结论:生姜油对小鼠佐剂性关节炎有抑制作用,其抗炎作用的机制之一可能与抑制炎症局部前列腺素合成有关。
Conclusion: Ginger Oil has an improvement of adjuvant arthritis in mice and one of its possible mechanisms of action is inhibiting the generation of prostaglandin in the area of inflammation.
方法:采用动物实验方法,观察其对大鼠角叉菜胶足肿胀、大鼠肉芽肿、小鼠疼痛反应、大鼠佐剂性关节炎的影响。
Methods: The effects of southernwood compound to feet swelling, granuloma, pain response and adjuvant arthritis were observed in rats.
方法:制造大鼠佐剂性关节炎模型、小鼠迟发性超敏反应(DTH)模型和醋酸扭体疼痛模型,观察复方黑蚂蚁胶囊的药理作用。
Methods: the adjuvant arthritis model of rats (AA rats), delayed hypersensitivity (DTH) model and the pain model induced by acetic acid in mice were used.
结果对小鼠耳廓炎症、大鼠足跖肿胀、佐剂性关节炎、棉球肉芽肿等均有明显抑制作用(P<0.01);
ResultsThe MAEP could lessen the oedema of mouse's ears and toes, decrease swelling of joints, inhibit inflammatory disease and the granuloma hyperplasia(P<0.01).
结果对小鼠耳廓炎症、大鼠足跖肿胀、佐剂性关节炎、棉球肉芽肿等均有明显抑制作用(P<0.01);
ResultsThe MAEP could lessen the oedema of mouse's ears and toes, decrease swelling of joints, inhibit inflammatory disease and the granuloma hyperplasia(P<0.01).
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