获得性基因异常占乳癌的85%至90%。
Acquired genetic abnormalities account for 85% to 90% of breast cancers.
遗传性基因异常：有些人出生时即具有来自父母的异常基因。
Inherited genetic abnormality: Some people are born with an abnormal gene passed on by a parent.
他们发现零尼古丁或可替宁水平也与基因异常不相关。
They found that there was no level of nicotine or cotinine that did not also correlate with genetic abnormalities.
目的：探讨大肠癌p 16基因异常表达的危险因素。
Objective: to explore the risk factors of P16 protein abnormal expression in colorectal cancer (CRC).
可检测出基因异常的最少肿瘤细胞含量是一个重要变量。
The minimum percentage of tumor cells required to detect genetic abnormalities is a major variable.
遗传性基因异常：有些人出生时即具有来自父母的异常基因。
Some people are born with an abnormal gene passed on by a parent.
目的：研究分析肺腺癌细胞系OM的染色体及基因异常变化。
Objective: To investigate the chromosome and gene alterations in adenocarcinoma of lung cell line, om.
结论间期FISH是检测igh基因异常的快速和敏感的手段。
Conclusion Interphase FISH assay is a rapid and sensitive tool for detecting IGH abnormalities.
广泛的低甲基化和区域性高甲基化是基因异常表达的常见机制。
Global hypomethylation and regional hypermethylation are common mechanisms of aberrant expression of gene.
高达7%的人与非小细胞肺癌—通常无吸烟史—有碱基因异常。
Up to 7% of those with NSCLC - typically patients without a history of smoking - have the ALK gene abnormality.
一项12国联合研究表明，自闭症的发病与特定关键基因异常存在关联。
Key genetic abnormalities linked to autism have been identified in research by scientists from 12 countries.
还有身为这些基因异常的人的一级亲属，但仍未进行检查的那些妇女。
And women who are first-degree relatives of someone with one of those gene abnormalities, but have not yet been tested.
某些基因异常甲基化与结肠癌发生密切相关，且常见于结肠癌发病早期。
The aberrant methylation in some genes is strongly associated with colorectal cancer, and this methylation occurs during the early stage of colorectal cancer.
AAH在免疫组化，形态学，流式细胞计数，基因异常方面与腺癌有共同点。
AAH has been shown to have immunohistochemical, morphometric, flow cytometric and genetic abnormalities overlapping with adenocarcinoma.
FHIT基因异常主要发生在肺鳞癌中，且可能是肺癌发生的早期分子事件。
FHIT transcript abnormality preferentially occur in squamous cell carcinomas, and it might be the early molecular phenomenon of lung cancer.
目的研究脆性组氨酸三聚体（FHIT） 基因异常转录与结肠癌的相关性。
Objective To study the relationship between aberrant FHIT transcription and colon carcinoma.
结论P16基因异常有促进胃癌转移的效应，可作为胃癌预后的一个参考指标。
Conclusion the abnormality of P16 gene may promote the metastasis of gastric carcinoma, and it may also ACTS as the reference mark of prognosis of gastric carcinoma.
检测结果显示汉族孤独症谱系障碍儿童FMR-1基因异常突变率为0.43%。
The incidence of the mutation of FMR-1 gene in the Chinese Han ASD children is 0.43%.
然后这些基因异常会导致出生缺陷或新生儿的健康问题，或者影响胚胎的正常发育。
In turn, those genetic abnormalities may give rise to birth defects or health problems in a child, or make it impossible for an embryo to develop normally.
结论MMD为一种局部因素所致疾病，烟雾病发生与患者的免疫相关基因异常有关。
Conclusion MMD may be induced by local nosogenesis but not systemic immunologic abnormality, and related with the abnormal expression of immune genes.
遗传性耳聋由遗传缺陷引起，与基因异常及相关的综合症关系密切，属临床常见疾病。
Hereditary hearing impairment is caused by genetic defects and is a common clinical disease.
胃癌的发生与多基因异常表达密切相关，其中抑癌基因甲基化是胃癌发生、展的重要机制之一。
The genesis of gastric cancer resulted from abnormal expression of many genes, and methylation of the tumor suppressor genes is one of the major mechanisms of gastric carcinogenesis.
该病是一种遗传性的视网膜退化疾病，由于一个称为RPE65的基因异常，导致视觉进行性退化。
This disease causes progressive deterioration in vision, due to an abnormality in a particular gene called RPE65.
其中涉及多种基因异常，包括易感基因、癌基因、抑癌基因等，对于乳腺癌的诊断、治疗及预后判断均具有提示作用。
Quite a few kinds of genes such as susceptibility gene, oncogene and tumor suppressor genes have been found with implications for diagnosis, therapy and prognosis.
结果：统计比较抗癌药在P53基因正常组和P 53基因异常组中的抑制率，发现多数抗癌药抑制率前者显著地大于后者。
RESULTS: the inhibition rates of majority antitumor drugs in the P53 gene normal group were significantly higher than in the P53 gene abnormal group.
尽管研究人员已经对房室间隔发育的基因控制有了很多认识，但目前还没有确定是哪种基因异常引起房室间隔相关的先天性心脏缺损。
Despite extensive knowledge of the genetic control of AVS development, few genetic lesions have been identified that are responsible for AVS-associated congenital heart defects.
我们想我们可能对导致这种癌症的一组异常基因有了近乎完全的了解。
We think that we may have an almost complete understanding of the set of abnormal genes that drive this cancer.
他们具有来自父母一方的一个异常基因和来自父母另一方的一个正常基因。
They have one abnormal gene from that parent and one normal gene from the other parent.
大多数明显的创始人突变都是隐性的，可以解释这种明显的异常现象：只有双亲都拥有受影响基因副本的人才会生病。
This apparent anomaly is partially explained by the fact that most founder mutations are recessive: only a person with copies of the affected gene from both parents becomes ill.
大多数明显的创始人突变都是隐性的，可以解释这种明显的异常现象：只有双亲都拥有受影响基因副本的人才会生病。
This apparent anomaly is partially explained by the fact that most founder mutations are recessive: only a person with copies of the affected gene from both parents becomes ill.
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