目的研制针对人补体膜攻击复合物(MAC)新抗原的特异性单克隆抗体。
Objective To prepare monoclonal antibody (McAb) against neoantigen of the human complement membrane attack complex (MAC).
而抗体介导的免疫治疗的关键是靶抗原的特异性强,抗体的免疫原性低及亲和力高等。
The key of antibody-mediated immunological therapy is strong specificity of target antigen, low immunogenicity, high affinity of antibody and so on.
结论NV-HC/NS3能诱导小鼠产生针对靶抗原的特异性免疫应答,发挥预防甚至治疗效应。
Conclusions Specific immune activity could be induced by immunization with NV-HC/NS3. Such effects are immunoprophylactic and immunotherapeutic.
结论:口服抗原可以引起受者对异基因抗原的特异性免疫反应降低,使受者的心脏移植存活期延长。
Conclusion Oral administration of alloantigen can down-regulate the immune response to histocompatibility antigens, prolong the survival times of heart allografts.
目的克隆白癜风患者淋巴细胞中原始配对的自身抗体基因,构建噬菌体抗体库并筛选针对黑素细胞膜抗原的特异性抗体。
AIM: To obtain in situ pairing of the variable region genes of the heavy and light chains of vitiligo patients' lymphocytes, then construct and screen a human ScFv phage antibody library.
结论:用体外免疫法制备乙肝病毒特异性转移因子工艺稳定,制备的转移因子符合质量标准,具有对乙肝病毒抗原的特异性。
Conclusion: the method is simple and stable, whose product of the specific transfer factor of HBV met the quality standard with specific immune activity to HBV-antigen.
克隆与表达弓形虫缓殖子期特异性抗原1(BAG1)的基因,并分析重组抗原的免疫反应性。
Clone and express bradyzoite antigen 1(BAG1) gene of T. gondii, and analyze the immunoreactivity of the recombinant product.
研究了姜片吸虫成虫冷浸抗原检测姜片吸虫病患者血清抗体的敏感性和特异性及其在流行病和临床上的应用价值。
This paper studied sensitivity, specificity and practical value and significance of ELISA in the detection of antibodies against Fasciolopsis buski in human sera.
这显示了巢蛋白和阶段特异性胚胎抗原-1在大鼠2型星形胶质细胞中的表达。
It shows the role of TNF-alpha and its receptors in the production of beta-1,4 galactosyltransferase I and V mRNAs by rat primary astrocytes.
目的研究血清组织多肽特异性抗原(TPS)在乳腺癌患者血清中的表达水平及其对乳腺癌的临床应用价值。
Objective To investigate the expression of serum tissue polypeptide-specific antigen (TPS) in breast cancer patients and its clinical value in such cases.
目的探讨组织多肽特异性抗原(TPS)对原发性肝癌的临床应用价值,并与甲胎蛋白(afp)进行比较。
Objective to evaluate the clinical value of serum tissue polypeptide specific antigen (TPS) for primary hepatic cancer in comparison with alpha-fetoprotein (AFP).
目的探讨血清组织多肽特异性抗原(TPS)在消化系统恶性肿瘤中的临床应用价值。
Objective To assess the clinical role of serum tissue polypeptide specific antigen (TPS) in patients with carcinoma of digestive system.
目的探讨结直肠癌患者血循环中抗-癌胚抗原特异性抗体的存在情况和及其临床意义。
Objective To evaluate the clinical significance of anti-CEA antibodies in the serum of patients with colorectal carcinoma.
将高致敏患者采用PRA单抗原磁珠检测的抗hla特异性抗体的荧光强度转换为MESF单位。
Fluorescence intensity values of anti-HLA specific antibodies determined by Flow PRA single antigen beads of highly sensitized patients were converted into MESF units.
细胞在成熟过程中通过T细胞表面受体基因重排,从而具有特异性识别抗原的能力,在这一过程中的任何失调都会导致疾病。
T cell receptor (TCR)gene rearrangement is an important event in T cell ontogeny that enables T cells to specifically recognise antigens, and any dysregulation in this process may result in diseases.
重组抗原与粗抗原相比,具有相同的敏感性和更高的特异性。
The results showed that the recombinant antigens were more sensitive and specific than the crude antigen.
方法利用抗原、抗体特异性结合原理,在组织和细胞中进行抗原、抗体准确定性、定位的检测。
Methods:Applying the principle of specific binding of antibody and antigen, make detection on accurate localization and qualitaliveness in tissues and cells.
我们知道,人体对外来抗原的免疫应答依赖t细胞和特异性抗原递呈细胞(APC)之间协调的相互作用。
It is generally accepted that normal immune response to extrinsic antigens depends on coordinating interaction between t cells and antigen presenting cells (APCs).
与不同抗原蛋白的ELISA反应呈特异性阳性反应。
It was positively related to different antigen protein ELISA reaction.
结论卵巢癌细胞冻融抗原诱导的CTL在体外具有很强的增殖能力和抗原特异性杀伤卵巢癌细胞的作用。
Conclusion CTL induced by ovarian carcinoma freeze-thaw antigen has high proliferative ability and antigenic specificity against ovarian carcinoma cells in vitro.
目的探讨白念珠菌烯醇化酶的抗原特异性。
Objective To evaluate the antigenic specificity of the enolase.
结论正常人黑素细胞的促淋巴细胞转化增殖的特异性抗原作用较弱。
Conclusion as a specific antigen in mixed melanocyte lymphocyte reaction, melanocyte has a weak effect on the lymphocytes.
目的体外建立可长期培养的抗原特异性T细胞系及克隆,并分析其T细胞受体的使用情况。
Objective To establish long-term cultured antigen-specific T cell line and clones and to analyze their T cell receptor usage.
然而,与抗体的其他作用机制相比,抗体诱发肿瘤抗原特异性免疫应答的能力很少受到关注。
However, the ability of antibodies to initiate tumour-antigen-specific immune responses has received less attention than have other mechanisms of antibody action.
各病毒内部有共同的属特异性抗原,但大多数病毒表面蛋白无血清学交叉反应。
A common genus antigen can be detected in disrupted virions of all species, but most species show no serological cross reactions.
酶免疫分析技术的质量依赖于抗原的纯度、抗体的特异性、合适标记酶的选用,其灵敏度取决于标记酶的高度纯化和高转化率。
The quality of an enzyme immunoassays depends very much on the purity of the antigen or hapten used for conjugation, the specificity of the antibody and the choice of a suitable enzyme label.
目的:分析鸡卵核提取物中检测混合性结缔组织病(MCTD)的特异性抗原成份。
Objective: To analyse the specific antigens extracted from egg nucleus as diagnostic antigens in patients with mixed connective tissue disease (MCTD).
目的建立抗原特异性T淋巴细胞克隆的方法。
Objective To establish the method of alloantigen specific t lymphocyte clones.
目的建立抗原特异性T淋巴细胞克隆的方法。
Objective To establish the method of alloantigen specific t lymphocyte clones.
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