• 目的谷氨酸NMDA受体拮抗剂卓西平(MK801)对大鼠急性吗啡依赖戒断性情绪反应影响

    ObjectiveTo investigate the effect of NMDA receptor antagonist MK801 on the negative affection induced by withdrawal from acute morphine dependence in rats.

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  • 目的观察5-羟色胺(5-HT3受体抗药阿扎司琼静脉预先注射对吗啡所致的瘙痒发生防治效果

    Objective: To evaluate the effects of prophylactic intravenous administration of the 5-hydroxytryptamine subtype 3(5-HT3) receptors antagonist azasetron on intrathecal morphine-induced pruritus.

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  • 一氧化氮(NO)是与N甲基D 天(门)冬氨酸NM DA受体活性相关一种细胞内信使分子吗啡耐受依赖作用

    Nitric oxide, an intracellular messenger molecule linked to activation of N Methyl D aspartate(NMDA) receptor, plays a role in morphine tolerance and dependence.

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  • 目的探讨5-HT3型受体特异性拮抗剂奥丹西隆吗啡诱导的条件性位置偏爱CPP效应影响及其可能机制

    OBJECTIVE:To elucidate the effect of ondansetron(OND), a 5-HT3 receptor antagonist, on the morphine-induced conditioned place preference(CPP) in mice and its possible mechanism.

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  • 我们发现随着异源二聚体的具体,大脑选择性吗啡治疗慢性疼痛起作用,阻碍单个受体吗啡止痛作用传导

    "We found that the brain selectively responds to chronic morphine by increasing heteromer abundance, blocking individual receptors from signaling the analgesic response to morphine, " said Dr. Devi.

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  • 我们发现随着异源二聚体的具体,大脑选择性吗啡治疗慢性疼痛起作用,阻碍单个受体吗啡止痛作用传导

    "We found that the brain selectively responds to chronic morphine by increasing heteromer abundance, blocking individual receptors from signaling the analgesic response to morphine, " said Dr. Devi.

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