目的：建立一种气相色谱法测定原料药头孢唑肟钠中二氯甲烷和四氢呋喃有机溶剂残留量的方法。
Objective: We detected the content of methylene chloride and diethylene oxide in Ceftizoxime Sodium using head-space GC method.
目的：建立一种气相色谱法同时测定原料药头孢唑林钠中有机溶剂丙酮，二氯甲烷、乙醇残留量的方法。
Objective: Using the headspace Gas - chromatography methods to measure the assay of residual solvent (acetone, ethylene chloride and ethanol) in Cefazolin sodium.
以乙酰乙酸叔丁酯为原料，经过肟化、醚化、氯代酯解反应合成了头孢克肟开环侧链酸。
Cefixime open side chain acid was prepared by oximation, etherification, chlorination, ester decomposition using t-butyl acetoacetate as starting material.
以乙酰乙酸叔丁酯为原料，经过肟化、醚化、氯代酯解反应合成了头孢克肟开环侧链酸。
Cefixime open side chain acid was prepared by oximation, etherification, chlorination, ester decomposition using t-butyl acetoacetate as starting material.
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