GHR基因突变可导致空间构象改变，从而影响其功能，使信号不能正常转导，进而影响GH生理效应的发挥。
The mutation of GHR gene can change its conformation and function, so that the signal transduction will be interfered, and the biological effects of GH will be influenced.
这种效应被认为依赖于每个病人根本的基因突变。
This effect was found to be dependent on the underlying gene mutations in each patient.
霍尔博士寻找了安慰剂效应强度和某些基因突变之间的联系，这些突变被称为“单核苷酸多态性”（SNPs），其基因中单个DNA的碱基“字母”序列发生改变。
Dr Hall looked for links between the placebo effect's strength and certain mutations, known as single nucleotide polymorphisms (SNPs), in which a single DNA "letter" in a gene is changed.
霍尔博士寻找了安慰剂效应强度和某些基因突变之间的联系，这些突变被称为“单核苷酸多态性”（SNPs），其基因中单个DNA的碱基“字母”序列发生改变。
Dr Hall looked for links between the placebo effect's strength and certain mutations, known as single nucleotide polymorphisms (SNPs), in which a single DNA "letter" in a gene is changed.
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