目的对与喉鳞状细胞癌关联的基因表达变化的轮廓特征进行描述。
Objective To study characterizing the gene expression profile alterations associated with laryngeal squamous cell carcinoma.
方法应用差异PCR方法检测40例喉鳞状细胞癌及癌旁正常对照组织STK15基因扩增的情况；
Methods STK15 gene amplification in 40 cases carcinoma tissues and normal tissues as control was detected by differential PCR approach.
EGFR表达与喉鳞状细胞癌的病理组织分级及患者5年生存期相关（P< 0 .0 5 ） ；
EGFR expression in LSCC was related to the degree of cell differentiation and 5 years survival rate of patients ( P< 0.05).
目的：研究癌基因stk15在喉鳞状细胞癌中的表达，探讨STK15与喉鳞状细胞癌的相关性。
Objective: to investigate the expression of oncogene STK15 in laryngeal squamous cell carcinoma (LSCC), and therefore to find out the correlation of STK15 and laryngeal squamous cell carcinoma.
目的：本文研究癌基因stk15在喉鳞状细胞癌中的表达情况，探讨STK15与喉鳞状细胞癌的相关性。
Objective: to investigate the expression of oncogene STK15 in laryngeal squamous cell carcinoma, to find out the correlation of STK15 and laryngeal squamous cell carcinoma.
采用比色法对61例喉鳞状细胞癌、25例喉及颈部良性病变患者和40例正常人的血清唾液酸（SA）含量进行测定。
Serum sialic acid (SA) was determined bv colorimetric method in 61 patients with squamous cell carcinoma of the larynx, 25 patients with benign lesion and 40 normal controls.
方法：应用免疫组化方法检测72例喉鳞状细胞癌组织标本中MMP-2和MMP-9蛋白的表达，并与临床病理特征和预后进行对比。
Methods: Immunohistochemistry was used to examine the expression of MMP-2 and MMP-9 in tissue samples of 72 LSCCs and the results were compared to clinical pathological features and prognosis.
方法：应用免疫组化方法检测72例喉鳞状细胞癌组织标本中MMP-2和MMP-9蛋白的表达，并与临床病理特征和预后进行对比。
Methods: Immunohistochemistry was used to examine the expression of MMP-2 and MMP-9 in tissue samples of 72 LSCCs and the results were compared to clinical pathological features and prognosis.
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