我认为重大问题必须找我商量。
我是在一个不正常的家庭里长大的，所以乱发脾气是我的一大问题。
Because I grew up in a dysfunctional family, anger is a big issue for me.
我认为这也是一个需要我们高度关注的大问题。
I think this is also a big problem which needs our great attention.
这是个大问题，我没有一个对任何人都适用的简单答案。
This is a big question, and I don't have a single answer for everyone.
我感到每一个地方都隐藏着这种神秘。每天，我心里产生的最大问题是：什么时候，啊！
Something undreamt of was lurking everywhere and the uppermost question every day was: when, Oh! When would we come across it?
现在轮到你了，这是一个大问题，我知道……但是你感到幸福吗？
Over to you now. It's a big question, I know... but do you feel happy?
虽然不算什么大问题，我发现打气筒的一个零件掉在自比利时泽布鲁日出发以来的路上。
Hardly a major problem though, unless, that is, it then turns out that part of your bicycle pump has gone missing somewhere along the way from Zeebrugge.
但这对我来说也是一个大问题。
在字节码生成的一般性问题方面，我列出了一个大问题：需要确保正在生成的代码符合JVM规范。
In the category of general problems with bytecode generation, I'd list one big issue: the need to make sure that the code you're generating is going to be valid according to the JVM specification.
这是我生活中的一大问题。
她说上帝还不想抛弃我，不会有什么大问题。
She said that God was not through with me yet; there was no way that this was going to be a major problem.
一位男士曾坦白地说；“一个我无法回答的大问题是：女士想要的是什么？ ”？
Once a man confessed, "The great question I have not been able to answer is What does a woman want?"
这确实是个大问题，也是真正难倒我的问题。
这一点对我来说，其实并不是大问题。
事实上，这一事件已经变成一个大问题，我认为这件事表明一个事实，即种族问题仍然是困扰我们社会的一个方面。
The fact that this has become such a big issue I think is indicative of the fact that race is still a troubling aspect of our society.
在这里是个大问题，我在印尼倒是遇到一个有趣的故事，在印尼所有的学校里在操场上通常有一个卖玩具的人。
But there was one interesting anecdote that I found in Indonesia. In all schools in Indonesia, there is usually a toy seller in the playground.
可事实却不是这样：通常情况下，当遇到我们一生中的重大问题时，比如——我是否应当接受这份工作？
The truth is that quite often, when it comes to the big questions in our lives — Should I take the job?
以往，我也曾在一些重大问题上改变自己的观点。
In the past I've changed my opinions on some important issues.
我不认为文化差异足以造成交往的大问题。
I don't think cultural difference is the essential problem for communication.
我将这些邮件过滤到一个每夜查看的文件夹，但如果我无法在夜间查看，也不是什么大问题。
I filter these into a folder that I try to review nightly - but if I can't get to it nightly, no big deal.
我作为主持人的最大问题是从同伴分享的角色中回到整个团队中。
My biggest problem as a facilitator was transitioning from the share pair back to full group.
我将以两大问题为重点：首先，涉及关塔纳摩监狱和我们的关押政策的问题；其次，涉及安全与透明度的问题。
And I will focus on two broad areas: first, issues relating to guantanamo and our detention policy; second, issues relating to security and transparency.
一直以来我都想要一个自己的孩子，但我知道我的先天条件是个大问题。
I'd always dreamed of having a child but knew my restricted growth might be an issue.
可是遇到重大问题，我可能就会因为没有钱而吃苦了。
But in matters of greater weight, I may suffer from the want of money.
我们有重大问题得解决，我相信我们能够解决这些问题。
We have got big problems to solve, and I am confident that we can solve them.
对于我来说这样没多大问题，因为我一直都在练习举重，跑步和打篮球，并且70%的时间都是在吃健康食品。
For me this is fine because I am lifting weight, running, and playing basketball and eating healthy 70 percent of the week.
我认为我们面临的最大问题是如何使其保持在预算之内。
I think the biggest problem we're facing is how to bring it in under budget.
我认为我们面临的最大问题是如何使其保持在预算之内。
I think the biggest problem we're facing is how to bring it in under budget.
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