科研院所在中药新药研发中的作用不突出。
The research institutes hadn't played a prominent role in the research of new drug.
旨在为CHS的预防与治疗及新药研发提供思路。
The goal is to supply the ideas concerning the prevention and treatment of CHS, and drug discovery.
目的：探讨新药研发及其与全球化需求之间的关系。
OBJECTIVE: To discuss on the relationship between the research and development of new drugs and the global demands.
结论提出了改善新药研发项目成本管理的几点对策。
Conclusion some countermeasures improving of cost management are proposed.
结果：根据模型的评价结果，可以对新药研发项目进行优选排序。
RESULTS:The new drug research&development projects can be optimized and ranked based on the evaluation results on the model.
方法对华北制药集团与军事医学科学院新药研发人员进行问卷调查。
Methods Questionnaire study was administrated on the researchers of Academy of Military Medical Science and the North China Pharmaceutical Group Corporation.
着重对新药研发、申报、审批环节造假行为法律制裁体系进行了考察。
They focus on the legal sanctions system against ACTS of forgery occurred during the process of the new drug research and development, declaration, and approval.
新药研发具有费用高、周期长和风险大的特点，尤其是在新药临床研究阶段。
Drug development is characterized by high costs, long cycle and big risk, especially in clinical trial.
目的：强调中药新药研发的目的是推出有实实在在疗效的、可以解决临床难题的新药。
Object: it must be emphasized that the aim of study and development of new drug of the traditional clinical disease.
本文主要从新药研发和临床治疗药物监测这两个方面综述了定量药理学国内外研究进展。
This paper reviewed the advances of pharmacometrics employed in new drug research and development and therapeutic drug monitoring both at home and abroad.
该平台由GRP实验管理系统、GLP新药申报系统和新药研发标准化流程管理系统组成。
This platform is composed by GRP experiment management system, GLP new drug application system and drug discovery standard workflow management system.
研究发现大脑内（与阿尔兹海默症相关的）小块蛋白质凝结干扰记忆功能，可能成为新药研发的好目标；
Findings that small clumps of a protein in the brain (already linked with Alzheimer's) interfere with memory, and so may be a good target for new drugs;
虚拟筛选过程将产生大量复杂的中间数据，对这些数据的有效管理是下阶段新药研发的基础。
A large amount of complex data will be produced in virtual screening and the effective management of these data is the basis of next research in drug discovery.
方法采用文献查阅法和网上信息搜集法等方法，分析了新药研发项目成本管理中遇到的一些问题。
Methods to analyze some problems in cost management for new drug research and development by looking up some information in related magazines and on line.
新药研发中的出现的新治疗手段也少之又少，制药商转而把钱花在寻找能够治疗多种疾病的特殊生物药品上。
With few new treatments emerging from the drugdevelopment pipeline, drugmakers are pouring money intofinding new uses for specialized biotech drugs that may beeffective against multiple diseases.
设计了利用因特网上多个集群的空闲资源来处理生物医学领域数据密集型计算的新药研发网格(DDG)。
Utilizing the idle resources donated by the clusters that scatter over the Internet, drug discovery grid (DDG) can implement efficient data-intensive biologic applications.
目前设有四个研发板块：新药研发生物部，新药研发技术部，微生物蛋白质工程研究部及中试中国研究部。
Currently, NNRCC has four research functions: Discovery Biology, Discovery Technology, E. coli Research, and CMC Mini-pilot.
但是，如果把加拿大的定价标准搬到美国的话，医药产业的利润率就会下降，而新药研发的进程也势必会减慢。
Nevertheless, if Canada-level pricing came to the United States, the industry's profit margins would drop and the pace of new-drug development would slow.
本文主要综述胚胎干细胞、骨髓间充质干细胞、多能性诱导干细胞的定向分化在新药研发中的作用及研究进展。
This paper reviewed the progress of new drug research of the directed differentiation of embryonic stem cells, bone marrow mesenchymal stem cells and induced pluripotent cells.
美国FDA颁布了《植物药指导原则》以辅助申请者开发植物药，这对中草药新药研发也有极其重要的借鉴意义。
Botanical drug Products promulgated by the us FDA could guide industry sponsors to develop herbal drugs, which was also an important reference for investigating Chinese herbal medicines.
以临床药理模型为基础的新药研发及评估， 孙鹤博士，旅美中国药学家学会，美国食品和药物管理局专家审批官。
Pharmacometrics Model Based New Drug Development and Evaluation, He Sun, Ph. D. , Food and Drug Administration, Association of Chinese-American Pharmaceutical Scientists, MD, USA.
虚拟筛选节省了大部分化合物合成或购买以及实际生物测试的时间和花费，大大加快了新药研发的过程并降低了成本。
Virtual screening has not only speed the process of new drug research and development, but also reduces products costs gristly.
公司开发了包括400多个专利产品的全面的产品组合，为表观遗传学方面的研究和新药研发提供全面系统的解决方案。
The company has developed a comprehensive portfolio of more than 400 proprietary products to provide complete and systematic solutions for epigenetics-related research and drug discovery.
由于新药研发的高投入、高技术、高风险、周期长和过程复杂等原因，使新药的价值形成具有高成本和高附加值的特点。
The characteristics of new drugs are of high cost and high accession, due to high-investment, advanced-technology, high-risk, long-cycle and complicated process of research and development.
近年来定量药理学中涉及的模型化和仿真预测在新药研发、治疗药物监测和临床个体化用药等方面得到了广泛的重视和研究。
Pharmacometrics has been widely valued for its utility of modeling and simulation in drug research and development, therapeutic drug monitoring and individualized therapy.
投资者向医药巨头们传达了一个明确信息：不要再投入巨资用于新药研发，即便公司正在失去旧有药品的专利保护，面临所谓的专利悬崖困境。
Investors had sent Big Pharma a very clear message: Stop spending so much money to create new drugs, even if you're losing exclusivity on your older drugs through the so-called patent cliff.
针对全身性红班性狼疮的有效生物标记扮演支持全身性红班性狼疮治疗药开发企业的重要角色，是促进该市场新药研发速度的主要因素。
The identification of valid biomarkers for systemic lupus erythematosus (SLE) will be an important aid to companies developing drugs for SLE and may speed drug development in this market.
结果与结论：我国应制订药物经济学评价指南并应用于药品定价、报销目录遴选、临床合理用药、疾病防治策略以及新药研发等卫生决策领域。
RESULTS &CONCLUSION:It's necessary for China to formulate pharmacoeconomic guidelines and use it in drug pricing, drug reimbursement, clinical guidance, diseases prevention and new drug R&D.
结果与结论：我国应制订药物经济学评价指南并应用于药品定价、报销目录遴选、临床合理用药、疾病防治策略以及新药研发等卫生决策领域。
RESULTS &CONCLUSION:It's necessary for China to formulate pharmacoeconomic guidelines and use it in drug pricing, drug reimbursement, clinical guidance, diseases prevention and new drug R&D.
应用推荐