动态拆分技术是将拆分反应与现场消旋化反应相结合的技术。
Dynamic resolution technology combines the resolution with racemization in situ.
外消旋体的动力学拆分反应是制备手性化合物的重要方法之一。
The kinetic resolution of raceme is one of the important ways in the synthesis of chiral compounds.
用菌体细胞对DL -丙氨酸拆分反应中，D -丙氨酸得率平均达87.1%。
The D-Ala recovery rate was 87.1% on the average in the resolution of DL-Ala.
本文讨论了路易斯酸及路易斯碱催化体系在外消旋体(动态)动力学拆分反应中应用的最新进展。
Recent progress in the applications of non-enzymatic system about Lewis acid and base to (dynamic) kinetic resolution reactions of racemes is reviewed.
在近似无限浴的条件下，通过测量间歇拆分反应产生的L -丙氨酸的浓度变化规律，判断反应过程中的速率控制步骤。
In the batch reaction with high ratio of substrate to catalysts, the rate? Controlling step was determined by measuring the concentration variation of produced L-alanine in solution.
筛选以2-溴代丁酸为起始原料，经氨解，酯化，酯胺解，拆分，环合五步反应制得左乙拉西坦。
Screening for 2 - bromo-butyric acid as the starting material, after ammonolysis, esterification, ester amine solution, split, five-step cyclization reaction Levetiracetam.
此外，还对酶膜生物反应器，尤其是其在对外消旋混合物手性拆分以及污水处理方面的应用作了简要的介绍。
In addition, the applications of enzyme-membrane bioreactors, especially in the resolution of racemic mixtures and the treatment of wastewater, have also been briefly discussed.
筛选以2-溴代丁酸为起始原料，经氨解，酯化，酯胺解，拆分，环合五步反应制得左乙拉西坦。
Screening for 2 - bromo- butyric acid as the starting material, after ammonolysis, esterification, ester amine solution, split, five-step cyclization reaction Levetiracetam.
描述了在批式反应器和连续流搅拌反应器(CSTR)中酶动力学拆分对映异构体的不同之处。
The difference between a continuous stirred tank reactor (CSTR) and a batch reactor was analyzed for the enzymatic kinetic resolution of enantiomers.
用正交实验方法筛选出有机相中酶促拆分环氧丙醇反应的最适酶源为猪胰脂肪酶（PPL ） 。
The optimal enzyme resource, porcine pancreatic lipase(PPL), was confirmed by proper test in the resolution of racemic glycidol via esterification with a fatty acid in organic media.
有机相中应用酯化反应，酶法催化拆分消旋醇是获得光学活性醇的重要途径。
The main route for obtaining optically active alcohols is resolution of racemic alcohols catalyzed by enzyme in organic solvents by the esterification reaction.
利用脂肪酶在有机溶剂中催化对映选择性酯化反应对外消旋薄荷醇进行了有效的光学拆分。
Optical resolution of racemic menthol has been efficiently achieved by lipase catalyzed enantioselective esterification in an organic solvent.
对于不对称性合成反应或者动力学拆分的替代反应有动态动力学拆分、消旋化和对映会聚转化等。
The alternatives of asymmetric synthesis or kinetic resolution included: dynamic kinetic resolution, deracemisation and enantioconvergent transformations.
方法以苯乙酸为原料，经磺化、拆分、酰化、酰胺化和取代五步反应合成头孢磺啶。
METHODS Cefsulodin was prepared, taking phenylacetic acid as the starting material, followed by sulfonation, resolution, acylation, amidation and substitution, in 5 steps totally.
苯甲酰氯和d酒石酸反应生成d 2, 3二苯甲酰酒石酸酐，后者于丙酮水溶液中水解得到拆分剂d 2, 3二苯甲酰酒石酸。
The resolving reagent, D-2, 3-dibenzoyl tartaric acid was obtained by hydrolyzation of D-2, 3-dibenzoyl tartaric anhydride prepared by reaction of benzoyl chloride with D-tartaric acid.
通过微水相优化拆分制备S-2-苯基丙酸的反应条件，确定了青霉素酰化酶拆分制备S-2-苯基丙酸的最佳工艺参数。
S-2-phenylpropionic acid was obtained by hydrolysis of 2-phenylpropionic ester catalyzed by penicillin G acylase (PGA) in the micro-aqueous phase.
以1- 苯基- 2-丙胺为原料，经N- 甲基化、拆分、N-炔基化、成盐共4步反应合成盐酸司来吉兰，总收率为42。
From 1-phenyl-2-propylamine, selegiline hydrochloride, an anti-Parksins drug, was synthesized via N-methylation, enantiomer separation, N-alkylation and salt formation with an overall yield of 42.2%.
方法：以5-氰基苯酞为起始原料，经亲核加成、水解、化学拆分、环化和成盐等反应制得抗抑郁药草酸依地普仑。
Methods:Starting from 5-cyanophthalide, escitalopram oxalate was prepared via several steps including nucleophilic addition, hydrolysis, chemical separation, cyclization and salt formation.
而传统的拆分法仅能获得最高50%的产率，还需要繁琐的步骤来分离反应原料和产物。
However, the most maximum theoretical yield of classical kinetic resolution is limited to 50% and the tedious procedures for the separation of the starting material and the product are inevitable.
研究了固定化米曲霉菌光学拆分N-乙酰-D，L-丙氨酸反应过程的速率控制步骤。
The rate-controlling step of resoluting N-acetyl-D, L-alanine with porous immobilized Aspergillus Oryzae cells was studied.
研究了固定化米曲霉菌光学拆分N-乙酰-D，L-丙氨酸反应过程的速率控制步骤。
The rate-controlling step of resoluting N-acetyl-D, L-alanine with porous immobilized Aspergillus Oryzae cells was studied.
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