忧郁发作的时候，又会情绪低落、无助无望，甚至觉得活著没有价值和意义，甚或自杀。
During the Major Depressive Episode, patients feel so depressed, helpless, and hopeless that they consider life is worthless or meaningless. These feelings may even lead to suicide.
这让他看起来不是天真、过度值得信赖，就是脆弱、无望的无助。
This makes him appear either naive and too trusting, or vulnerable and hopelessly helpless.
如果你感到抑郁，你可能感到筋疲力尽、无助、无望。
If you have depression, you may feel exhausted, helpless, and hopeless.
如果你感到抑郁，你可能感到筋疲力尽、无助、无望。
If you have depression, you may feel exhausted, helpless and hopeless.
感觉无望、无助、无价值。
你让我觉得无助又无望。
抑郁能使你感到精疲力竭、没有价值、无助和无望。
Depression can make you feel exhausted, worthless, helpless, and hopeless.
我们理解生活的艰辛无助和长久以来对于未来的无望将使人产生道德的无力感。
Guo's integrity, as we understood that being in desperate needs for so long and feeling helpless and hopeless on a daily basis would surely yield a sense of powerlessness inside the person.
两人对曾经由恨到爱的过去感到无奈、无助、无望，在乘机之前两人在一家咖啡厅喝咖啡。
Two people to ever from hate to the in the past feel of the love helpless, help, hopeless, two people drank coffee in a coffee parlor before seize an opportunity.
该人感到无助，无望和无价值的。
该人感到无助，无望和无价值的。
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