目的探讨中国汉族人群5-羟色胺转运体基因连锁多态性区域(5-HTTLPR)与抑郁症及临床特征的相关性。
Objective To investigate the association of the polymorphism of serotonin transporter gene linked polymorphic(5-HTTLPR) region with depression and its clinical symptoms in the Han Chinese.
两个都位于染色体上2P35区域的单核苷酸多态性(SNPs)对于在相关的同种疾病总数的酒精依赖上有着最高程度的相关性。
Two single nucleotide polymorphisms (SNPs), both located onthe chromosomal region 2p35, had the highest degree of associationwith alcohol dependence in a relatively homogenous patient population.
猪主要组织相容性复合体又称猪白细胞抗原复合体(SLA),是猪基因组中基因密度最高的区域之一,也是多态性最高的区域。
The swine major histocompatibility complex or swine leukocyte antigen (SLA) is one of the most gene-dense and the most polymorphism regions in the swine genome.
结论:(1)VDR基因多态性与种族、居住区域不同有关。
Conclusion: it is suggested that (1) VDR gene polymorphism is associated with different nation and region.
遗传物质的多态性是基因功能调节的重要方式之一,基因编码区域单个核苷酸碱基的替换就可能改变蛋白质的结构和功能,对细胞或机体的生理功能产生重要影响。
Genetic Polymorphism is a important regulating type for the gene function, it can influence the protein structure and function by only change a single nucleotide in the coding region.
遗传物质的多态性是基因功能调节的重要方式之一,基因编码区域单个核苷酸碱基的替换就可能改变蛋白质的结构和功能,对细胞或机体的生理功能产生重要影响。
Genetic Polymorphism is a important regulating type for the gene function, it can influence the protein structure and function by only change a single nucleotide in the coding region.
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