• 滴丸制剂一种固体分散体

    Dripping pill is a dosage form of solid dispersion.

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  • 不同固体分散方法药物的出度影响不大

    Preparation methods had little effect on the dissolution rates of daidzein solid dispersion.

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  • 他克莫司固体分散中可能以无定型态分子状态存在

    Tacrolimus existed as amorphous or molecular state in tacrolimus solid dispersions.

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  • 结论依托度酸固体分散显著提高依托度酸的速率

    Conclusion Etodolac solid dispersion can significantly increase the dissolution rate.

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  • 目的制备地平固体分散体增加其溶解度溶出速度

    OBJECTIVE To improve the solubility and dissolution of nitrendipine by preparing its solid dispersions.

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  • 目的制备卡维地洛固体分散体提高溶解度速率

    OBJECTIVE: To improve the dissolubility and dissolution rate of carvedilol.

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  • 结果固体分散加快药物溶出速率,最佳比例为1∶7。

    Results: The in vitro dissolution rates of ISDN solid dispersion were faster than ISDN.

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  • 最终筛选出合适的处方,制备出了较为理想固体分散体

    We ultimately selected the suitable diclazuril solid dispersions prescription and technology, and prepared ideal diclazuril solid dispersions.

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  • 制得的地沙坦固体分散体稳定具有实际应用价值

    Candesartan SD is a stabilizing system which having actual applied value.

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  • 差分析粉末X衍射结果表明固体分散体槲皮素呈非结晶形式

    The results of DSC and PXRD showed that the quercetin in solid dispersion was amorphous form.

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  • PEG葛根黄酮固体分散体中,分子中的·OH形成更多氢键

    The PEG RP isoflavones solid dispersions formed more hydro-keys resulted by -oh in the molecules.

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  • 结果各种固体分散均能大大增加他克莫司溶解度,加快其溶出

    RESULTS The solubility and in vitro dissolution of all tacrolimus solid dispersions were increased significantly.

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  • 目的 将难性药物阿德福韦制备固体分散增加溶出度。

    Objective To prepare adefovir dipivoxil solid dispersion from poorly-soluble adefovir dipivoxil so as to improve its dissolution rate in vitro.

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  • 结论:伊曲康固体分散明显提高伊曲康唑溶解度速率

    CONCLUSION Itraconazole solid dispersion can significantly increase it's solubility and dissolution rate.

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  • 目的利用固体分散技术制备阿西美辛固体分散体,增加其溶解度溶出速度。

    OBJECTIVE To improve in vitro release of acemetacin, the technology of solid dispersion was used and acemetacin was prepared as solid dispersion.

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  • 目的利用固体分散技术制备固体分散体增加替硝唑溶解度溶出速度

    OBJECTIVE: to prepare tinidazole solid dispersion using the technology of solid dispersion, and to increase the dissolubility and the dissolution rate of tinidazole.

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  • 方法聚乙二醇6000,溶剂-熔融法制备sud - 35固体分散

    METHODS Solid dispersions of SUD-35 were prepared by solvent-fusion method with PEG6000 as carrier.

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  • 药物固体分散体中的溶出度原药粉末显著提高,且随着PVP比例增加而增大。

    The dissolution rate of CyA was increased dramatically after the formation of solid dispersion compared with the pure drug powder. CONCLUSION PVP can enhance the dissolution rate of CyA dramatically.

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  • 结果固体分散体微丸温度湿度稳定对光不稳定,模拟上市包装稳定性良好。

    Results The pellets were stable when exposed to high temperature and high humidity, but sensitive to light.

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  • 制剂制备采用了超临界提取的工艺及环糊精包埋固体分散制剂技术

    It is prepared by supercritical extraction, flocculating and alcohol settling cyclodextrin investing and solid dispersion preparation technique.

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  • 目的优化葛根素磷脂复合物制备工艺研究固体分散体提高葛根素的溶出速率

    OBJECTIVE to optimize preparation techniques for puerarin phytosomes and explore their solid dispersions to increase the dissolution of puerarin in vitro.

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  • 方法:采用溶剂法制固体分散进行溶解度溶出速率测定导数热重分析(DTG)。

    Methods: the solid dispersion was prepared by solvent method. The solubility, the dissolution rate and the derivative thermogravimetry (DTG) were determined.

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  • 方法:将冰片用水溶性辅料聚乙二醇6000制成固体分散体装入胶囊,进行毒理试验

    Method: Bomeolum Syntheticum and PEG 6000 mixing preparative solid dispersion and packed capsules, toxicity was tested.

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  • 结论PVP固体分散可有效提高姜黄素溶解性,同时应用在治疗胃溃疡具有很好的开发前景。

    CONCLUSION The solid dispersion in PVP k30 improves the solubility of curcumin. These findings show a potential application of curcumin SDs as an anti-ulcerogenic drug.

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  • 结论拉曼光谱法快速直接、对样品无损伤,一种新的理想检查固体分散体分散方法

    Conclusion: Raman spectrometry which is fast, direct and non-destructive is an ideal method in examining the dispersivity of solid dispersion.

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  • 结论拉曼光谱法快速直接、对样品无损伤,一种新的理想检查固体分散体分散方法

    Conclusion: Raman spectrometry which is fast, direct and non-destructive is an ideal method for examining the dispersivity of solid dispersion.

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  • 结论拉曼光谱法快速直接、对样品无损伤,一种新的理想检查固体分散体分散方法

    Conclusion: Raman spectrometry which is fast, direct and non-destructive is an ideal method for examining the dispersivity of solid dispersion.

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