观察两组患者用药前及用药后1、2和5 d的血压心率变化，以及多巴胺撤药时间和多巴胺依赖情况。
Changes of blood pressure and heart rate were observed before treatment and on 1, 2 and 5 days after treatment. Dopamine withdrawal time and dependence were viewed.
撤药反应的出现可能与药物对中枢神经系统中血清素、多巴胺、去甲肾上腺素、GABA、胆碱能类递质系统的影响有关。
Appearance of withdrawal reactions may associated with pharmacological effects on serotonin, dopamine, norepinephrine, GABA and cholinergic transmitter in central nervous system.
拆方研究包括单味药研究法、药对研究法、药物组间关系研究法、撤药研究法、正交设计法、聚类分析法、均匀设计法、析因分析法等方法。
The latter includes study of single ingredient, study of functional ingredient group, orthogonal design, clustering analysis, homogeneous design, factorial analysis and so on.
根据Servier提供的信息，此药物在2005年在意大利和西班牙撤市，原因是该药的商业业绩不佳。“他们为什么不在法国也早一点这样做呢？”
The drug was pulled from Italy and Spain in 2005, according to Servier, because it was not commercially successful enough.
根据Servier提供的信息，此药物在2005年在意大利和西班牙撤市，原因是该药的商业业绩不佳。“他们为什么不在法国也早一点这样做呢？”
The drug was pulled from Italy and Spain in 2005, according to Servier, because it was not commercially successful enough.
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