他因丧妻失子而悲痛不已。
大年夜原来是应该很快乐，很幸福的，可这个家庭却沉浸在失子之痛中，这不是很可悲吗？
Eve was originally should be very happy, very happy, but the family was immersed in the loss of a child, isn't it sad?
结论人乳腺癌er基因的失活与其基因启动子高甲基化关系密切。
Conclusion the inactivation of er gene has a close relationship with the abnormal methylation of er gene promoter.
PTEN肿瘤抑制因子在乳腺癌中虽常呈失表达，但并不是通过基因突变或促进子甲基化而实现的，因此其失表达的机制还不清楚。
Expression of the PTEN tumor suppressor is frequently lost in breast cancer in the absence of mutation or promoter methylation through as yet undetermined mechanisms.
工厂关闭，几百号人一下子就都失了业。
Several hundred men lost their jobs at a stroke when the factory closed.
我的脑袋一下子蒙得老大老大：我以前听其它店铺的人说过这种事情，在自动取款机上取完钱以后再存一存看看真假，万无一失。
My head suddenly Montevideo boss boss: I was listening to other people who shop said such things, automated teller machines, money later admitted End of a real look at the deposit, foolproof.
一下子要把比尔的头发给割失，一下子把比尔当马骑，一下子给比尔吃沙子。
A bill to the hair to cut off, while the bill when riding horses, while eating sand to bill.
目前研究表明ARF基因在肿瘤发生过程中可有起一定的作用，ARF基因功能的失活可能主要通过该基因启动子高度甲基化。
Recent studies showed that ARF gene may play a role in tumorigenesis; the ARF gene promoter hypermethylation may be the principal mechanism in the inactivation of this gene.
目前研究表明ARF基因在肿瘤发生过程中可有起一定的作用，ARF基因功能的失活可能主要通过该基因启动子高度甲基化。
Recent studies showed that ARF gene may play a role in tumorigenesis; the ARF gene promoter hypermethylation may be the principal mechanism in the inactivation of this gene.
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