尽管目前困难重重，但应看到光明的一面。
In spite of all the difficulties, we should look on the bright side.
其原因很简单：尽管我们目前面临经济困难，但是在过去一代人的期间内，在中国和世界其他地方产生的繁荣是前所未有的。
The reason for this is simple: notwithstanding our current economic difficulties, the prosperity generated here in China and around the world in the past generation has been unprecedented.
尽管目前有了很多关于核力，核子-核子相互作用甚至是强相互作用的理论，但是各种理论或模型都或多或少地存在一些困难。
At present, though there are many theories about nuclear power and nucleon-nucleon interaction, more difficulties exist in both of these theories or models more or less.
尽管我国经济以一个不错的速度持续增长，我们仍不能小看我们目前所面临的困难。
Although our economy keeps growing at a decent rate, we cannot play down the difficulties our country is facing.
尽管目前的抗病毒治疗进展令人鼓舞，但是联合抗病毒治疗的困难也不断出现，仍需要做更多的工作，以便今后能开发出简单、有效与毒性低的药物。
The headway of antiviral treatment are exciting, however the associated difficulties increase. So it needs more work to develop new drug which are simple, effective and low toxic.
尽管目前的抗病毒治疗进展令人鼓舞，但是联合抗病毒治疗的困难也不断出现，仍需要做更多的工作，以便今后能开发出简单、有效与毒性低的药物。
The headway of antiviral treatment are exciting, however the associated difficulties increase. So it needs more work to develop new drug which are simple, effective and low toxic.
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