PPAR激动剂，是细胞核激素受体家族转录因子的一个成员，被广泛用来治疗II型糖尿病，而且相对无毒。
Agonists of PPAR, a member of the nuclear hormone receptor family of transcription factors, are widely used in the treatment of type II diabetes and are relatively non-toxic.
结论：褪黑色素可通过作用于外侧缰核的阿片受体而影响其痛相关神经元对痛刺激的反应，这可能是褪黑色素中枢镇痛机制之一。
Conclusion: Melatonin can change the responses of pain neurons to pain stimulation via opioid receptor in the LHb, which might be one of analgesic mechanisms by MEL.
背景肝x受体是一种核受体，与细胞内胆固醇及糖等能量代谢有关。
Background Liver X receptors (LXRs) are members of the nuclear hormone receptor superfamily which involve in energy metabolism of intracellular cholesterol and glucose regulation.
核受体家族的经典作用机制是在其配基存在下结合在靶基因的应答元件上，从而在转录水平上调节基因的表达。
The classical mechanism for nuclear receptors to regulate gene expression is to bind the hormone response element(HRE) on the target gene in the presence of their ligands.
我们惊奇地发现，在肺癌和正常肺脏组织中核激素受体的表达谱模式对肺癌患者预后判断是如此之精确。
We were amazed to find that the pattern of expression of nuclear receptors in both lung cancers and normal lung tissue were so predictive of a patient's outcome.
属于核受体超家族成员，是一个孤儿受体。
GCNF (Germ Cell nuclear Factor) is a member of nuclear receptor superfamily and also an orphan receptor.
供体核和受体胞质是影响核移植重构胚重编程的主要因素。
The donor cell and recipient cytoplasm are main factors in the nuclear transfer reprogramming.
HR蛋白是细胞核受体辅阻遏物的发现证明HR蛋白是通过在毛发周期中调节基因表达来发挥作用的。
The discovery that the HR protein is a nuclear receptor corepressor indicated that HR function in hair cycling is by regulating gene expression.
核受体是配体活化的转录因子，能调控大量的靶基因。
Nuclear receptors (NRs) are ligand-activated transcription factors that regulate the activation of a variety of important target genes.
由于核受体在调节脂质代谢、糖代谢以及炎症反应方面发挥重要作用，它们是治疗心血管疾病理想的靶标。
As NRs play major roles in the regulation of lipid metabolism, glucose homeostasis, and inflammatory processes, they are considered as ideal targets for the treatment of cardiovascular diseases.
法尼酯x受体(FXR)是代谢性核受体超家族中的一员，在调节胆汁及脂类等物质代谢、维持内环境的稳定方面发挥着重要作用。
Farnesoid X receptor (FXR), a member of the metabolic nuclear receptor superfamily, plays key roles in maintaining bile acid and lipid homeostasis.
法尼酯x受体(FXR)是代谢性核受体超家族中的一员，在调节胆汁及脂类等物质代谢、维持内环境的稳定方面发挥着重要作用。
Farnesoid X receptor (FXR), a member of the metabolic nuclear receptor superfamily, plays key roles in maintaining bile acid and lipid homeostasis.
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