenesis.

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  • 结论缺氧可以上调小鼠组织中的血管内皮生长因子引起血管新生,可能可逆的。

    CONCLUSION: Hypoxia can up-regulate the expression of VEGF in the lung tissue of mice and plays an important role in angiogenesis, and the change might be reversible.

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  • 血管内皮生长因子VEGF一类能促进血管生成的细胞因子能诱导细胞的有丝分裂调节内皮细胞通透性。

    The vascular endothelial growth factor (VEGF) is a kind of potent angiogenic cytokine that induces mitosis and regulates the permeability of endothelial cells.

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  • 血管内皮生长因子促进血管生成的重要调节因子

    Vascular endothelial growth factor (VEGF) plays a central role in tumor angiogenesis.

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  • 此外似乎一种表达时间当然分析重要虽然没有定量EGFP血管内皮生长因子

    Also, it seems that a time course of expression was important in the analysis although no quantitation was provided for the EGFP or the VEGF.

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  • 血管内皮生长因子色素上皮细胞衍生因子目前发现作用最强角膜新生血管形成促进因子抑制因子

    Vascular endothelial growth factor and pigment epithelium-derived factor are most enhancing factor and strongest inhibitory factor of corneal neovascularization(CNV)at present.

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  • 血管内皮生长因子(VEGF)可能涉及主要因素之一可能唯一个。

    Vascular endothelial growth factor (VEGF) is probably one of the main factors involved but perhaps not the only one.

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  • 血管内皮生长因子重要血管生成因子调节内皮增殖血管生成、调节血管通透性及血栓形成

    VEGF is an important angiogenesis factor, which can regulate endothelial proliferation, angiogenesis, permeability of blood vessel, thrombogenesis.

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  • 血管内皮生长因子多功能的细胞因子参与机体多种生理病理过程

    Vascular endothelial growth factor (VEGF) is a multi-effective cytokine, which participates many physiological and pathological processes.

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  • 血管内皮生长因子(VEGF)目前所知作用最强的促血管生成因子之一,可以直接间接地参与血管生成的每个环节

    Vascular endothelial growth factor (VEGF) is one of the most powerful pro-angiogenesis factor at present, which can participate in each link of the angiogenesis directly or indirectly.

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  • 目的肿瘤血管生成肿瘤生长侵袭基础血管内皮细胞生长因子VEGF重要的血管生成因子许多人类肿瘤均可检测到了这种因子

    Objective: Angiogenesis of tumor is the base of tumor growth and invasion. Vascular endothelial growth factor (VEGF) is the most potent angiogenesis factor and has been detected in many human tumours.

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  • 血管内皮生长因子目前所知唯一作用血管内皮生长因子血管发生中处枢纽地位。

    Vascular endothelial growth factor is only one endothelium specific growth factor that plays a pivotal role in angiogenesis.

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  • 血管内皮生长因子- A (VEGF - A)最近认为中枢神经系统中一重要的神经护卫

    Vascular endothelial growth factor-A (VEGF-A) has recently been recognized as an important neuroprotectant in the central nervous system.

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  • 贝伐单抗阻断血管内皮生长因子(VEGF)受体活性肿瘤血管生成,增殖转移重要因子

    Bevacizumab blocks the action of the vascular endothelial growth factor (VEGF) receptor, a key factor in tumor angiogenesis, growth, and metastasis.

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  • 使用特定药理学制剂抗氧化剂PKC抑制剂靶向血管内皮生长因子表达可能证明治疗糖尿病性视网膜病变有效

    Targeting VEGF expression with specific pharmacological agents, such as antioxidants and PKC inhibitors, may prove efficacious for the treatment of diabetic retinopathy.

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  • 目的血管内皮生长因子CVEGF-C)属于血管内皮生长因子VEGF家族成员认为目前发现唯一特异性淋巴管生成因子

    Objective:Vascular endothelial growth factor C(VEGF-C) recently has been identified as a new member of the VEGF family and is considered as the single specific lymphangiogenic factor.

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  • 目的血管内皮生长因子CVEGF-C)属于血管内皮生长因子VEGF家族成员认为目前发现唯一特异性淋巴管生成因子

    Objective:Vascular endothelial growth factor C(VEGF-C) recently has been identified as a new member of the VEGF family and is considered as the single specific lymphangiogenic factor.

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