目的谷氨酸NMDA受体拮抗剂地卓西平(MK801)对大鼠急性吗啡依赖戒断性情绪反应的影响。
ObjectiveTo investigate the effect of NMDA receptor antagonist MK801 on the negative affection induced by withdrawal from acute morphine dependence in rats.
目的:观察5-羟色胺(5-HT3)受体拮抗药阿扎司琼静脉预先注射对鞘内吗啡所致的瘙痒发生防治效果。
Objective: To evaluate the effects of prophylactic intravenous administration of the 5-hydroxytryptamine subtype 3(5-HT3) receptors antagonist azasetron on intrathecal morphine-induced pruritus.
一氧化氮(NO)是与N甲基D 天(门)冬氨酸(NM DA)受体活性相关的一种细胞内信使分子,在吗啡耐受和依赖中起作用。
Nitric oxide, an intracellular messenger molecule linked to activation of N Methyl D aspartate(NMDA) receptor, plays a role in morphine tolerance and dependence.
目的:探讨5-HT3型受体特异性拮抗剂奥丹西隆对吗啡诱导的条件性位置偏爱(CPP)效应的影响及其可能机制。
OBJECTIVE:To elucidate the effect of ondansetron(OND), a 5-HT3 receptor antagonist, on the morphine-induced conditioned place preference(CPP) in mice and its possible mechanism.
我们发现随着异源二聚体的具体,大脑选择性的对吗啡治疗慢性疼痛起作用,阻碍单个受体对吗啡止痛作用的传导。
"We found that the brain selectively responds to chronic morphine by increasing heteromer abundance, blocking individual receptors from signaling the analgesic response to morphine, " said Dr. Devi.
我们发现随着异源二聚体的具体,大脑选择性的对吗啡治疗慢性疼痛起作用,阻碍单个受体对吗啡止痛作用的传导。
"We found that the brain selectively responds to chronic morphine by increasing heteromer abundance, blocking individual receptors from signaling the analgesic response to morphine, " said Dr. Devi.
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